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Dalfampridine, or Ampyra, is a potassium channel blocker that is shown to improve visual function, motor skills and relieve fatigue in MS patients.

Need Ampyra Advice

I am torn. My left leg is weaker than my right and always have been. I have been working out faithfully and it remains the same. Although both legs are getting stronger, the left will never catch up to the right. This weakness causes a discernible limp and left legs tires more quickly. Last year my neuro gave me a prescription for Ampyra and it was my choice as to whether I wanted to start ...
Read more : Need Ampyra Advice | Views : 984 | Replies : 3

Too expensive

Well I was about to receive a 30 day supply of Ampyra. But when the pharmacy informed me of the cost, I cancelled it. I have a high deductible in my Rx insurance so the 30 day supply would cost me over $1400! :-x
And the second month would be almost as much.
I could afford to pay it but I simply refuse to do it. That ...
Read more : Too expensive | Views : 1329 | Replies : 8

Fampyra and 4-AP

I tried Fampyra for two weeks with no clear reaktion in walking improvement. (MS since 23 years, EDSS 6,5)
I made a break for 3 days (no significant difference, perhaps right leg worse)
Two years ago I made a test with 4-AP, 4x5mg/day.

Now I start again with a 4 week test on Fampyra.
Does anyone have experiance with a combination of Fampyra and 4-AP?

Read more : Fampyra and 4-AP | Views : 1593 | Replies : 1

Vision Improvements with Ampyra?

Is there anyone here with optic neuritis who has noticed any vision improvements after taking Ampyra? I was dx with MS about 5 years ago after going in for vision problems (which ended up being optic neuritis.) My vision has never fully recovered. I think my good eye is at about 20/30 or 40 and the bad one is close to 20/200. Unfortunately my damaged/blind spot is in my central vision in the affected eye. ...
Read more : Vision Improvements with Ampyra? | Views : 1324 | Replies : 2

Natural alternative/substitute to ampyra

Hi all
I was just wondering is there any natural/homeopathic alternative to ampyra showing reasonable results. Any supplements etc. that have a positive result with stiffness and spasticity? Any recommendations would be gratefully appreciated.

Read more : Natural alternative/substitute to ampyra | Views : 2396 | Replies : 4

Ampyra® two-year safety data presented at ECTRIMS


Acorda Therapeutics, Inc. today announced safety data from more than 62,400 people with multiple sclerosis (MS) taking Ampyra (dalfampridine) Extended Release Tablets, 10 mg during the first two years of availability in the United States. The data showed that the safety profile of Ampyra is similar to that observed in clinical trials.

This analysis was presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), being held ...
Read more : Ampyra® two-year safety data presented at ECTRIMS | Views : 1360 | Replies : 0

Would like to hear from people using Ampyra

Reply to topic in 'general' section:

I have been using it for about 2 months. It's definitely not a wonder drug. I'm really not sure if I am walking any better - maybe marginally. As that research from squiffy stated, I think I would get more or equal benefit from physio.
I think I might go off it for awhile and compare.
When you have a progressive condition like MS, you get in the habit ...
Read more : Would like to hear from people using Ampyra | Views : 3590 | Replies : 18

No added benefit proven for Fampiridine in MS


Drug manufacturer did not present evaluable study data on the appropriate comparator therapy

Fampridine (trade name Fampyra®) has been approved in Germany since July 2011 for adult patients suffering from a higher grade walking disability (grades 4 to 7 on the EDSS disability status scale), as a result of multiple sclerosis (MS). The German Institute for Quality and Efficiency in Health Care (IQWiG) has assessed the added benefit of the drug pursuant to the ...
Read more : No added benefit proven for Fampiridine in MS | Views : 2408 | Replies : 5

Acorda's Ampyra fails main goal of post-marketing study

Acorda's Ampyra fails main goal of post-marketing study

Mon Aug 13, 2012 7:39am EDT
(Reuters) - Acorda Therapeutics Inc said a post-marketing study of its multiple sclerosis drug Ampyra failed to meet the main trial goal of an improvement in patients' walking speed.

The 5 mg and 10 mg doses of Ampyra did not yield statistically significant results on the timed 25-foot walk test as compared with the placebo group, the company said.

Read more : Acorda's Ampyra fails main goal of post-marketing study | Views : 1491 | Replies : 3


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