2006 study: Vitamin D insufficiency...role of mag deficiency

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2006 study: Vitamin D insufficiency...role of mag deficiency

Postby jimmylegs » Sun Nov 25, 2018 6:51 am

i should have filed this here years ago. it's been kicking around the forum since 2013:

Vitamin D insufficiency and the blunted PTH response in established osteoporosis: the role of magnesium deficiency (2006)

"intro: Vitamin D insufficiency is common, however within individuals, not all manifest the biochemical effects of PTH excess. This further extends to patients with established osteoporosis. The mechanism underlying the blunted PTH response is unclear but may be related to magnesium (Mg) deficiency.

methods: 30 patients (10 women in 3 groups) were evaluated prospectively measuring calcium, PTH, Mg retention (Mg loading test), dietary nutrient intake (calcium, vitamin D, Mg) and bone turnover markers (serum CTX & P1CP).

results: All subjects, within the low vitamin D and low PTH group following the magnesium loading test had evidence of Mg depletion ... Following oral supplementation bone turnover increased

conclusions: This study confirms that in patients with established osteoporosis, there is also a distinct group with a low vitamin D and a blunted PTH level and that Mg deficiency (as measured by the Mg loading test) is an important contributing factor."
take control of your own health
pursue optimal self care at least as actively as a diagnosis
ask for referrals to preventive health care specialists eg dietitians
don't let suboptimal self care muddy any underlying diagnostic picture!
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Re: 2006 study: Vitamin D insufficiency...role of mag defici

Postby NHE » Sun Nov 25, 2018 8:20 am

Here's a link to the full abstract.

Vitamin D insufficiency and the blunted PTH response in established osteoporosis: the role of magnesium deficiency. Osteoporos Int. 2006;17(7):1013-21.

https://www.ncbi.nlm.nih.gov/pubmed/16596461
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