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When break dancers play soccer...


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Read more : When break dancers play soccer... | Views : 257 | Replies : 0 | Forum : Humor


Vasovagal reaction to bloodwork prior to spinal tap

I went and got my lumbar puncture Tuesday afternoon, and it went pretty well. I only felt the initial needle prick and after that it was completely painless. The doctor used flouroscopy to guide the needle and I laid on my stomach during the entire thing, which took about half an hour. I made sure to drink a lot of water afterwards (and some tea, for the caffeine), so I didn't develop a bad headache ...
Read more : Vasovagal reaction to bloodwork prior to spinal tap | Views : 258 | Replies : 0 | Forum : General Discussion


accelerated cure launches distributed research

iConquerMS™ Initiative Launches Personalized Medicine Research in Multiple Sclerosis

REAL MS™ Will Explore Causes and Factors that Affect Progression and Treatment Outcomes

https://www.prnewswire.com/news-release ... 25718.html

WALTHAM, Mass., Sept. 12, 2016 /PRNewswire-USNewswire/ -- iConquerMS™ (www.iConquerMS.org), a research initiative of the Accelerated Cure Project for Multiple Sclerosis, today launches REAL MS™, a prospective longitudinal study of multiple sclerosis intended to answer important questions about the ...
Read more : accelerated cure launches distributed research | Views : 307 | Replies : 0 | Forum : General Discussion


Personalised medicine in MS: A step forward.

Personalised medicine tries to select the best medicine available for each patient based in biomarkers. Now this is starting to be possible in MS.

In the world of MS where each medicine works for some patients and not others this is really important. Specially having collateral effects into account.

An Important but Limited Step Forward in Personalized Multiple Sclerosis Care
Dr. Robert Fox puts a tissue marker study in context

https://consultqd.clevelandclinic.org/a ...


Personalized medicine in multiple sclerosis

Personalized medicine here means to divide the patients in subgroups so that the response to medication is optimal.

It seems that some hospitals are already doing a personalized diagnosis (for example https://www.hopkinsmedicine.org/inhealt ... rosis.html , https://hitconsultant.net/2016/10/18/jo ... e-centers/). Given the amount of compounds for MS that we have, that all of them have secondary effects and that not all of them work for ...
Read more : Personalized medicine in multiple sclerosis | Views : 250 | Replies : 0 | Forum : MS Etiology and Pathogenesis


Progressive MS: Natural evolution in PPMS and SPMS

Pathology and Pathogenesis of Progressive Multiple Sclerosis: Concepts and Controversies

https://pdfs.semanticscholar.org/e4a3/a ... 1d33fa.pdf

Summary

Multiple sclerosis changes not only its clinical appearance, but also
its pathological and pathomechanistic characteristics when transitioning
from the relapsing-remitting phase into the progressive
phase.

While focal lesions of the white matter are predominant in
the RR phase, diffuse changes of gray and white matter determine
the pathology of progressive MS. In this stage, the ...
Read more : Progressive MS: Natural evolution in PPMS and SPMS | Views : 251 | Replies : 0 | Forum : MS Etiology and Pathogenesis


Heterogeneity: CSF profile predicts response to interferons

In a small study patients were clustered into 6 distinct subsets by baseline cytokine profiles of CSF.

Two subsets were associated with patients who responded poorly to therapy. Two other subsets showed a significant reduction in relapse rates and no worsening of disability.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747480/

Results:

A total of 157 patients were included in the study and clustered into 6 distinct subsets by baseline cytokine profiles. These subsets differed significantly ...


DR.SU METALFE'S COMPANY COULD BE ON THE VERGE OF CURING M.S

Dear friends please read
http://ushealthmagz.com/2018/07/03/meet ... sclerosis/
Dr.Sumetalfe's company LiFNano could be on the verge of curing M.S
Regards
Seeva
Read more : DR.SU METALFE'S COMPANY COULD BE ON THE VERGE OF CURING M.S | Views : 459 | Replies : 2 | Forum : Drug Pipeline


2018 review: MS Patients' Use of Vitamins & Supplements

can't get into full text for this one, so no opportunity to critique as yet:

Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis
https://jamanetwork.com/journals/jamane ... ct/2679039

Abstract
Importance Surveys of patients with multiple sclerosis report that most are interested in modifying their diet and using supplements to potentially reduce the severity and symptoms of the disease. This review provides an updated overview of the current state ...
Read more : 2018 review: MS Patients' Use of Vitamins & Supplements | Views : 240 | Replies : 1 | Forum : Natural Approach


Barts blog: EBV in Brain

EBV in Brain

Source: http://multiple-sclerosis-research.blog ... brain.html

The best evidence to date does suggest that EBV is present in both MS and control brains, but is more common in pwMS (90% vs 24%).
Clearly, the presence of EBV-infected B cells in the brain is not sufficient to drive disease activity. Further work needs to be done to understand why some people are perfectly healthy despite having EBV in their ...
Read more : Barts blog: EBV in Brain | Views : 241 | Replies : 0 | Forum : MS Etiology and Pathogenesis


 

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