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A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

astronaut eyes

More information on the damage to astronaut eyes during long term spaceflight. It was on CNN's website so probably fake news. Just kidding. Thought this was interesting, the idea that eyes act like a pressure release valve to a brain that has too much cerebrospinal fluid pressure.

http://www.cnn.com/2017/11/01/health/br ... index.html

Given the connection between the eye, the optic nerve and the brain, combined with the fluid shift astronauts experience, ...
Read more : astronaut eyes | Views : 628 | Replies : 1


Could it be that CCSVI just makes MS worse?

Could it be that CCSVI just makes MS worse?

This is an idea that came to me after reading an article named "The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766379/). I enclose here some quotes:

"Their location (of the lesions), shape and patterns of active demyelination are compatible with the view that they are driven by a soluble factor, produced in the inflammatory infiltrates of ...
Read more : Could it be that CCSVI just makes MS worse? | Views : 855 | Replies : 6


vascular impact in brain volume and lesion load

The impact of vascular risk factors on brain volume and lesion load in patients with early multiple sclerosis

http://journals.sagepub.com/doi/abs/10. ... 8517736149

Conclusion:

VRF are associated with lower brain volume already in early MS but do not lead to increased brain volume loss during 3.5 years of follow-up.
Read more : vascular impact in brain volume and lesion load | Views : 556 | Replies : 0




brain drain

https://www.nih.gov/news-events/news-re ... our-brains

The question in my mind is: is it nocturnal (i.e. during REM sleep). If it is, (the mice drained during diurnal sleep -- i.e., during the day) we may have a way to deal with Alzheimers -- by getting good sleep!

In fact, it should be a goal of the makers of sleeping medication to trigger the brain's "rinse cycle". Are you listening, drug manufacturers?
Read more : brain drain | Views : 868 | Replies : 5


New association of vein anomalies and MS found, Sept. 2017

New association of vein anomalies and MS found, Sept. 2017. I put the date because this has been reported already before.

I would say that is getting clear that MS is not a single disease. Some cases are clearly of vascular origin, though some others are not. Look at this.

Association of Developmental Venous Anomalies with Demyelinating Lesions in Patients with Multiple Sclerosis

http://www.ajnr.org/content/early/2017/09/14/ajnr.A5374

SUMMARY: We present 5 cases ...
Read more : New association of vein anomalies and MS found, Sept. 2017 | Views : 569 | Replies : 0


Vascular hypoperfusion in acute optic neuritis

Vascular hypoperfusion in acute optic neuritis is a potentially new neurovascular model for demyelinating diseases.

Source: https://www.ncbi.nlm.nih.gov/pubmed/28926646

Abstract
PURPOSE:

Optic neuritis is highly correlated with multiple sclerosis and is a major cause of acute visual loss and long-term neuronal degeneration. Primary cerebral hypoperfusion has been reported in brain demyelinating diseases. This study investigated whether peripapillary perfusion is changed in patients with acute optic neuritis (AON).
METHODS:

This three-year cohort ...
Read more : Vascular hypoperfusion in acute optic neuritis | Views : 572 | Replies : 0


Association of Developmental Venous Anomalies with MS

Association of Developmental Venous Anomalies with Demyelinating Lesions in Patients with MS

Source: https://www.ncbi.nlm.nih.gov/pubmed/28912286

Abstract

We present 5 cases of demyelination in patients diagnosed with multiple sclerosis that are closely associated with a developmental venous anomaly.

Although the presence of a central vein is a known phenomenon with multiple sclerosis plaques, demyelination occurring around developmental venous anomalies is an underreported phenomenon.

Tumefactive demyelination can cause a diagnostic dilemma because ...
Read more : Association of Developmental Venous Anomalies with MS | Views : 624 | Replies : 2


The central vein sign

The CVS (Central Vein Sign) is an unmistakeable indication of MS. I expect it is an unmistakeable sign of CCSVI as well. Prevalence studies in future, as well as particular studies of MS treatments, should all use this sign as a definite verification of the presence of MS. There may be ways to measure changes to this sign to indicate efficacy of MS treatments.



The central vein sign and its clinical evaluation for the diagnosis ...
Read more : The central vein sign | Views : 929 | Replies : 4


Inversion?

For the past ten years I've used The Back Revolution, an inversion device designed to decompress lumbar discs: https://www.inversionusa.com/Bent-Knee- ... stems.html Could this work with CCSVI?
Read more : Inversion? | Views : 646 | Replies : 1


 

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