Thanks Dignan, I agree it is difiult to extrapolate the findings. However this section caught my attention:
We also showed that when LA and ALC were combined at 0.1 μM each or at 1μM each, they displayed significant preventative effects. However, when they were combined at 10 μM each, no protective effects were observed, and when combined at 10 and 100 μM or at 100 μM each, negative effects occurred (data not shown), though the best doses for LA and ALC alone are 10 and 100 μM, respectively. These data suggested
that simply combining multiple agents at each one’s optimal dosage might be ineffective or counterproductive, again illustrating the necessity of determining optimal doses of the combined agents.
Although the stated doses are irrelevant; high doses may have a negative impact. Another case of the 'Goldilocks trap'.