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natalizumab and reducing vision loss

MS drug helps reduce vision loss 16 April 2007

A drug that slows disability and reduces relapse rates in multiple sclerosis (MS) has been found to also reduce vision loss in patients with relapsing MS. Vision loss is one of the most common and debilitating symptoms of MS. The findings are published in the April 17, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology.

The analyses were performed on data ...
Read more : natalizumab and reducing vision loss | Views : 976 | Replies : 0 | Forum : Drug Pipeline


Ever had a day like this??

Please tell me I'm not crazy--or at least not alone :lol:

I woke up this morning and my right calf hurt like I had a pulled muscle. I have been working out regularly and figured that I just overdid it yesterday. But in the back of my mind I was probably wondering if it was the start of a relapse since my right leg is always affected. ...
Read more : Ever had a day like this?? | Views : 2847 | Replies : 19 | Forum : General Discussion


Is this "normal" for MS?

I was diagnosed in the summer of 2005 after ending up in the ER unable to speak although I was seeking answers to my symptoms since 2002. Since the attack in 2005, I have regained most of my speech (still slur some words) but have other issues such as right-sided numbness and muscle stiffness including a slight facial drop, some difficulty with my handwriting and issues with my right foot that cause minor gait problems. ...
Read more : Is this "normal" for MS? | Views : 1984 | Replies : 10 | Forum : General Discussion


Veterans and MS

New Research To Examine Increased Risk of Multiple Sclerosis Among US Veterans 15 April 2007

Cases Suggest MS Could be Driven by Environmental Factors.
Emerging research has identified a possible increased risk of developing multiple sclerosis (MS) among Gulf War veterans. Data from the Department of Veterans Affairs MS Centres of Excellence and the Department of the Defense will help further investigate the link.

Of veterans with MS who were deployed in the Gulf War, ...
Read more : Veterans and MS | Views : 13072 | Replies : 46 | Forum : Veterans and MS


ranting about a doctor or two

okay i'm really mad. this is not about ms it's about a lady in her 80s. below is the summary of her medical care over the last few years. but it all started with her asking me to look at her bloodwork results the other day. she had her CBC results and her MPV, MCH, MCV, and her RDW were all high. now, the history.

- receiving b12 shots from doctor #1
- doctor #1 ...
Read more : ranting about a doctor or two | Views : 1581 | Replies : 0 | Forum : Daily Life


Varicella Zoster

1: J Neurol. 2007 Mar 31; Links
Varicella-zoster virus at relapses of multiple sclerosis.Sotelo J, Ordonez G, Pineda B.
Neuroimmunology Unit, National Institute of Neurology and Neurosurgery of Mexico, Insurgentes Sur 3877, 14269, Mexico City, Mexico, jsotelo@servidor.unam.mx.

The possible participation of different herpes viruses was studied during exacerbations of multiple sclerosis (MS). We searched for the presence of DNA from the following herpes viruses: varicella zoster ...
Read more : Varicella Zoster | Views : 873 | Replies : 0 | Forum : General Discussion


Nicotinamide etc.

This abstract provides a rationale for the use of, among other things, niacin and nicotinamide:

Pharmacological Targeting of IDO-Mediated Tolerance for Treating Autoimmune Disease.

Penberthy WT.

University of Cincinnati, Building C Room 217A, 2180 E. Galbraith Road, Cincinnati, OH 45237, USA. WTPENBER@YAHOO.COM.

Immunomodulatory factors including IFNgamma, TNFalpha, IL-1, and LPS use IDO induction in responsive antigen presenting cells (APCs) also to transmit tolerogenic signals to T cells. Thus it makes ...
Read more : Nicotinamide etc. | Views : 861 | Replies : 0 | Forum : General Discussion


More Aggressive Forms

Along the way I've noticed that the Japanese are affected with a more aggressive form of MS as it is also speculated that African Americans, the male sex and indeed it seems that in the US, as MS strikes an increasing percentage of the population, it's been speculated that it was more aggressive when it first began it's increasing incidence which is sometimes considered to have really started rolling in the 1950's.

Of course this ...
Read more : More Aggressive Forms | Views : 1186 | Replies : 6 | Forum : General Discussion


Question about CRAB's...

Has anyone heard of Copaxone being favored/effective only for milder cases of RRMS (i.e. situations where there is almost complete recovery and little residual symptoms), and interferon’s being favored in cases where there are more residual symptoms present with RRMS.

Or is Copaxone being used regardless of the severity of the RRMS?

Any advice/information is greatly appreciated. Thanks!
Read more : Question about CRAB's... | Views : 1458 | Replies : 4 | Forum : General Discussion


Vitamin D study in Tasmania

This study appears to strongly reinforce the notion that vitamin D levels are closely associated with the amount of disability in MS:


1: J Neurol. 2007 Apr 11; Links
Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia.van der Mei IA, Ponsonby AL, Dwyer T, Blizzard L, Taylor BV, Kilpatrick T, Butzkueven H, McMichael AJ.
Menzies Research Institute, Private Bag 23, Hobart, Tasmania, 7001, Australia, ...
Read more : Vitamin D study in Tasmania | Views : 895 | Replies : 1 | Forum : General Discussion


 

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