I have been a subject in the Phase 11 study of the safety and efficacy of Teriflunomide for approximately 7 1/2 years with positive results.

Anyone else out there on this drug with similar results

I have been following the news on CCSV1 and like many I'm sure would be willing to travel for this procedure when it becomes available

* Teriflunomide reduces cerebral lesions in Phase II trial * Sanofi drug given as add-on therapy to interferon beta




LONDON, Sept 11 (Reuters) - Patients given an experimental multiple sclerosis tablet from Sanofi-Aventis (SASY.PA) showed a significant improvement compared to those on placebo in a mid-stage test, researchers said on Friday.

Teriflunomide, which was used as an add-on therapy to interferon beta in the Phase II clinical trial, is one of a number of MS ...

I was recently diagnosed with MS-lesions on MRI--one CIS-which affected my left eye over several weeks--I have been offered the opportunity to participate in the teraflunomide study--can someone tell me what exactly do they test you for prior to being accepted and during? I understand that they will be checking for changes in RBC, WBC, liver enzymes etc. but what else are they checking?

I am new here. I just want to share about the medicine.. teriflunomide.. doctor said it was placebo which every pill could be consist of 7gram or 14 gram of it..

but then the side effect is quite critical.. seems the pill is suppressed the antibody.. and i have hairloss...i kind of scared. my leucosyt is dropped from 4,0 to 2,4.. while that happened..i kinda felt dizzy and no appetite, no encouragement to do things...easy ...

http://www.nationalmssociety.org/research-2006may12.asp


I am getting a deja-vu feeling with these trials. None ever seem to finish and hit the market! (or is it just me).

Ian

An update on a phase II study of teriflunomide...



A Phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses.

Neurology. 2006 Mar 28;66(6):894-900.
O'Connor PW, Li D, Freedman MS, Bar-Or A, Rice GP, Confavreux C, Paty DW, Stewart JA, Scheyer R; Teriflunomide Multiple Sclerosis Trial Group; University of British Columbia MS/MRI Research Group.
University of Toronto, Ontario, Canada. oconnorp@smh.toronto.on.ca

BACKGROUND: Teriflunomide, a dihydro-orotate dehydrogenase ...

I've been wondering when there would be more information about the teriflunomide trials in North America. I guess it takes a lot of work to get a phase III study up and running.



Phase III Study of Teriflunomide in Reducing the Frequency of Relapses and Accumulation of Disability in Patients with Multiple Sclerosis

This study is not yet open for patient recruitment.

Sponsored by: Aventis Pharmaceuticals

Purpose
Multinational Study; 2 years treatment duration; objectives are ...

Has anyone enrolled in a Teriflunomide study? I have been reading about a phase III study starting soon, but have not found a location. Any info would help.

Thanks
T

Does anyone have any information regarding this drug? It is going into Phase III trials and is an oral treatment for RR MS.