This Is MS Multiple Sclerosis Community: Knowledge & Support

Mid-term sustained relief from headaches after balloon angioplasty of the internal jugular veins in patients with multiple sclerosis.

https://www.ncbi.nlm.nih.gov/pubmed/29360844

Abstract
OBJECTIVES:

Multiple sclerosis (MS) patients frequently suffer from headaches and fatigue, and many reports have linked headaches with intracranial and/or extracranial venous obstruction. We therefore designed a study involving MS patients diagnosed with obstructive disease of internal jugular veins (IJVs), with the aim of evaluating the impact of percutaneous ...

Cerebrospinal Fluid Dynamics in Patients with Multiple Sclerosis: The Role of Phase-Contrast MRI in the Differential Diagnosis of Active and Chronic Disease

https://synapse.koreamed.org/DOIx.php?i ... 18.19.1.72

Conclusion

This study indicated that CSF flow is affected in MS patients, contrary to the hypothesis that CCSVI-induced CSF flow decreases in MS patients. These findings may be explained by atrophy-dependent ventricular dilatation, which may occur at every stage of MS.

Jugular Anomalies in Multiple Sclerosis Are Associated with Increased Collateral Venous Flow

http://www.ajnr.org/content/early/2017/05/25/ajnr.A5219

CONCLUSIONS: Compared with healthy controls, patients with MS exhibit reduced venous flow in the main extracerebral drainage vein (internal jugular vein). In contrast, flow in the paraspinal venous collaterals is elevated in patients with MS and exacerbated by venous stenosis. Collateral drainage may be a compensatory response to internal jugular vein flow reduction.

From CCSVI / CCSVO specialist Dr Paul Thibault :

The concern I have is that people (medical doctors, patients, and the general public) will become disillusioned by the many studies (including Zamboni et al), which refute the use of venoplasty to achieve a "cure" for MSi. Zamboni has highlighted the connection between MS and a chronic venous disease, which I appreciate. However, since 2011 I have suspected his theory that venous obstructions cause demyelinationi (due ...

no ifs, no buts.

CCSVI is dead and buried. It was fakery and bad science and promoted by Cheerleader.

MSers wasted time and money.

If it really worked (now around for 10 years) this site would have shut down as readers would have all experienced the claimed miracles.

Next time you aggressively promote a treatment - check the facts Cheerleader.


http://multiple-sclerosis-research.blog ... peace.html

http://www.thisisms.com/forum/general-discussion-f1/topic29604.html#p250840

Percutaneous angioplasty of internal jugular and azygous veins in patients with chronic cerebrospinal venous insufficiency and multiple sclerosis: preliminary results for a randomized controlled trial

Source: https://etd.adm.unipi.it/t/etd-06192017-102412/

Conclusion:

Study’s aim is to assess the efficacy of PTA on CCSVI and MS patients’ functional disability. Endovascular treatment of the IJV is proven to be a safe procedure (major complication <0,05%) with no significant improvement of IJV flow haemodynamic parameters and ...

More information on the damage to astronaut eyes during long term spaceflight. It was on CNN's website so probably fake news. Just kidding. Thought this was interesting, the idea that eyes act like a pressure release valve to a brain that has too much cerebrospinal fluid pressure.

http://www.cnn.com/2017/11/01/health/br ... index.html

Given the connection between the eye, the optic nerve and the brain, combined with the fluid shift astronauts experience, ...

Could it be that CCSVI just makes MS worse?

This is an idea that came to me after reading an article named "The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766379/). I enclose here some quotes:

"Their location (of the lesions), shape and patterns of active demyelination are compatible with the view that they are driven by a soluble factor, produced in the inflammatory infiltrates of ...

The impact of vascular risk factors on brain volume and lesion load in patients with early multiple sclerosis

http://journals.sagepub.com/doi/abs/10. ... 8517736149

Conclusion:

VRF are associated with lower brain volume already in early MS but do not lead to increased brain volume loss during 3.5 years of follow-up.