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Increased MS relapse rates after Tysabri discontinuation

Treatment of Relapsing-Remitting Multiple Sclerosis After 24 Doses of Natalizumab -<br>
Evidence From an Italian Spontaneous, Prospective, and Observational Study (the TY-STOP Study)

Marinella Clerico, MD; Irene Schiavetti, BS; Stefania F. De Mercanti, MD; Federico Piazza, MD; Dario Gned, MD; Vincenzo Brescia Morra, MD; Roberta Lanzillo, MD; Angelo Ghezzi, MD; Anna Bianchi, BS; Giuseppe Salemi, MD; Sabrina Realmuto, MD; Patrizia Sola, MD; Francesca Vitetta, MD; Paola Cavalla, MD; Damiano Paolicelli, MD; Maria Trojano, MD; Maria ...

'Master switch' for myelination in human brain stem cells...

'Master switch' for myelination in human brain stem cells is identified

Scientists at the University at Buffalo have identified the single transcription factor or "master switch" that initiates the critical myelination process in the brain. The research will be published online in Proceedings of the National Academy of Sciences (PNAS) on June 30.

The identification of this factor, SOX10, in human brain cells, brings researchers closer to the goal of treating multiple sclerosis (MS) by ...
Read more : 'Master switch' for myelination in human brain stem cells... | Views : 487 | Replies : 0 | Forum : Stem Cells

First Exoskeleton Gets FDA Approval For U.S. Sales

Finally starting to see the first of the robotic devices for paralyses as hopefully in the near future these will be designed for those of us with neurological diseases and not just for spinal cord paralyses. ... a-approval
Read more : First Exoskeleton Gets FDA Approval For U.S. Sales | Views : 711 | Replies : 1 | Forum : Medical Devices


hello everyone! :-D
Read more : *waves* | Views : 414 | Replies : 2 | Forum : Introductions

Melatonin Acts as Antioxidant and Improves Sleep

Pubmed article about melatonin and MS:

I used to use medicinal marijuana to help with sleep problems, but gave this up because of cost and quality issues. I've been using melatonin for several months now, and sleep very soundly. I use a low dose capsule, 300 mcg daily, in a timed release formula that is available on amazon.

Interesting that at this low daily dose (300 millionths of ...
Read more : Melatonin Acts as Antioxidant and Improves Sleep | Views : 440 | Replies : 2 | Forum : General Discussion

Caregiver for 12+ years

My name is Laura. I've been a caregiver for my husband James for over 12 years. His first onset was November 2001 - ON. We had a 4 1/2 month old son, his first newborn (and only), my fourth. It took 15 months for an official DX. The last 3 years MS has taken its toll physically. As we wait and hope for SSDI, we're trying not to be evicted and pay the bills. At ...
Read more : Caregiver for 12+ years | Views : 266 | Replies : 1 | Forum : Introductions

Spinal cord loss associated with disability in MS

Cervical spinal cord volume loss is related to clinical disability progression in multiple sclerosis.

Lukas C, Knol DL, Sombekke MH, Bellenberg B, Hahn HK, Popescu V, Weier K, Radue EW, Gass A, Kappos L, Naegelin Y, Uitdehaag BM, Geurts JJ, Barkhof F, Vrenken H.


OBJECTIVE: To examine the temporal evolution of spinal cord (SC) atrophy in multiple sclerosis (MS), and its association with clinical progression in a large MS cohort.... Read More -
Read more : Spinal cord loss associated with disability in MS | Views : 386 | Replies : 0 | Forum : General Discussion

end of life issues

I see, being new to this forum and having vaguely browsed through the forum categories, that there is no mention of the end of life issues.

My husband is presently paralyzed (except for his left arm and hand), living in a nursing home, and is starting to have hallucinations and delusions brought by the MS.

So I was hoping to find some tips about how to deal with this on this thread ("Mental and Spiritual ...
Read more : end of life issues | Views : 650 | Replies : 3 | Forum : Mental & Spiritual Health

33 year old male with RRMS

Hello everyone!!

My name is Bryan and I live in Alaska. I figured I would share my story with people and also talk to others with MS so i have people that would understand and also share what I go through. Every day I experience pain, headaches, dizziness, you name it. Have fell down a flight of stairs last year because of weekness and dizziness. But I'm trucking along...

I apologize ahead of time for ...
Read more : 33 year old male with RRMS | Views : 416 | Replies : 4 | Forum : Introductions

Confused of MS diagnosis


Reading MS report and confused about the conclusion:

"At least 7 focal white matter lesions are scattered throughout the blah blah..fulfilling McDonald criteria for MS....
However there is no contrast enhancement of these lesions to confirm a newly developed lesion or previous imaging available for comparison to confirm dissemination in time. Clinical review and ongoing imaging follow up therefore is recommended to further confirm the suspected diagnosis of MS"

Now does this mean docs ...
Read more : Confused of MS diagnosis | Views : 379 | Replies : 1 | Forum : Introductions


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