I was one of the first patients to try Avonex after a single episode. I took part in the CHAMPS trial roughly nine years ago and I was on Avonex until July of this year.
There were definite benefits to taking the shot once a week. I mastered doing it right in my thigh, alternating thighs from one week to the other. I hated the side effects. I still remember feeling like crap for two ...