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Gilenya, or Fingolimod, is the first approved oral disease modifying drug for MS.

Patient taking Gilenya contracts PML

A woman in a Gilenya after-market study says the company didn’t notify all participants about a new case of progressive multifocal leukoencephalopathy (PML).

Novartis executives have confirmed a multiple sclerosis patient has developed the brain infection after taking their drug Gilenya for more than four years...... Read More - http://www.ms-uk.org/gilenya
Read more : Patient taking Gilenya contracts PML | Views : 281 | Replies : 0


Gilenya may be best in MS patients failing initial treatment

Switching multiple sclerosis patients with disease activity despite treatment with a first-line injectable to oral fingolimod (Gilenya) was associated with fewer relapses than switching them to another standard injectable, researchers have found.

In a study, patients on either interferons or glatiramer acetate (Copaxone) who were switched to fingolimod had a significantly lower mean annualized relapse rate than those who changed to another injectable immunomodulator, according to Tomas Kalincik, MD, PhD, of Royal Melbourne Hospital in ...
Read more : Gilenya may be best in MS patients failing initial treatment | Views : 480 | Replies : 0


MS drug Gilenya may increase risk of lymphopenia

Studies in Sweden and Germany indicate that underweight women with multiple sclerosis who take the MS drug Gilenya (fingolimod) seem to be at increased risk for lymphopenia. The drug also poses a risk for patients who have low lymphocyte levels before they start drug treatment.

Lymphopenia (also known as lymphocytopenia) is a condition in which a person has a deficiency (penia) of lymphocytes, which are a subset of white blood cells (leukocytes). Lymphocytes, which can ...
Read more : MS drug Gilenya may increase risk of lymphopenia | Views : 649 | Replies : 0


Update on fingolimod Phase 3 trial in primary progressive MS

Novartis announced today that the Phase III INFORMS study in primary progressive multiple sclerosis (PPMS) did not show a significant difference between fingolimod and placebo on a combination of disability measures. The safety results were consistent with the well-characterized safety profile of fingolimod in relapsing MS (RMS)....... Read more - http://www.ms-uk.org/gilenya
Read more : Update on fingolimod Phase 3 trial in primary progressive MS | Views : 450 | Replies : 0


Gilenya approved for use in Scotland

SMC first to introduce oral Gilenya® as a first line treatment option for people with a severe form of MS

• Scottish people with a severe form of relapsing remitting multiple sclerosis are first in UK to get access to once daily pill fingolimod as a first line treatment option1
• Once daily pill fingolimod reduces the risk of relapses by 67% compared to placebo

Today, the Scottish Medicines Consortium (SMC) has accepted once daily ...
Read more : Gilenya approved for use in Scotland | Views : 760 | Replies : 0


Gilenya in new therapeutic indication: Added benefit not...

Gilenya in new therapeutic indication: Added benefit not proven

The immunosuppressive drug fingolimod (trade name: Gilenya) was approved for an expanded therapeutic indication in May 2014: It is now also available for adults with highly active relapsing remitting multiple sclerosis (RRMS) who had received other pretreatment than interferon beta (IFN-β). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and ...
Read more : Gilenya in new therapeutic indication: Added benefit not... | Views : 842 | Replies : 0


Gilenya Side Effects?

I have been taking Gilenya since March 2013 and after 9 years on Betaferon it's been brilliant. However this year it seems like the side effects have started to kick in. Around Easter 2014 I started experiencing low back pain, but only when I am lying down to sleep. Some nights are ok, but other nights it's really painful. When it is bad I find it very difficult to turn over and even if I ...
Read more : Gilenya Side Effects? | Views : 1023 | Replies : 0


Wider use of MS drug Gilenya approved in Europ

The European Commission has endorsed the recent Committee for Medicinal Products for Human Use (CHMP) positive opinion recommending the expanded use of Swiss drug major Novartis’ drug Gilenya (fingolimod) for adult patients with highly active relapsing-remitting multiple sclerosis (RRMS)..... Read More - http://www.ms-uk.org/gilenya
Read more : Wider use of MS drug Gilenya approved in Europ | Views : 2159 | Replies : 0


Three months on Gilenya

Well I have been on a Gilenya for 3 months.
No flares or anything. Easiest med I have been on for MS.
My neuro wants 1st blood work between 3 & 4 months.
How often is blood work typically done?
Read more : Three months on Gilenya | Views : 2065 | Replies : 4


Gilenya appears to slow brain volume loss in relapsing patie

Novartis International AG ( NVS ) announced new data showing that more patients with relapsing multiple sclerosis treated with Gilenya (fingolimod) achieved an average annual rate of brain volume loss within the range of those expected for healthy adults of a similar age vs. those patients taking placebo. People with multiple sclerosis experience shrinkage of the brain up to three to five times faster. This acceleration starts early in people with relapsing MS, even before ...
Read more : Gilenya appears to slow brain volume loss in relapsing patie | Views : 1067 | Replies : 0


 

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