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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Testing in Ontario?

Does anyone know of any facilities that still offer testing for CCSVI In Ontario Canada?
Read more : Testing in Ontario? | Views : 455 | Replies : 4


NEW: Dr. Zamboni's presentation on lymphatic discovery

Dr. Zamboni explains the importance of the most recent discovery from the University of Virginia, published in Nature: which is that a lattice of lymph vessels carrying immune cells are associated with veins flow which out along the cerebral veins into the extracranial veins.

"This is a very important article published in Nature. It is found that it is NOT true that the brain is segregated from the point of view immune system, because it ...
Read more : NEW: Dr. Zamboni's presentation on lymphatic discovery | Views : 781 | Replies : 7


New discoveries show importance of veins

The new discoveries of the lymphatic vessels and immune cells in the CNS and the glymphatic clearance system of the sleeping brain are pointing to the importance of the veins that drain the brain.

Lymphatic vessel drainage runs next to veins, and requires open venous flow, since lymph cells end up in the jugular blood flow.
Really hoping these discoveries move CCSVI research forward.

Here's more on the connection--
http://ccsviinms.blogspot.com/2015/06/a ... ...


Diagnostic accuracy of Doppler sonography and more things

A study from Poland, comparing Doppler and other techniques:

Diagnostic accuracy of Doppler sonography and magnetic resonance venography for the assessmentv of impaired outflow from the internal jugular vein in patients with multiple sclerosis

http://www.termedia.pl/Original-paper-D ... 8,0,1.html

Objectives: This prospective study was aimed at evaluation of diagnostic value of Doppler sonography and magnetic resonance (MR) venography in the internal jugular vein territory.

Material and methods: There were assessed 126 ...
Read more : Diagnostic accuracy of Doppler sonography and more things | Views : 318 | Replies : 1


Sleep Drives Metabolite Clearance from the Adult Brain

http://europepmc.org/articles/pmc3880190
Sleep Drives Metabolite Clearance from the Adult Brain

Lulu Xie,1,* Hongyi Kang,1,* Qiwu Xu,1 Michael J. Chen,1 Yonghong Liao,1 Meenakshisundaram Thiyagarajan,1 John O’Donnell,1 Daniel J. Christensen,1 Charles Nicholson,2 Jeffrey J. Iliff,1 Takahiro Takano,1 Rashid Deane,1 and Maiken Nedergaard1,†


Abstract
The conservation of sleep across all animal species suggests that sleep serves a vital function. We here report that sleep has a critical function in ensuring metabolic homeostasis. Using ...
Read more : Sleep Drives Metabolite Clearance from the Adult Brain | Views : 841 | Replies : 17




Possible pathway: CCSVI -> iron -> Semaphorin4A

A recent article points to the presence of a protein, Semaphorin4A, present in the CSF of people with MS. Nothing new, except because they note that this protein appears because of the iron accumulations. Therefore, I think it is very likely to have it linked to CCSVI

Semaphorin4A Is Cytotoxic to Oligodendrocytes and Is Elevated in Microglia and Multiple Sclerosis.

http://www.ncbi.nlm.nih.gov/pubmed/26024919

We have previously established that T cell immunoglobulin ...
Read more : Possible pathway: CCSVI -> iron -> Semaphorin4A | Views : 354 | Replies : 0


MS: A Case of Poor Plumbing

I believe it will take at least one generation of Doctors, maybe two, to accept the idea that obstruction of the central nervous system fluid circulation is the cause of MS. Neurologists will have to discard the auto-immune theory, and they will have to call on other specialties to treat their patients. In other words, they will have to cede their MS territory.

Even though the Sonograms performed on me by two Parisian Angiologues revealed ...
Read more : MS: A Case of Poor Plumbing | Views : 508 | Replies : 0


Bilateral Sudden Sensorineural Hearing Loss and CCSVI

Just found this on accident. Head scratcher. "CCSVI". Just rolls right off the lips in certain countries I guess...
:?

http://www.pietromariabavera.com/?p=109


Abstract
Objectives: We report a case of bilateral sudden sensorineural hearing loss (SSHL) in a patient suffering from chronic venous cerebrospinal insufficiency (CCSVI). Methods: Audiometric testing confirmed bilateral sensorineural hearing loss with hypoexcitability to caloric stimulation on the left side ...
Read more : Bilateral Sudden Sensorineural Hearing Loss and CCSVI | Views : 354 | Replies : 0


3 new MS drug trials-all address blood flow

Three new MS drug trials in the press this month.

If you ever wondered whether blood flow was important to brain health, all you would have to do is read about three new MS drug trials announced in the past month.

All three of these compounds have been shown in animal models of MS to reduce symptoms, reduce relapses and slow progression. All three have been touted as "neuroprotective."

And all three of these medications ...
Read more : 3 new MS drug trials-all address blood flow | Views : 485 | Replies : 0


 

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