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Discontinuing Tysabri due to worsening

It's great that everybody is having such good results with Ty, but I have just decided to STOP after 5 infusions, because of continued worsening of symptoms. No improvements at all... not even a tiny bit! Now, I should consider myself "lucky", since I only have leg weakness and inability to walk unaided. NO other symptoms, except poor circulation in feet due to lack of walking. I have been on a steady decline over the ...
Read more : Discontinuing Tysabri due to worsening | Views : 2510 | Replies : 2 | Forum : Tysabri (Antegren or Natalizumab)


negative oligoclonal bands

hi folks,

when i went through my diagnostics with my neuros (there was more then one), my CSF was negative for the oligoclonal bands...i have since read articles stating that around 10-15% of people positive for MS have this result with their CSF studies...i don't know if this is an old topic or not, but i was just wondering if anyone else also had a negative CSF...and, if so, if anyone has any info on ...
Read more : negative oligoclonal bands | Views : 3176 | Replies : 21 | Forum : General Discussion


rHIgM22 immunglobuline to build new myelin

I wanted to share that interesting article i just came across:

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Greets

--Frank
Read more : rHIgM22 immunglobuline to build new myelin | Views : 7346 | Replies : 21 | Forum : General Discussion






Clotting disorders and MS

Hi
I have been sent for tests to find out why I keep having miscarriages. I know Hughes syndrome is a nice outcome to get if you've MS, but sadly I have tested negative for Hughes, and thankfully, negative for Lupus.
But I have been told today I have another clotting disorder, but I'll find out which one on tues (dontcha love the medical profession!)
My head is in a whirl... ...
Read more : Clotting disorders and MS | Views : 1513 | Replies : 8 | Forum : General Discussion


Inosine & ms

URLPubmed

I take Inosine, and think it helps, but have to buy it from the U.S.,(expensive). Anyone found it in the U.K.? "RhosT" on 'ms news' points out that it is also commonly used as an anti-herpes drug, and HHV often crops up in relation to MS.

Dom.
Read more : Inosine & ms | Views : 1803 | Replies : 7 | Forum : General Discussion


Extension Study for Tovaxin

I had a request to ask about the extension study after the Phase IIb for Tovaxin. I don't remember who, but someone asked if we find out about our initial trial and whether or not we were getting the goods.

Everyone in the trial gets to participate in the extension. Everyone will find out if they were getting the drug or the placebo. I think that this is important to them as well. Anyway, I ...
Read more : Extension Study for Tovaxin | Views : 1953 | Replies : 4 | Forum : Tcelna (Tovaxin)


Minocycline & BBB effects

This may be old news to some, but its new to me. I had thought mino only worked due to its ant-inflamatory properties, but it also appears to reduce the BBB disruptions.

Minocycline Improves Neurological Outcome and Reduces BBB Disruption, Hemorrhage, and Perivascular Microglial Accumulation In Vivo
http://stroke.ahajournals.org/cgi/content/full/37/4/1087

A second agent that acts at the BBB is minocycline. Matrix metalloproteinases (MMPs) are produced during inflammation and contribute to the degradation of the basement membrane. This step ...
Read more : Minocycline & BBB effects | Views : 907 | Replies : 1 | Forum : General Discussion


New book: Next by Michael Crichton

I saw the Charlie Rose program yesterday in which he interviewed Michael Crichton about his new novel, Next. I have not read it, but it sounds good.

The author has an M.D. degree from Harvard and this book apparently deals with genetics; I have enjoyed several of his other books so I will look for this one, too.
Read more : New book: Next by Michael Crichton | Views : 3197 | Replies : 2 | Forum : Reading Nook


 

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