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News News of Drug Pipeline

Site map of Drug Pipeline » Forum : Drug Pipeline

A board to discuss future MS therapies in early stage (Phase I or II) trials.

 [ Total topics 744 Go to page 1, 2, 3, 4, 5 ... 75

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 Post subject: Has anyone here had BOTOX injections in the bladder ?
PostPosted: Thu Feb 07, 2013 2:09 pm 
a uro-neurologist has offered me this treatment option of having BOTOX injections in the bladder to improve bladder incontinence symptoms,
he said it improves MS patients urgency, frequency and control of their bladder,
you are under a local anaesthetic for 45 minutes during the injections, and the effects last 6-12 months before requiring further injections,

this 'trial' seems promising and as i have this option for treatment am very tempted to go ahead with the ...

Read more : Has anyone here had BOTOX injections in the bladder ? | Views : 533 | Replies : 3

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 Post subject: Neurosteroids
PostPosted: Wed Feb 06, 2013 7:34 am 
It is older story, but might merit more attention as hormon levels can be adjusted even without a new drug:

"Studies in EAE mice showed reduced neurosteroid levels in their brains. Intraperitoneal
injections of allopregnanolone in mice shortly after induction of EAE led to improvements in several
markers of disease, relative to sham-treated animals.

These included:
Preserved myelin in the spinal cord
Reduced reactivity in immune cells
Lower immunoreactive cell counts in the spinal cord ...

Read more : Neurosteroids | Views : 393 | Replies : 0

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 Post subject: Amiloride
PostPosted: Sat Feb 02, 2013 7:45 am 
Anyone tried Amiloride? Any experience with i? As it is already a cheap prescription drug with safe track record and with great potential for progressive patients, I would have assumed that some doctors might have prescribed it or someone tried it.

Quote:
Amiloride study in Multiple Sclerosis wins national award

This week the Multiple Sclerosis (MS) research team at University of Oxford was awarded the prestigious MS Research Project of the Year award. The award was ...

Read more : Amiloride | Views : 716 | Replies : 4

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 Post subject: MSRV Retrovirus, phase 2
PostPosted: Thu Dec 20, 2012 4:05 pm 
Hello everybody :smile:

I am involved in the following study, described hereafter.

Mister Hervé Perron, who found the retrovirus, gave more details here : http://www.forseps.org/t1921-reponses-sur-le-retrovirus (in French), and you can follow my experience regarding this test here : http://www.forseps.org/t1920-fred1208-geneve (in French).

Source http://www.bioworld.com :

Spun out in 2006 from ...

Read more : MSRV Retrovirus, phase 2 | Views : 1713 | Replies : 15

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 Post subject: Phenytoin
PostPosted: Sun Dec 09, 2012 7:59 am 
Not sure if this has been posted elsewhere.

http://www.youtube.com/watch?v=Y3s4mOTc ... ture=share

Read more : Phenytoin | Views : 582 | Replies : 0

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 Post subject: low t
PostPosted: Wed Dec 05, 2012 11:12 am 
http://www.colbertnation.com/the-colber ... -t---low-o

or :-D

http://www.thecomedynetwork.ca/shows/Th ... age=127831

Read more : low t | Views : 478 | Replies : 0

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 Post subject: BG 12
PostPosted: Fri Nov 30, 2012 6:28 pm 
Hey Dig, long time. What is your latest take on BG12? Is this really fumeric acid? All my Neuros seem to think its the Holy Grail but if we can just do it ourselves why would anyone sign on for a high dollar Med? Rituxan coming up hard and fast!
Lars

Read more : BG 12 | Views : 1234 | Replies : 8

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 Post subject: Wow-too good to be true? Nanotechnology
PostPosted: Sun Nov 18, 2012 2:36 pm 
http://www.eurekalert.org/pub_releases/ ... 111312.php

Read more : Wow-too good to be true? Nanotechnology | Views : 1152 | Replies : 1

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 Post subject: Nuron closing in on new treatment for relapsing MS
PostPosted: Wed Nov 14, 2012 3:27 am 
Image

Nuron Biotech Inc. said Tuesday it has completed enrollment of 500 patients for a pivotal phase-III study evaluating the safety and effectiveness of the company’s experimental multiple sclerosis treatment.

Phase-III studies are typically the last hurdle a drug developer must clear before seeking approval for a new drug candidate.

Nuron, an Exton, Pa., specialty biologics and vaccines company, is developing NU100 to treat relapsing remitting multiple sclerosis.

Shankar Musunuri, the company’s founder and CEO, ...

Read more : Nuron closing in on new treatment for relapsing MS | Views : 717 | Replies : 1

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 Post subject: MIS 416 - Phase 2 interim results
PostPosted: Mon Aug 20, 2012 8:44 am 
" AUCKLAND, New Zealand--(BUSINESS WIRE)--

Innate Immunotherapeutics today announced positive interim data from the company’s Phase 1/2 clinical trial of MIS416 in patients with chronic progressive multiple sclerosis (MS). Results of the open-label, dose-escalation/confirmation trial showed MIS416 to be well tolerated and identified a clinical dose for further evaluation. Moreover, during the dose confirmation portion of the study, 8 of 10 patients with secondary progressive MS who were treated with MIS416 for 12 weeks showed ...

Read more : MIS 416 - Phase 2 interim results | Views : 1014 | Replies : 0

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