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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

the thing about CCSVI

The thing about CCSVI is that it's obvious in retrospect. Not the link to MS, because that is unproven. But it is only basic logic that anything that can go wrong in the human body does go wrong at least for someone. Hearts get formed wrong, legs go wrong, red blood cells go wrong, retinas go wrong. So the idea that jugular veins can go wrong is only logical. The other obvious concept is that ...
Read more : the thing about CCSVI | Views : 476 | Replies : 2


Hemoglobins as new players in MS

Hemoglobins as new players in multiple sclerosis: metabolic and immune aspects
http://link.springer.com/article/10.100 ... 016-9845-7

Abstract
Basic science investigations and clinical observations in recent years indicate that hemoglobins (Hbs) may have important roles in the pathogenesis of multiple sclerosis (MS). These findings can be summarized as follows: 1- Erythrocyte fragility is higher in MS patients, the released free Hb damages blood-brain barrier, myelin basic protein and also triggers iron overload ...
Read more : Hemoglobins as new players in MS | Views : 541 | Replies : 4




ISNVD will publish one to two books a year

http://www.healalerts.com/article/22204
Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced that it has partnered with the International Society for Neurovascular Disease (ISNVD) to develop and publish an ISNVD-cobranded series of books covering various topics in neurovascular disease. The book series will focus on the latest research in diagnostic and therapeutic modalities for neurovascular disease and its underlying cellular and molecular mechanisms. “We ...
Read more : ISNVD will publish one to two books a year | Views : 312 | Replies : 0


Jugular Vein Obstruction Caused by Turning of the Head

http://www.ajnr.org/content/4/6/1223.full.pdf

Jugular Vein Obstruction Caused by Turning of the Head

by CA Gooding - ‎1983 - ‎Cited by 14 - ‎Related articles

Our studies clearly demonstrated that turning the head to one side results in torsion-compression of the ipsilateral internal jugular vein, which could have hemodynamically significant consequences. Though many collateral channels for venous drainage of the head are available to compensate, they may be severely compromised if resection, ...
Read more : Jugular Vein Obstruction Caused by Turning of the Head | Views : 343 | Replies : 0


Doctoral thesis. Study the Internal Jugular Veins dynamics

A first part of research project was to study the Internal Jugular Veins dynamics in MS patients compared with healthy controls using contrast-enhanced ultrasonography. The patients with MS showed a significantly reduction of wash-out rate compared to healthy controls .

http://www.fedoa.unina.it/10701/
Read more : Doctoral thesis. Study the Internal Jugular Veins dynamics | Views : 356 | Replies : 1


steven novella's article on CCSVI

https://www.sciencebasedmedicine.org/up ... sclerosis/

Any thoughts? We are an echo chamber of denial and belief and that is why doctors, academics, scientists, and science communicators should engage with social media communities? The welcome mat is out for all comers.

Tooth fairy science? He had a valid point, about the need to establish foundational research before moving on to subsidiary concerns, but bringing in the tooth fairy comes across as mocking. ...
Read more : steven novella's article on CCSVI | Views : 427 | Replies : 3


upper jugular stenoses vs lower jugular stenoses

I feel like this is an important aspect that may be being disregarded. Here are two research articles published this year that looked specifically at patients WITHOUT multiple sclerosis:
http://link.springer.com/article/10.100 ... 016-4314-6
http://www.ajronline.org/doi/abs/10.2214/AJR.15.14689

and a quote from each:
Both observers found stenosis in the IJVs with fair agreement. Most stenoses were located in the upper IJV segments.
Areas of narrowing greater than 50% ...
Read more : upper jugular stenoses vs lower jugular stenoses | Views : 346 | Replies : 0


MS and primary vascular dysregulation

https://www.ncbi.nlm.nih.gov/pubmed/27307797
EPMA J. 2016 Jun 15;7:13. doi: 10.1186/s13167-016-0062-6. eCollection 2016.

Multiple sclerosis and primary vascular dysregulation (Flammer syndrome).

Konieczka K1, Koch S1, Binggeli T1, Schoetzau A1, Kesselring J2.
Author information

Abstract
BACKGROUND:
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS of still unknown aetiology. Flammer syndrome (FS) encompasses a set of symptoms and signs that are primarily but not solely related to the dysregulation of blood ...
Read more : MS and primary vascular dysregulation | Views : 354 | Replies : 0


vascular problems also found in the retina

The retina and the optic nerve are the only extensions of the CNS that can be observed non-invasive. The retina in MS is known to degenerate and is unknown how, as there is no myelin on the retina and current MS models do not explain this problem.

Two new articles have found that retinal degeneration is linked to blood flow problems in the eye.

I would challenge any supporter of the autoimmune model to explain ...
Read more : vascular problems also found in the retina | Views : 372 | Replies : 3


 

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