It is currently Mon Dec 22, 2014 4:15 am

News News of Drug Pipeline

Site map of Drug Pipeline » Forum : Drug Pipeline

A board to discuss future MS therapies in early stage (Phase I or II) trials.

HSCT

Like many I want to halt this curse until some better treatments come along. I share the views of this guy who posted on the BCP site:


HSCT

This procedure is very efficious on early RRMS patients, when inflammation dominates. As the spectrum shifts from inflammatory in nature to progressive, it becomes less effective. It is not at all effective for primary progressive MS. Data suggest inflammation is held in check for at least 5-6 ...
Read more : HSCT | Views : 1337 | Replies : 0


MS drugs

Dear all,

The UK has an MS website called MSRC. They have a list of drugs (licenced and it trial) on the site. The list isn't anywhere near as comprehensive as Dignans, but when you click on each drug there is a link to press articles etc.

Tovaxin, Neurovax and Rituximab look the best of the bunch to me.

http://www.msrc.co.uk/index.cfm?fuseact ... N=57563484

Ian
Read more : MS drugs | Views : 1991 | Replies : 4


ACTS

Read more : ACTS | Views : 1152 | Replies : 0


Rituximab

Read more : Rituximab | Views : 1321 | Replies : 0


Rituxan Phase III for PPMS

I thought this was a typo a week or two ago when I saw mention of the latest Rituxan trial for PPMS being a Phase III trial, but this exerpt from a press release today says it again, so I guess it's not a typo.



Genentech Announces Full Year and Fourth Quarter 2005 Results

Tuesday January 10, 4:29 pm ET

Record Annual Revenues of $6.6 Billion Drive Year-Over-Year Non-GAAP EPS Growth of 54 Percent

SOUTH ...
Read more : Rituxan Phase III for PPMS | Views : 1582 | Replies : 0


HP184

Here's a drug (Sanofi-aventis' HP184) in the early stages that might be helpful for MS and other conditions.



Tireless quest for a cure, Lorenzo-style

Globe & Mail - January 9, 2006...

Of particular interest is a drug called HP184, a sodium and potassium channel blocker that has been tested on spinal cord patients. When Jacob's parents brought the drug, made by Sanofi-aventis, to the attention of doctors, none had heard of it.

"They're very proactive, ...
Read more : HP184 | Views : 2222 | Replies : 1


A new angle: using RNA

This sounds like a different way of treating MS that has potential.



A Novel Method of Modifying Immune Responses By Vaccination With Lipiodol-siRNA Mixtures.

J Transl Med. 2006 Jan 3;4(1):2
Ichim TE, Popov IA, Riordan NH, Izadi H, Zhong Z, Yijian L, Sher S, Oleinik EK.

ABSTRACT: The dendritic cell (DC) possesses the ability to stimulate both T helper 1 (Th1) and Th2 responses depending on activation stimuli. Although it is ...
Read more : A new angle: using RNA | Views : 1181 | Replies : 0




EPO

EPO is in pre-clinical studies for MS. This abstract talks about a modified version that would possibly have fewer side effects...



Delayed administration of erythropoietin and its non-erythropoietic derivatives ameliorates chronic murine autoimmune encephalomyelitis.

J Neuroimmunol. 2005 Dec 6;
Savino C, Pedotti R, Baggi F, Ubiali F, Gallo B, Nava S, Bigini P, Barbera S, Fumagalli E, Mennini T, Vezzani A, Rizzi M, Coleman T, Cerami A, Brines M, Ghezzi P, Bianchi R.
"Mario Negri" ...
Read more : EPO | Views : 1408 | Replies : 0


Nutra Pharma Reports Discovery of New Gene Involved in MS

This came out today!


BOYNTON BEACH, Fla.--(BUSINESS WIRE)--Dec. 19, 2005--Nutra Pharma Corp., (OTCBB:NPHC) a biotechnology holding company that owns rights to intellectual property related to the development of drugs for HIV and Multiple Sclerosis (MS) has announced that their continuing microarray studies have identified a new gene involved in the disease process of Multiple Sclerosis. Although the gene and some of its functions are already known, this is the first evidence of involvement with the ...
Read more : Nutra Pharma Reports Discovery of New Gene Involved in MS | Views : 1272 | Replies : 0


 

Login  •  Register


Statistics

Total posts 222343 • Total topics 23093 • Total members 14620


Contact us | Terms of Service