Red Wine

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Red Wine

Postby L » Sat Sep 20, 2008 5:55 am

Everyone must be feeling a bit down after the Tovaxin results. Look on the bright side - they fared better than current medications.

Anyway, we all love the idea of DIY self medication. There has been that Tryptophan and then there was something else before it and later N Acetyl Glucosamine (which I take religiously although it didn't prevent my last relapse) and nicotinamide (protects the axons - take it when you have an attack) Anyway, now there's red wine.

We all know that red wine is a powerful antioxidant, but maybne it does more than that? Well, the researchers don't seem to have a clue but, I muist say, when I was drinking far too much red wine a couple of years ago I did feel lots better and I was convinced that it was doing my ms good.

Anyway, I've ordered a big bottle of Resveritrol. I don't think it's going to do much for my MS, I'm in a right state, but, as my Grandmother would say, "you never know".




' Red wine molecule might battle Multiple Sclerosis 19 September 2008


Resveratrol, the compound in red wine that previous research has linked to longevity, has shown promise in an animal model of multiple sclerosis.

Mice with the MS-like condition called Wallerian degeneration slow (WldS) showed an initial weight gain when given resveratrol, researchers at the University of Utah reported Thursday at the World Congress on Treatment and Research in Multiple Sclerosis, in Montreal.

The weight gain occurred in the first two weeks of treatment. A microscopic study of nerve cell tissue at five weeks did not show any positive effect.

"They didn't look at the tissue under the microscope in the first two weeks," said Dr. John Richert, executive vice president for the research and clinical program of the Multiple Sclerosis Society. "Obviously, lots of things can make animals gain weight."

But weight gain of any kind is an encouraging sign in MS treatment, Richert said. "In inflammatory animal models of MS, one of the tell-tale clinical signs of the disease is weight loss. Weight loss often goes hand in hand with loss of neurological function."

The study "poses some questions," Richert said. "Obviously, a lot more needs to be done to see if the weight gain shows a beneficial effect on the disease process. This is evidence that it should be studied further." '


Source: News & World Report © 2008 U.S. News & World Report (19/09/08)
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Postby gwa » Sat Sep 20, 2008 6:56 am

The problem with drinking red wine to get the Resveratrol is that you would need about 400 glasses or bottles a day, can't remember which, to get the effects shown in the mice.

Unless you are French, that is probably going to do you in.

gwa :) :)
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Postby L » Sat Sep 20, 2008 9:27 am

gwa wrote:The problem with drinking red wine to get the Resveratrol is that you would need about 400 glasses or bottles a day, can't remember which, to get the effects shown in the mice.

Unless you are French, that is probably going to do you in.

gwa :) :)


In my heyday I was getting there - but the capsules that I got claim to have the equivalent amount of Resveratrol in them as found in sixty glasses of wine. Four of those a day and I shall be skipping around again in no time ☺
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Postby gwa » Sat Sep 20, 2008 10:05 am

L wrote:
gwa wrote:The problem with drinking red wine to get the Resveratrol is that you would need about 400 glasses or bottles a day, can't remember which, to get the effects shown in the mice.

Unless you are French, that is probably going to do you in.

gwa :) :)


Four of those a day and I shall be skipping around again in no time ☺


Post pictures or a video when this day happens. Wishing you luck with your own trial.

gwa
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Postby CureOrBust » Sat Sep 20, 2008 4:27 pm

I went for a quick check to see what dosage my supplier had, and one of the products had the following warning:
Cell culture studies suggest that resveratrol is a weak inhibitor of the liver metabolism system P450 3A4, but this interaction is of unknown significance in humans. Ingestion of large amounts of resveratrol may increase blood levels of drugs known to be metabolized via CYP3A4. This would include statins, calcium channel blockers, certain immunosuppressant drugs (e.g. cyclosporine), and drugs for erectile dysfunction (e.g. sildenafil). Caution is advised if used concurrently with anticoagulants or antiplatelet drugs such as Clopidogrel (Plavix).
http://www.iherb.com/ProductDetails.aspx?c=1&pid=-4045429288781190332&at=0
At least one of those medications (statins, "immunosuppressant") are in use by some MS sufferers.
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