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HERVs reactivation linked to demyelination

HERVs (human endogenous retroviruses) are linked to the initiating microglial inflammation

Up-to-date knowledge about the association between multiple sclerosis and the reactivation of human endogenous retrovirus infections

https://link.springer.com/article/10.10 ... 018-8783-1

Summary: Overwhelming pieces of evidence confirm that the reactivations often drive the demyelinating plaques by initiating microglial inflammation
Read more : HERVs reactivation linked to demyelination | Views : 146 | Replies : 0 | Forum : MS Etiology and Pathogenesis


Desperate

My Name is Russ and I was diagnosed in 2000. the progression has increased noticeably in the past 6 months.

I would rather stay in then go out and cooking and cleaning is difficult.

Not sure why am here....
Read more : Desperate | Views : 268 | Replies : 1 | Forum : Introductions


Higher dose of MS drug Glatopa finally gets US approval

Sandoz, a Novartis division, has announced US Food and Drug Administration (FDA) approval and launched a 40 mg/ml dose of Glatopa, a glatiramer acetate injection…Read more - http://www.ms-uk.org/higher-dose-ms-drug-glatopa-finally-gets-us-approval

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Read more : Higher dose of MS drug Glatopa finally gets US approval | Views : 246 | Replies : 0 | Forum : General Discussion


Cladribine gets approval in Scotland

NHS Scotland has accepted cladribine (Mavenclad) as a treatment option for people with highly active multiple sclerosis (MS) living in Scotland… http://www.ms-uk.org/cladribine-gets-approval-scotland

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Read more : Cladribine gets approval in Scotland | Views : 216 | Replies : 0 | Forum : General Discussion


Experimental therapy restores nerve insulation damage

Experimental therapy restores nerve insulation damage caused by autoimmune conditions

When the body attacks its own healthy tissues in an autoimmune condition, peripheral nerve damage disable people and causes persistent neuropathic pain when insulation on healing nerves doesn't fully regenerate…Read more - http://www.ms-uk.org/experimental-therapy-restores-nerve-insulation-damage-caused-autoimmune-conditions

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Read more : Experimental therapy restores nerve insulation damage | Views : 247 | Replies : 0 | Forum : General Discussion


Question about PPMS diagnosis and disease course

Hi there. My husband was diagnosed with RRMS last May but now the doctor thinks he has PPMS. My husband is 44. I realize that MS is unpredictable and that everyone's MS is different (I was diagnosed with RRMS in July and we have completely different symptoms), but does anyone know how fast his MS might progress? We are looking at houses right now and were going to just buy something we like, but what ...
Read more : Question about PPMS diagnosis and disease course | Views : 462 | Replies : 21 | Forum : General Discussion


Ocrevus

Hi there. My husband was diagnosed with RRMS back in May, but now the doctor thinks he may have PPMS. He suggested that we look into Ocrevus. I have been reading about it a little and it sounds scary (could cause cancer, could lead to death), but it's the only MS drug out there that treats PPMS. Anyone have any experience with it?
Read more : Ocrevus | Views : 274 | Replies : 1 | Forum : Regimens


New 5-mer peptide teats inflammatory disease models

One drug could treat Alzheimer’s, MS, Crohn’s and more

https://www.israel21c.org/one-drug-coul ... -and-more/

"Could one drug effectively treat incurable inflammatory diseases such as Crohn’s disease, ulcerative colitis, rheumatoid arthritis and multiple sclerosis as well as neurodegenerative maladies such as Alzheimer’s disease?"
Read more : New 5-mer peptide teats inflammatory disease models | Views : 212 | Replies : 0 | Forum : General Discussion


The Engineers approach

Don't grouse, degauss. If you can't chill out, chelate!


Most of what I want to say, is in direct response to published statistics.

We know that there is no MS at the equator, but it increases both in frequency and severity towards the poles. The question why, remains.


Here, I need you to do something. This is pivotal, but extremely simple.

Cut from thin card, two pieces measuring 160mm X 40mm. An old cereal box ...
Read more : The Engineers approach | Views : 281 | Replies : 1 | Forum : General Discussion


Patterns: Different symptoms. Apheresis.

Forgetting around 1% of MS people with a pattern IV, all the cases belong to a given pattern. Apheresis (lack of proper spelling for some words) could make the difference.

Differences in the Reponses to Apheresis Therapy of Patients With 3 Histopathologically Classified Immunopathological Patterns of Multiple Sclerosis


https://jamanetwork.com/journals/jamane ... irect=true

Question Are there any differences in the response to apheresis therapy for steroid refractory relapses among ...
Read more : Patterns: Different symptoms. Apheresis. | Views : 237 | Replies : 0 | Forum : MS Etiology and Pathogenesis


 

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