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Gene involvement in mechanisms of neurodegeneration.....

Gene involvement in mechanisms of neurodegeneration and neuroinflammation

Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study.

Durrenberger PF, Fernando FS, Kashefi SN, Bonnert TP, Seilhean D, Nait-Oumesmar B, Schmitt A, Gebicke-Haerter PJ, Falkai P, Grünblatt E, Palkovits M, Arzberger T, Kretzschmar H, Dexter DT, Reynolds R.

Abstract

Neurodegenerative diseases of the central nervous system are characterized by pathogenetic cellular and molecular changes in specific areas of the brain that lead ...
Read more : Gene involvement in mechanisms of neurodegeneration..... | Views : 219 | Replies : 0


Nerve conduction velocity gene linked to multiple sclerosis

Evidence found in both human multiple sclerosis patients and experimental mouse models, according to research published in the American Journal of Pathology.

A new study published in The American Journal of Pathology identifies a novel gene that controls nerve conduction velocity. Investigators report that even minor reductions in conduction velocity may aggravate disease in multiple sclerosis (MS) patients and in mice bred for the MS-like condition experimental autoimmune encephalomyelitis (EAE)...... Read more- http://www.ms-uk.org/genetics
Read more : Nerve conduction velocity gene linked to multiple sclerosis | Views : 313 | Replies : 1


Multiple sclerosis discovery may explain gender gap

A key difference in the brains of male and female MS patients may explain why more women than men get the disease, a study suggests.

Scientists at Washington University School of Medicine in the US found higher levels of protein S1PR2 in tests on the brains of female mice and dead women with MS than in male equivalents.....Read More - http://www.ms-uk.org/genetics
Read more : Multiple sclerosis discovery may explain gender gap | Views : 2112 | Replies : 0


Genome study identifies three possible drug candidates...

Genome study identifies three possible drug candidates for autoimmune diseases

New pharmaceuticals to fight autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis and psoriasis, may be identified more effectively by adding genome analysis to standard drug screening, according to a new study by a research team led by UC San Francisco and Harvard researchers, in collaboration with Tempero and GlaxoSmithKlein.

In a study reported online April 17, 2014 in the journal Immunity, the scientists combined ...
Read more : Genome study identifies three possible drug candidates... | Views : 428 | Replies : 1


Researchers testing gene therapy to thwart effects of MS

In patients with multiple sclerosis, the body turns on itself, launching an immune system attack that destroys the coating around nerve fibers in the central nervous system, leaving them exposed like bare wires. Similar to exposed electrical lines, the unprotected fibers touch and short out, leading to the neurodegenerative effects that are a hallmark of multiple sclerosis...... Read More - http://www.ms-uk.org/genetics
Read more : Researchers testing gene therapy to thwart effects of MS | Views : 538 | Replies : 0


Positive clinical performance of MSPrecise

DioGenix reports positive clinical performance of molecular diagnostic MSPrecise for Multiple Sclerosis

DioGenix, Inc. announced today new data supporting the clinical validation of MSPrecise®, its proprietary next-generation sequencing (NGS) assay for the identification of patients with multiple sclerosis (MS) at first clinical presentation. The prospective study met its primary endpoint by demonstrating the ability of MSPrecise to diagnose patients with MS. The test performed consistently with previous clinical studies, having a specificity of 82% while ...
Read more : Positive clinical performance of MSPrecise | Views : 662 | Replies : 0


Researchers assess familial risks for MS ......

Researchers assess familial risks for MS using population registers, health care registries

Even though multiple sclerosis is largely caused by genetic factors, the risk of patients' relatives developing the disease is lower than previously assumed. This is the conclusion of a new population registry-based study, published in the scientific journal Brain...... Read More - http://www.ms-uk.org/genetics
Read more : Researchers assess familial risks for MS ...... | Views : 437 | Replies : 0


MS research appeal

An Orcadian geneticist who is researching the causes of MS in the Northern Isles, is asking people in Orkney to help create a list of all the people with Orkney and Shetland ancestors who have had Multiple Sclerosis.

Dr Jim Wilson who works for the Centre for Population Health Services at the University of Edinburgh said it is important to work out the degree to which MS is genetic in Orkney and Shetland, through building ...
Read more : MS research appeal | Views : 389 | Replies : 0


Mapping reveals 110 multiple sclerosis risk genes

Norwegian researchers have mapped genetic variations associated with an increased risk of multiple sclerosis (MS) and myasthenia gravis (MG), bringing science one step closer to understanding these serious autoimmune disorders.

The Norwegian researchers have taken part in an international cooperative effort to map 110 genetic variations that increase the risk of MS and MG. Most of these genetic variations have been mapped in recent years.......Read More - http://www.ms-uk.org/genetics
Read more : Mapping reveals 110 multiple sclerosis risk genes | Views : 511 | Replies : 0


Genetic breakthrough brings scientists closer to M.S. cure

A DR. DAVID BOOTH FROM WESTMEAD GENTIC STUDIES FINDS VERY CLOSE TO IDENTIFIED THE GENES ASSOSIATED WITH M.S MORE DETAILS FROM THE WEB SITE http://www.abc.net.au/news/2013-09-30/b ... re/4987984
REGARDS
SEEVA :roll:
Read more : Genetic breakthrough brings scientists closer to M.S. cure | Views : 8732 | Replies : 1


 

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