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News News of Drug Pipeline

Site map of Drug Pipeline » Forum : Drug Pipeline

A board to discuss future MS therapies in early stage (Phase I or II) trials.

 [ Total topics 744 Go to page 1, 2, 3, 4, 5, 6, 7 ... 75

Message
 Post subject: "Discovery could halt MS progression"
PostPosted: Thu Apr 26, 2012 4:34 am 
Any Ideas what this is about?
http://www.heraldsun.com.au/news/breaking-news/discovery-could-halt-ms-progression/story-e6frf7jx-1226338953415
Quote:
MELBOURNE researchers may have found a way to block the progression of multiple sclerosis (MS).

Blocking a specific protein responsible for nerve damage acted as a hand brake to progression of the disease, researchers from RMIT and Monash Universities have discovered.

The findings, published this week in the international journal Brain, could provide hope to sufferers of MS, one of the world's most common neurological diseases.

...

When ...

Read more : "Discovery could halt MS progression" | Views : 1887 | Replies : 3

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 Post subject: Monthly Treatment vs Orals
PostPosted: Thu Apr 19, 2012 3:48 pm 
I read that soon (1-2 years) a new long acting interferon beta will be on the market that will require only one monthly injection. The adverse events seem to be limited only to the days after the injection so one will be able to have the rest of the month without side effects. If it turns out to be true, would you switch to this new product? Thoughts on a monthly interferon vs the other ...

Read more : Monthly Treatment vs Orals | Views : 903 | Replies : 1

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 Post subject: How to taper a medicine?
PostPosted: Thu Mar 15, 2012 3:28 am 
Hey fellas;

Not sure I am using the correct word but I'll try...

I am currently taking Methotrexate 3X10mg/week since quite a long time. It possibly helped (no one knows) because since a while I have no more active lesions. Therefore I'd like to reduce its consumption since I believe the less chemical the better.

Question (request for opinion) is: is it better to change the frequency (like 2X10mg/week) or the dosage (still 3Xweek but ...

Read more : How to taper a medicine? | Views : 905 | Replies : 2

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 Post subject: Periodic steroid infusions may stabilize/improve PPMS
PostPosted: Sun Feb 12, 2012 5:29 am 
It is an old article back in 2008, but I am wondering if anyone knows how it stands today. Anyone with ppms has tried such a regimen of steroids?

Quote:
The dose of MP was 30 mg/kg in 250 mL of glucose solution in three consecutive days during the first week, two doses during the second and one dose in the third week. One weekly session for eight consecutive weeks was given. After, a once-a week/eight-week ...

Read more : Periodic steroid infusions may stabilize/improve PPMS | Views : 2017 | Replies : 10

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 Post subject: What happened to RTL 1000?????
PostPosted: Sun Feb 12, 2012 3:31 am 
Anyone knows what happened to RTL 1000? They completed the Phase 1 of the clinical trials more than 2 years ago, back in the fall of 2009 and since then there is no Phase 2 initiated. Would it take years to start Phase 2 after successfully completing Phase 1? 2 years ago Al Ferro, President and CEO of Artielle ImmunoTherapeutics, Inc. said that "We plan to move aggressively to bring these novel, first-in-class products to ...

Read more : What happened to RTL 1000????? | Views : 1402 | Replies : 2

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 Post subject: have u heard of these med's ( NEW TO THE SITE )
PostPosted: Sat Jan 14, 2012 3:13 pm 
:-D
Eveing to all i have a severe reaction to cannulas so i can only take tablet's so i trying to nhs fundind for the new ms drug's which are quite rare in the uk some not

bg12 , leustat, fingolimod, laquinmod, teriflunomide and i also take a parkinson drug for circulation and cramp's roprinole which is fab no side effect's so far

look forward to ...

Read more : have u heard of these med's ( NEW TO THE SITE ) | Views : 1821 | Replies : 2

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 Post subject: Researchers in Canada have discovered a potential new drug
PostPosted: Thu Oct 27, 2011 8:35 am 
http://www.sciencedaily.com/releases/20 ... +Health%29

Read more : Researchers in Canada have discovered a potential new drug | Views : 1655 | Replies : 0

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 Post subject: Alemtuzumab (Campath): Phase III Results
PostPosted: Tue Oct 25, 2011 3:06 pm 
Antibody offers hope for multiple sclerosis treatment
Promising phase III trial paves the way for alemtuzumab approval.
Published online 24 October 2011: Nature

http://www.nature.com/news/2011/111024/ ... 1.609.html


The first drug to show signs of not just halting multiple sclerosis (MS), but actually reversing the nerve damage caused by the condition, has taken a significant step towards clinical approval.

The results of a phase III trial, presented on 22 October at ...

Read more : Alemtuzumab (Campath): Phase III Results | Views : 1493 | Replies : 0

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 Post subject: MS Non-Placebo, Comparative Clinical Trial now enrolling
PostPosted: Wed Oct 05, 2011 10:47 am 
I am reaching out to my community contacts to spread the word about a newly enrolling research study for Multiple Sclerosis in Atlanta, Georgia (other sites are also conducting this study in other parts of the country). The study will last 96 weeks and will consist of only 11 office visits. This particular MS study may be advantageous to potential participants because it is a comparison study rather than a placebo study. This means that ...

Read more : MS Non-Placebo, Comparative Clinical Trial now enrolling | Views : 1208 | Replies : 0

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 Post subject: Curing MS (in EAE mice) with Glucosamine
PostPosted: Fri Sep 30, 2011 12:31 pm 
Glucosamine-like supplement suppresses multiple sclerosis attacks

UCI study shows promise of metabolic therapy for autoimmune diseases

Irvine, Calif., Sept. 30, 2011 — A glucosamine-like dietary supplement suppresses the damaging autoimmune response seen in multiple sclerosis, according to a UC Irvine study.

UCI's Dr. Michael Demetriou, Ani Grigorian and others found that oral N-acetylglucosamine (GlcNAc), which is similar to but more effective than the widely available glucosamine, inhibited the growth and function of abnormal T-cells that ...

Read more : Curing MS (in EAE mice) with Glucosamine | Views : 1967 | Replies : 3

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 [ Total topics 744 Go to page 1, 2, 3, 4, 5, 6, 7 ... 75


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