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A forum to post questions, answers and discussion about general medications not specifically for multiple sclerosis, such as prednisone, painkillers, etc.

Metformin for treatment of multiple sclerosis?

Seems like Metformin does all the right things to treat MS.


J Immunol. 2009 Jun 15;182(12):8005-14. doi: 10.4049/jimmunol.0803563.

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis.

Nath N, Khan M, Paintlia MK, Singh I, Hoda MN, Giri S

J Immunol. 2009 Sep 1;183(5):3551. Singh, Inderjit .

Experimental autoimmune encephalomyelitis (EAE) is a T cell-mediated autoimmune disease of the CNS. Metformin is the most widely used drug ...
Read more : Metformin for treatment of multiple sclerosis? | Views : 2421 | Replies : 1

Klonopin (clonozapam) for spasticity?

Does anyone take Klonopin for spasticity?

My neuro told me to try 0.5mg at bedtime to help my leg stiffness since I can't tolerate baclofen.

Read more : Klonopin (clonozapam) for spasticity? | Views : 1600 | Replies : 1

Question...IV Solu-Medrol and Spasticity

Hello Everyone,

I am new to the board. Posted an introduction the other day, but have a question for you as I am new to all of this :smile: I was just diagnosed with MS last month, but certain I have had it for much longer.

One of my primary symptoms has always been spasticity. Prior to my diagnosis there were days where I seriously felt as ...
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Botox in ankle

my wife just got her first injection of botox in her ankle.

when doc was done my wife looked at him and said "but doc, my ankle doesn't look any younger" bada bing

when we got home she did a handstand which i questioned, her reply was "the doc said a side affect is the botox can travel to adjoining muscles. i'm hoping gravity brings it to my forehead." bada bang

thanks, i will be ...
Read more : Botox in ankle | Views : 1687 | Replies : 0

bone mineral density & corticosteroids

after being treated with a very high dose of steroids, i was given a diagnosis of schummermans disease & osteo-penia. before the steroids they called it postural hyper-kyphosis.

im a little upset about the situation. how did u guys feel after taking steroids?

The results show that significant reduction in BMD occurs in both groups, however, oral corticosteroids produce significantly more reduction in BMD in the ...
Read more : bone mineral density & corticosteroids | Views : 2070 | Replies : 3

FDA Warning on Tylenol (acetaminophen)

The FDA has recently published a new warning that acetaminophen can cause rare and sometimes lethal skin reactions such as Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) as well as acute generalized exanthematous pustulosis (AGEP). SJS and TEN can cause the skin to separate from the body and slough off.

FDA Warns of Rare Acetaminophen Risk ... 363067.pdf

Other problems with acetaminophen include...
The People's Pharmacy wrote:Long-term use ...
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Tecfidera or thyroid nodule?

Good evening. I am curious...I am losing hair by the handful and have been on tecfidera now 2 weeks. Only side effect is belly ache and when I gotta go...means few minutes from then. My hair is falling out. Endocrinologist appt is two weeks from now and tecfidera doesn't show that side effect. I had a ton of hair...but now I feel.. well soon...will be noticeable. Anyone notice this from tecfidera??
Or you think thyroid ...
Read more : Tecfidera or thyroid nodule? | Views : 2472 | Replies : 2

Azathioprin : imuran

Hi to all out there in interweb land

I have just been diagnosed with autoimmune hepatitis (in addition to relapsing remitting ms) and my liver specialist has advised me that he will soon want to start me on Azathioprin for hepatitis. I understand this is also used as an ms treatment so the question is: anyone out there taking it for ms and does it work?

A little anxious as have got used to fampyra ...
Read more : Azathioprin : imuran | Views : 1899 | Replies : 2

Corticosteroids Boost Risk of Clots

Corticosteroids Boost Risk of Clots ... -of-clots/

    Blood clots deep in the veins are among the leading causes of death in the U.S. They are called deep vein thromboses or DVTs. When a blood clot breaks loose and lands in the lungs it is called a pulmonary embolism and can be a life-threatening event.

    A large new study from Denmark shows that people who start taking oral corticosteroids ...
Read more : Corticosteroids Boost Risk of Clots | Views : 3249 | Replies : 1

Is Pinexel PR better than the antimuscurinics?

Having tried different antimuscurinics with mixed results my uro gave me Pinexel 400mcg once a day to see if it helps

The uro said to take one tablet before bed but the instructions in the box says one in the morning? which is it?

Has anyone used Pinexel prolonged release 400mcg? Were they more effective then the antimuscurinics?
Did it help with how many times you pee per day and accidents? would you recommend
Read more : Is Pinexel PR better than the antimuscurinics? | Views : 2282 | Replies : 0


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