They say things like "it doesn't suit me" or "it makes me drowsy next day" or "I still couldn't sleep" or other such vague things. I don't know any more than that, except I have never heard of it actually inducing a relapse, nor did I see that they almost knew it would in that abstract. If they gave her 10 mg she will almost certainly have still felt drowsy next day, even if it wasn't timed release. You say you have also taken 10 mg and think you feel worse next day: try cutting it down to 3 mg.
An Itinerary in Light and Shadow Completed Dr Charles Stratton / Dr David Wheldon abx regime for aggressive secondary progressive MS in June 2007, after four years. Still improving with no relapses since starting. Can't run but can paint all day.