NHE wrote:
I have read much on DMSA challenge tests over the past few days and currently have more questions than answers. Some published journal articles indicate that they are not useful in diagnosing past metal exposure (
1,
2).
It appears that the papers are referring to the validity (or lack thereof) of a DMSA challenge test to assess mercury exposure. As stated in the first reference,
Quote:
Another metal that might be assessed in this way is mercury. DMSA mobilizes mercury effectively in both animals (20-25) and in humans (8,17,26-31). However, unlike lead, mercury undergoes relatively little bioaccumulation. It is excreted with a half-life of 1-2 months (17,32-35).
I am still trying to assess what the DMSA challenge test results might mean in relation to lead.
In addition, at least
one paper states that some nanozeolites can damage the cell membrane and induce necrotic cell death
in vitro.
There are still more questions than answers...

NHE