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Mitoxantrone + Copaxone

I think this combo is in trials. It is an approach being examined at a neurological clinic in Liverpool, England.

COPAXONE(R) Treatment over Two Years after Short Term Induction with Mitoxantrone Provided Sustained Benefits to Active Relapsing-Remitting Multiple Sclerosis Patients 04 May 2007

Increased Efficacy on MRI and Clinical Outcomes Achieved at 15 Months Was Sustained for 24 Months in Follow-up Study.

New data have demonstrated that relapsing-remitting multiple sclerosis (RRMS) patients treated with ...
Read more : Mitoxantrone + Copaxone | Views : 1093 | Replies : 0 | Forum : Drug Pipeline

Hi I'm new from the UK

Hi there everyone,

I am new here. I was directed to this website from MSRC for realistic views on DMD's. I was dx in Feb 2007 after quite a bad relapse. As others have said many websites sit on the fence with some of the information they give, and as MS is a life changing event, it is helpful to see the good and the bad in the disease from fellow MSer's with millions of ...
Read more : Hi I'm new from the UK | Views : 1409 | Replies : 2 | Forum : Introductions

Drug info

For those of you who like to know about the meds you are taking (especially off label), the following web site contains a wealth of info, and has a free trial period.
Read more : Drug info | Views : 983 | Replies : 0 | Forum : General Discussion

Natalizumab in multiple sclerosis: unclear patient benefits

* Schipper JP.

Ziekenhuis Bethesda, afd. Neurologie, Dr.G.H.Amshoffweg i, 7909 AA Hoogeveen.

Two large randomised clinical trials were published in March 2006 that evaluated the effect of natalizumab on the incidence of disease exacerbation in patients with multiple sclerosis (MS). Both trials showed that natalizumab reduces the incidence of MS exacerbations, but it is unclear whether patients ultimately benefited ...
Read more : Natalizumab in multiple sclerosis: unclear patient benefits | Views : 1092 | Replies : 0 | Forum : General Discussion

Still no evidence on the efficacy of immunomodulatory therap

Still no evidence on the efficacy of immunomodulatory therapy in reducing functional impairment in multiple sclerosis

* Vermeulen M.

Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Neurologie, Postbus 22.660, II00 DD Amsterdam..

Immunomodulatory therapy reduces the rate of relapse in multiple sclerosis (MS) by 30% in the first year of treatment; the effect in the second year is uncertain. Relapse is caused by the effects of inflammation ...
Read more : Still no evidence on the efficacy of immunomodulatory therap | Views : 1080 | Replies : 0 | Forum : General Discussion

MBP8298 trial for RRMS

Another hurdle jumped for MBP8298

BioMS Medical completes patient recruitment in MINDSET-01 phase II relapsing-remitting multiple sclerosis trial

May 3 - CNW - BioMS Medical today announced that it has completed patient recruitment in its phase II clinical trial of MBP8298 for the treatment of relapsing-remitting MS (RRMS). The trial, named MINDSET-01, includes approximately 215 patients, and is being conducted at 24 trial sites in six countries across Europe.

"Reaching full recruitment in our relapsing-remitting ...
Read more : MBP8298 trial for RRMS | Views : 1187 | Replies : 0 | Forum : Drug Pipeline

Tysabri info presented at AAN

Data Presented at the American Academy of Neurology's Annual Meeting Provide Update on Utilisation and Safety of TYSABRI(R) in Patients with Multiple Sclerosis 03 May 2007

Additional Data From Extension Study Presented Show TYSABRI Benefit is Sustained Over Three Years.

Biogen Idec and Elan Corporation, plc announced today that new data from the TOUCH Prescribing Program(TM) and TYGRIS safety study confirm the safety profile from previous clinical studies of TYSABRI(R) (natalizumab). Also presented at ...
Read more : Tysabri info presented at AAN | Views : 1728 | Replies : 0 | Forum : Tysabri (Antegren or Natalizumab)

Fampridine results

Acorda Therapeutics Presents Data from its Phase 3 Study of Fampridine-SR in Multiple Sclerosis at the American Academy of Neurology Meeting

03 May 2007

Acorda Therapeutics, Inc.® today presented data from a Phase 3 clinical trial of Fampridine-SR in people with multiple sclerosis (MS) at the American Academy of Neurology meeting. Andrew Goodman, M.D., Director of the Multiple Sclerosis Center at the University of Rochester, presented top-line results on walking ability, leg strength, spasticity ...
Read more : Fampridine results | Views : 1408 | Replies : 0 | Forum : Drug Pipeline

MS simulator machine

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Just maybe of interest to some...
Read more : MS simulator machine | Views : 1369 | Replies : 3 | Forum : General Discussion

Th1 and Th2 responses: what are they?

This paper makes a few oft heard terms a little more understandable. I'm not certain of the exact date but I THINK it's from August 12, 2000.

Th1 and Th2 responses: what are they?

Abi Berger, science editor.


Cytokines are the hormonal messengers responsible for most of the biological effects in the immune system, such as cell mediated immunity and allergic type responses. Although they are numerous, cytokines can be functionally divided into ...
Read more : Th1 and Th2 responses: what are they? | Views : 3171 | Replies : 15 | Forum : General Discussion


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