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Familial influences and MS.

Here is a link to an article I found on, "MedPage Today",

http://www.medpagetoday.com/Neurology/M ... is/tb/4953

To be honest, I think they could have saved themselves the trouble and just written, "MS is quite complicated".

Ah well. I suppose even the most fruitless research is worth doing, because the answers we need might turn up in the most unexpected places,

Dom.
Read more : Familial influences and MS. | Views : 928 | Replies : 0 | Forum : General Discussion


Estriol trial

Some news on a phase II trial of estriol in the US. I'm adding it to the pipeline, don't know why I hadn't done that already...



New Trial for MS Drug

January 29, 2007 - The Press-Enterprise - People living with multiple sclerosis have to use injections to help control the disease. The method is the only anti-inflammatory treatment available.

But a new clinical trial, which is seeking participants, may help women with MS get ...
Read more : Estriol trial | Views : 1650 | Replies : 3 | Forum : Drug Pipeline


More evidence on Cannabis for pain

Hopefully regulators around the world get their thumbs out and start approving cannabis in whatever form for MS-related pain.



Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain.

Curr Med Res Opin. 2007 Jan;23(1):17-24.
Iskedjian M, Bereza B, Gordon A, Piwko C, Einarson TR.
PharmIdeas Research & Consulting Inc., Oakville, ON, Canada; PharmIdeas USA Inc., Charlotte, NC, USA.

OBJECTIVE: Debilitating pain, occurring in 50-70% of multiple sclerosis (MS) patients, is poorly understood and ...
Read more : More evidence on Cannabis for pain | Views : 1970 | Replies : 12 | Forum : General Discussion


Trial progress update

They seem to be enrolling people quickly...



Opexa Achieves Midpoint in Patient Admissions in Phase IIb Trial of Tovaxin for Multiple Sclerosis

Jan 30/2007 - BUSINESS WIRE - Opexa Therapeutics announced today that it has admitted the first 75 patients in its 150-patient Phase IIb clinical trial of Tovaxin in multiple sclerosis. Enrollment is expected to be completed by mid-2007. There are currently 34 trial sites in the U.S., all of which are actively recruiting ...
Read more : Trial progress update | Views : 1589 | Replies : 1 | Forum : Tcelna (Tovaxin)


Peace Like a River - Leif Enger

I can tell after only 100 or so pages that this is one of those books that's going to make me want to be a better person. Has anyone else read this book?
Read more : Peace Like a River - Leif Enger | Views : 3244 | Replies : 2 | Forum : Reading Nook


Cochrane review of cyclophosphamide

I guess this validates cytoxan not being approved as an MS therapy.



Cyclophosphamide for multiple sclerosis.

Cochrane Database Syst Rev. 2007 Jan 24;(1):CD002819.
La Mantia L, Milanese C, Mascoli N, D'Amico R, Weinstock-Guttman B.

BACKGROUND: Multiple sclerosis is a presumed cell-mediated autoimmune disease of the central nervous system. Cyclophosphamide (CFX) is a cytotoxic and immunosuppressive agent, used in systemic autoimmune diseases. Controversial results have been reported on its efficacy in MS. We conducted a systematic ...
Read more : Cochrane review of cyclophosphamide | Views : 1446 | Replies : 3 | Forum : Drug Pipeline


B cells

Edmond scientist discovers hidden antibodies in mice

A discovery by an Oklahoma Medical Research scientist has discredited the 50-year-old accepted dogma that disease fighting cells in the body carry only one protein.

Edmond’s Patrick Wilson has discovered that B cells can make a mistake when the cells bind to human tissue and change receptors. Cells changing receptors sometimes may result in a second allele (chromosome) producing a second antibody protein, he found. Wilson revealed ...
Read more : B cells | Views : 860 | Replies : 1 | Forum : General Discussion


One problem with the "golden years"...

One problem with the so-called golden years is that just as you are starting to need more help yourself, the family who might have been there to help when you were younger are now needing help themselves--and dying off.

So you find yourself becoming more and more isolated. You can't replace your family. You'll never have another, probably. When they're gone, they're gone.

All of my siblings were old enough to have been another generation. ...
Read more : One problem with the "golden years"... | Views : 3875 | Replies : 7 | Forum : MS in the Golden Years


Pen Again Ergonomic Pen

Pen Again ergonomic pen.
I had one of these new pen bought for me, as using normal, thin biro's and pens aint so easy for me anymore. The pen is great, comfortable to write with and easy to write with despite my numb, pins and needles fingers.
The is a (U.S) website:

www.penagain.com

A google search will show you where you can get them locally (I am in Melbourne, ...
Read more : Pen Again Ergonomic Pen | Views : 2939 | Replies : 0 | Forum : Shopping


Immune System Brakes

Immune system 'brakes' found

Scientists say they have learnt how the body controls the machinery it uses to fight infections and foreign invaders.

The advance, published in the journal Nature, may one day help find ways to tackle unwanted immune reactions following transplant surgery.

The Johns Hopkins University researchers say a protein molecule called carabin may be the body's way of restraining its defences.

The US-based team describes it as a 'built-in timer' for ...
Read more : Immune System Brakes | Views : 1022 | Replies : 2 | Forum : General Discussion


 

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