omg, i feel like i'm playing whack a mole with this glutathione issue!! lol!!
your body is supposed to make it.
wikipedia "Glutathione is not an essential nutrient (meaning it does not have to be obtained via food), since it can be synthesized in the body from the amino acids L-cysteine, L-glutamic acid, and glycine... Cysteine is the rate-limiting factor in cellular glutathione synthesis
, since this amino acid is relatively rare in foodstuffs."
healthy food sources of cysteine:http://whfoods.org/genpage.php?tname=nutrient&dbid=54
"Cysteine is found in a variety of foods including poultry, yogurt, egg yolks, red peppers, garlic, onions, broccoli, Brussel sprouts, oats, and wheat germ."
wikipedia "Glutathione is synthesized in two adenosine triphosphate-dependent steps
oh hello there, ATP - so that looks like a magnesium connection to glutathione status too...
wikipedia: "First, gamma-glutamylcysteine is synthesized from L-glutamate and cysteine via the enzyme gamma-glutamylcysteine synthetase"
"Gamma-glutamylcysteine synthetase (EC 188.8.131.52) (glutamate cysteine ligase, GCL) is the first enzyme in the glutathione biosynthesis pathway"
Glutamate—cysteine ligase catalytic subunit (GCLC) http://en.wikipedia.org/wiki/GCLC
okay, gamma-glutamylcysteine synthetase aka GCLC. "NO-induced expression of GCLC is fully dependent on the presence of zinc
getting too late for me to sit here and tease out the selenium connection. tired and hungry!
i wish i could have a quick-reference list of all the zinc-dependent enzymes.
links up to several older discussions on glutathione over recent yearsgeneral-discussion-f1/topic19670-60.html#p191336
my approach: no meds so far - just nutrient-dense anti-inflammatory whole foods, and supplements where needed
info: www.whfoods.com, www.nutritiondata.com