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A board to discuss future MS therapies in early stage (Phase I or II) trials.

ibudilast

Ibudilast (development codes: AV-411 or MN-166) is an antiinflammatory drug used mainly in Japan, which acts as a phosphodiesterase inhibitor, inhibiting the PDE-4 subtype to the greatest extent, but also showing significant inhibition of other PDE subtypes.
Ibudilast has bronchodilator, vasodilator and neuroprotective effects, and is mainly used in the treatment of asthma and stroke. It inhibits platelet aggregation, and may also be useful in the treatment of multiple sclerosis.
Ibudilast crosses the blood–brain ...
Read more : ibudilast | Views : 738 | Replies : 0


Testosterone

Testosterone in women with MS is significantly lower than a healthy subject. On the flip side of this too much testosterone in a female MS patient causes irreversible brain damage during a relapse. This is why it is thought that while men get MS less often they typically have a more progressive and debilitating form of it.

The sex hormone level results were different for the men with little change between controls and MS patients. ...
Read more : Testosterone | Views : 810 | Replies : 2


Fecal microbiota transplantation

Its gross, no doubt, but the science behind "poop transplants" is starting to turn heads in the medical community. For MS it really speaks to the idea that gut bacteria makes a big difference in disease progression.

"...Whilst using FMT (fecal microbiota transplantation) to treat ulcerative colitis or constipation-predominant IBS in the Sydney clinic, serendipitous improvements in extraintestinal conditions not previously considered to be microbiota-related have also been observed. These include the virtually complete and ...
Read more : Fecal microbiota transplantation | Views : 845 | Replies : 2


PARKINSONS DRUG FOR TREATING M.S

THE DRUG BENZTROPINE WAS TRAIL FOR TREATING M.S DETAILS PLEASE READ THE WEB SITE
http://www.medicaldaily.com/parkinsons- ... ent-259364
regards
seeva :roll:
Read more : PARKINSONS DRUG FOR TREATING M.S | Views : 1087 | Replies : 3


Rosiglitazone

Has anybody tried Rosiglitazone (diabetes drug) for the treatment of nerve pain? It blocks the PPAR-gamma. Whatever that means.
Read more : Rosiglitazone | Views : 638 | Replies : 0


Is Myrbetriq/Betmiga any good for MS overactive bladder?

Hi,

I had botox in the bladder 5 monthsago but it is wearing off now
so i am going to take a medicine until my next botox, which should be January/February

Before i used to take 1x 60mg TROSPIUM before bed, but my nurse said there another drug i might want to try called Betmiga 50mg once daily.

Has anyone tried Myrbetriq / Betmiga 50mg once daily?

if so, how do you find it? how ...
Read more : Is Myrbetriq/Betmiga any good for MS overactive bladder? | Views : 885 | Replies : 0


MEDICAL MAFIA

MEDICAL MAFIA/CPS & CORRUPT JUSTICE SYSTEM RE: UTAH BOY WHO HAD NO CANCER:
http://vaccineliberationarmy.com/2013/1 ... no-cancer/
Regards
Rici
Read more : MEDICAL MAFIA | Views : 719 | Replies : 1


GALECTINS ONE CLOSE STEP FORWARD TO REMYELINATION

GALECTINS IN ARGENTINA ONE CLOSE STEP FORWARD TO REMYELINATION


Galectin-3 controls the response of microglial cells to limit
cuprizone-induced demyelination.


Hoyos HC, Rinaldi M, Mendez-Huergo SP, Marder M, Rabinovich GA, Pasquini JM, Pasquini LA.

Source
Department of Biological Chemistry, School of Pharmacy and Biochemistry, University of Buenos Aires and National Research Council (CONICET), Argentina; Institute of Chemistry and Biological Physicochemistry (IQUIFIB), School of Pharmacy and Biochemistry, University of Buenos Aires and National Research Council ...
Read more : GALECTINS ONE CLOSE STEP FORWARD TO REMYELINATION | Views : 916 | Replies : 0


Positive top-line phase II results of Ofatumumab in MS

Genmab A/S announced top-line results from a Phase II study of the subcutaneous formulation of
ofatumumab in relapsing-remitting multiple sclerosis (RRMS).

A total of 232 subjects with RRMS were randomized in the study. There was a
clear separation from placebo on the cumulative number of new gadolinium
enhancing lesions (active brain lesions) over a period of 12 weeks in subjects
treated with all doses of ofatumumab compared to subjects treated with placebo
. ...
Read more : Positive top-line phase II results of Ofatumumab in MS | Views : 968 | Replies : 0


NEW DRUG FOR REPAIR DAMAGED MYELIN

NEW DRUG PHASE 1 CLINICAL STUDY FOR REPAIR MYELIN DAMAGED BY PROGRASIVE M.S PLEASE SEE THE DETAILS
http://www.news-medical.net/news/201304 ... rosis.aspx
regards
seeva :twisted:
Read more : NEW DRUG FOR REPAIR DAMAGED MYELIN | Views : 1748 | Replies : 1


 

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