In researching why some people respond to steroids, and others do not, I've come across research by Drs. Lucchinetti/Lassmann/Bruck on the Subtypes of Multiple Sclerosis Lesions. These doctors have studied MS lesions for many years, in vivo and on autopsy, and have catagorized lesions into four distinct patterns:
-Centered around venule with sharp, demarcated edges
-oliogodendrocytes in lesion center
-Antibody/complement associated, lesions contain large quantities of immunoglobulin ...