MMP-9s KILL the activity of ALL IFN-Betas.
It is a VERY GOOD IDEA to lower MMP-9s if taking an Ifn-Beta drug.
If you want to maximize Avonex (or any beta interferon), lowering MMP-9s will prevent it from being degraded by being cleaved into parts thus killing its Activity/Effectiveness.
http://www.cnsforum.com/commenteditem/f ... fault.aspx
Also getting the most activity from the least amount of near natural (human) interferon like Avonex will usually ...