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A mutation increases 70% the risk of multiple sclerosis!

This is the first genetic alteration associated with less frequent familial cases.

A mutation in the gene NR1H3 increases by 70% the risk of developing multiple sclerosis, as described today in Neuron by a team from the University of British Columbia in Vancouver (Canada).
Here is the link:
http://www.cell.com/neuron/fulltext/S08 ... %2930126-X
Read more : A mutation increases 70% the risk of multiple sclerosis! | Views : 356 | Replies : 3


New gene being linked to multiple sclerosis

Researchers have discovered a gene involved in deregulation of certain immune cells in multiple sclerosis...Read more - http://www.ms-uk.org/MSnews
Read more : New gene being linked to multiple sclerosis | Views : 227 | Replies : 0


Gene expression between men and women differs during relapse

Gene expression between men and women differs during relapse and remission in MS

A new study in Spain has highlighted differing patterns of small non-coding RNA (sncRNA) molecules regulate relapse and remission in multiple sclerosis and that this differs between men and women...Read more - http://www.ms-uk.org/MSnews
Read more : Gene expression between men and women differs during relapse | Views : 758 | Replies : 0


MS resistance traced to a gene variant in Colombia

A Colombian study has reported finding an increased risk of multiple sclerosis (MS) associated with a particular allele, or gene variant, in a group of patients from the Colombian capital, Bogotá...Read more - http://www.ms-uk.org/MSnews
Read more : MS resistance traced to a gene variant in Colombia | Views : 643 | Replies : 0


Discovering a ‘new world’ in MS through Genomics

A Satellite Symposia entitled Discovering A New World in MS supported by Teva Neuroscience has been held at the 31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), currently taking place in Barcelona, Spain... Read more - http://www.ms-uk.org/MSnews
Read more : Discovering a ‘new world’ in MS through Genomics | Views : 1047 | Replies : 0


New genetic risk factors identified

Two new risk factors for multiple sclerosis have been identified by a research group at the Wellcome Trust Centre for Human Genetics at the University of Oxford in the United Kingdom.... Read More - http://www.ms-uk.org/genetics
Read more : New genetic risk factors identified | Views : 986 | Replies : 0


Identifying MS gene mutations could lead to personalised....

Identifying MS gene mutations could lead to personalised treatments

Personalised medicine, often applied to treat cancer, may be possible for patients with multiple sclerosis as well. Certain patients respond differently to certain multiple sclerosis medications, such as interferon-β (IFNβ), and researchers at San Raffaele Scientific Institute in Milan may have an answer as to why.... Read More - http://www.ms-uk.org/genetics
Read more : Identifying MS gene mutations could lead to personalised.... | Views : 1213 | Replies : 0


Gene that "triggers" multiple sclerosis identified

New research identifies a pivotal gene in multiple sclerosis, linking it to the most important genetic factor that drives the condition..... Read More - http://www.ms-uk.org/genetics
Read more : Gene that "triggers" multiple sclerosis identified | Views : 1152 | Replies : 0


Researcher improves methodology ......

Researcher improves methodology for predicting genetic ‘mutations’

Researchers around the world have sequenced the genomes of patients living with from common, multi-gene diseases, looking for common mutations in their control regions. However these studies produce hundreds of mutations, many of which prove to be benign..... Read More - http://www.ms-uk.org/genetics
Read more : Researcher improves methodology ...... | Views : 855 | Replies : 0


Gene linked to interferon-beta treatment

A new study led by investigators at Brigham and Womens Hospital (BWH) reports the discovery of a genetic variant associated with a patients likelihood of responding to interferon-beta, one of the medications used in treating multiple sclerosis...... Read More - http://www.ms-uk.org/genetics
Read more : Gene linked to interferon-beta treatment | Views : 1005 | Replies : 0


 

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