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Gilenya, or Fingolimod, is the first approved oral disease modifying drug for MS.

Real risk of ‘rebound syndrome’ after stopping Gilenya...

Real risk of ‘rebound syndrome’ after stopping Gilenya treatment, study claims

‘Rebound syndrome’ following cessation of Gilenya for multiple sclerosis occurs at a clinically relevant rate, shows research, prompting the need for further study on how best to sequence and discontinue such drugs...Read more - http://www.ms-uk.org/MSnews
Read more : Real risk of ‘rebound syndrome’ after stopping Gilenya... | Views : 312 | Replies : 0


Interim report into Gilenya safety released

Once-daily Gilenya therapy is effective after four years of real-world clinical use among patients with relapsing remitting multiple sclerosis (RRMS), and has a safety profile that is “broadly consistent” with that identified in clinical trials, according to an interim analysis from the PANGAEA long-term safety, tolerability, and effectiveness non-interventional study, presented at the 68th annual American Academy of Neurology meeting...Read more - http://www.ms-uk.org/MSnews
Read more : Interim report into Gilenya safety released | Views : 338 | Replies : 0


Gilenya shown to benefit neurons

The immune system-suppressing multiple sclerosis (MS) drug Gilenya also has potentially beneficial effects on the nervous system, according to a recent study...Read more - http://www.ms-uk.org/MSnews
Read more : Gilenya shown to benefit neurons | Views : 347 | Replies : 0


Anyone carry the JC virus and take Gilenya?

Hi all! I've been taking Aubaggio for the last few years, but my neurologist wants me to switch meds as I've had two relapses in the last two years. He is suggesting Gilenya - but I've just been reading about the PML cases, and I've been tested for the JC Virus in the past and my result was positive. Is anyone else in the same boat? Did you decide to take the risk, or did ...
Read more : Anyone carry the JC virus and take Gilenya? | Views : 477 | Replies : 0


ponesimod (or gillenia) effects

I have been proposed to try to take part in ponesimod clinical trial, third phase (without placebo). Ponesimod is a drug made by Actellion, the Swiss pharmaceutical company. That is a drug close to gilenia and RPC1063. they all three sequester lymphocytes into lymph nodes.

Does it worth it? Is gilenia really effective drug? What is the estimated rate of disability slowing? What side effects have to be aware of?
Read more : ponesimod (or gillenia) effects | Views : 851 | Replies : 1


Patients treated with Gilenya “show benefits”

New research evaluating Gilenya’s clinical efficacy, safety, and tolerability in patients with relapsing-remitting multiple sclerosis (RRMS) has largely supported its use, finding the oral drug’s efficacy in a real-world setting was comparable to results observed in Phase 3 clinical studies...Read more - http://www.ms-uk.org/MSnews
Read more : Patients treated with Gilenya “show benefits” | Views : 677 | Replies : 1


Generic Gilenya rival launched in Russia

Russian firm BioIntegrator says it has successfully launched Neskler -- the first generic version of Gilenya...Read more - http://www.ms-uk.org/MSnews
Read more : Generic Gilenya rival launched in Russia | Views : 607 | Replies : 1


Gilenya ‘prevents activation of key immune cells’

In a recent study entitled Myeloid Cells As Target Of Gilenya Action In Multiple Sclerosis, a team of scientists investigated the impact of MS treatment Gilenya on the reactivity of myeloid cells, a key group that comprises several immune cells that are activated in MS patients and the underlying cause of the condition. The study was published in the journal Neurology...Read more - http://www.ms-uk.org/MSnews
Read more : Gilenya ‘prevents activation of key immune cells’ | Views : 865 | Replies : 0


No conclusions over best drug for Multiple Sclerosis

Two studies - one from France, the other from Denmark - came to conflicting conclusions about whether Tysabri or Gilenya offers better efficacy, researchers have reported here... Read More - http://www.ms-uk.org/MSnews
Read more : No conclusions over best drug for Multiple Sclerosis | Views : 935 | Replies : 0


Long-term efficacy of Gilenya reinforced by new analysis

Novartis has announced a new analysis from the phase III FREEDOMS and FREEDOMS II trials reinforcing the long-term efficacy profile of Gilenya. The analysis evaluated the proportion of Gilenya patients with relapsing-remitting multiple sclerosis (RRMS) achieving 'no evidence of disease activity' (NEDA-4) every year over seven years... Read More - http://www.ms-uk.org/MSnews
Read more : Long-term efficacy of Gilenya reinforced by new analysis | Views : 759 | Replies : 0


 

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