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Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome.
Reed-Cossairt A, Zhu X, Lee HG, Reed C, Perry G, Petersen RB
Zhu/Lee Lab (Case Western Reserve University)
Curr Gerontol Geriatr Res. 2012 . 2012():929734.
Down syndrome (DS) individuals are at high risk for developing Alzheimer's disease (AD) and consequently provide a unique opportunity to examine the factors leading to the ...
Brain and spinal cord revascularization by omental transposition.
Department of Neurosurgery, Boston University School of Medicine, MA 02118.
It has been learned over the years that placement of the pedicled omentum onto the brain and the spinal cord results in the rapid development of blood vessels ...
Jugular venous reflux and brain parenchyma volumes in elderly patients with mild cognitive impairment and Alzheimer's disease
Clive Beggs, Chih-Ping Chung, Niels Bergsland, Pei-Ning Wang, Simon Shepherd, Chun-Yu Cheng, Michael G Dwyer, Han-Hwa Hu and Robert Zivadinov
BMC Neurology 2013, 13:157 doi:10.1186/1471-2377-13-157
Published: 31 October 2013
To determine whether or not jugular venous reflux (JVR) is associated with structural brain parenchyma changes in individuals with mild cognitive impairment (MCI) and Alzheimer's disease ...
Veteran Kikuyu singer and producer Julius Kang'ethe, popularly known as Bylaw, is appealing to well-wishers to help him raise funds to seek specialised medical care in India.
The 54-year-old musician, who burst into fame in the 1980s, was diagnosed with Multiple Sclerosis in 2009. It is an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
Famed for his ...
A dynamic ECD approach allowed us to detect IJVs with a significant increase in their CSAs during head rotation, but only in MS subjects. This feature, most likely the expression of congenital wall miopragia, could be secondary to dysregulation of collagen synthesis, but further histochemical studies will be needed to confirm this hypothesis.
Fig. 1 (a) Hypothetical illustration of the blood flowing through an artery (or arteriole), capillaries and a vein (or venule), subsequently, in the condition of intact BBB. (b) Same representation for a compromised blood brain barrier, wherein the venous output (red arrow) is decreased. The input and output blood volumes are represented by white and red arrows, respectively. (c) Hypothetical transverse velocity profile along the ...
“It’s remarkable that venular caliber in the eye is related, however modestly, to mental test scores of individuals in their 30s, and even to IQ scores in childhood,” Dr Idan Shalev and colleagues said.
The findings suggest that the processes linking vascular health and cognitive functioning begin much earlier than previously assumed, years before the onset of dementia and other age-related declines in brain functioning.
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