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Gilenya, or Fingolimod, is the first approved oral disease modifying drug for MS.

Third case of PML reported to Novartis

Novartis has been notified of a third case of progressive multifocal leukoencephalopathy (PML) in a patient with relapsing multiple sclerosis (MS) treated with Gilenya... Read More - http://www.ms-uk.org/gilenya
Read more : Third case of PML reported to Novartis | Views : 323 | Replies : 0


FDA issues PML warning for MS patients taking Gilenya

Following reports of progressive multifocal leukoencephalopathy among patients taking Gilenya for multiple sclerosis, the FDA has issued a warning of possible infection for those prescribed the immunosuppressant drug.... Read More - http://www.ms-uk.org/gilenya
Read more : FDA issues PML warning for MS patients taking Gilenya | Views : 386 | Replies : 0


Study finds lesions may compromise heart rate in Gilenya....

Study finds lesions may compromise heart rate in Gilenya patients

In a recent study published in the Journal PLOS One, a team of researchers found that the autonomic cardiovascular dysfunction in MS patients with delayed heart rate re-acceleration upon Gilenya-initiation suggest MS-related central autonomic lesions may compromise heart rate re-acceleration..... Read More - http://www.ms-uk.org/gilenya
Read more : Study finds lesions may compromise heart rate in Gilenya.... | Views : 373 | Replies : 0


Gilenya ‘found to have long-term positive effects’

A new study published in the Journal of Neurology, Neurosurgery and Psychiatry has found long-term Gilenya therapy can maintain a low disease activity in patients with relapsing-remitting multiple sclerosis (RRMS). The study, Long-Term (up to 4.5 years) Treatment With Fingolimod (Gilenya) In Multiple Sclerosis: Results From The Extension Of The Randomised TRANSFORMS Study, was conducted by an international team of researchers..... Read More - http://www.ms-uk.org/gilenya
Read more : Gilenya ‘found to have long-term positive effects’ | Views : 645 | Replies : 0


Researchers suggest short transition period....

Researchers suggest short transition period between RRMS therapies

A team led by researchers at the University Hospital Basel in Switzerland say they have found a short period of eight to 12 weeks is the optimal timing to be considered when patients with relapsing-remitting multiple sclerosis (RRMS) are switched from Tysabri (natalizumab) to Gilenya (fingolimod) therapy.... Read More - http://www.ms-uk.org/gilenya
Read more : Researchers suggest short transition period.... | Views : 545 | Replies : 0


MS mom needs medicine

Dear all,

First of all I want to express my admiration for your courage in facing MS and your kindness in supporting the patients.

My name is Hadeel and I have created this account on behalf of my mother "Hedaya" who has been diagnosed with MS in 2007.
We are Palestinians from Gaza, but my mother lives in the United Arab Emirates (UAE), and I am currently studying in Germany.

In July 2014, my father ...
Read more : MS mom needs medicine | Views : 319 | Replies : 0


New insights into MS treatment

Data from two Novartis phase III clinical trials show that adding brain shrinkage (brain volume loss) to an existing tool to assess multiple sclerosis activity (m-Rio) will give a more precise prediction of the likelihood of future disability progression.... Read More - http://www.ms-uk.org/gilenya
Read more : New insights into MS treatment | Views : 563 | Replies : 0


Gilenya and Airplane travel

Hello all. I am due to start Gilenya at the end of next week. I have been on Copaxone for about 2 years but still seeing a new lesion every few months. Was wondering if anyone has experience traveling on airplanes while on Gilenya. I have to travel internationally every 6-8 weeks (Asia and Latin America) which requires flights of 10-16 hours. I also take a lot of trains so I guess I spend time ...
Read more : Gilenya and Airplane travel | Views : 630 | Replies : 1


Peripheral blood T cell dynamics predict relapse....

Peripheral blood T cell dynamics predict relapse in MS patients on Fingolimod

Fingolimod efficiently reduces multiple sclerosis (MS) relapse by inhibiting lymphocyte egress from lymph nodes through down-modulation of sphingosine 1-phosphate (S1P) receptors. We aimed to clarify the alterations in peripheral blood T cell subsets associated with MS relapse on fingolimod......... Read More - http://www.ms-uk.org/gilenya
Read more : Peripheral blood T cell dynamics predict relapse.... | Views : 414 | Replies : 0


may have to start Gilenya

I registered on this forum largely to find people taking Gilenya and ask about how likely side effects to it are. And WHAT they are most likely to be.
personally I am the side effects queen - to almost all pharmaceuticals. my entire ms history is one with a wide trail of discarded meds I could not tolerate. when I can finally manage to find one that I can tolerate and it works too, I ...
Read more : may have to start Gilenya | Views : 441 | Replies : 0


 

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