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Natalizumab follow up

Source: American Academy of Neurology
Date: September 14, 2007

Disease Activity Increases After MS Patients Stop Drug

Science Daily — People with multiple sclerosis who stop taking the drug natalizumab may experience a rebound increase in disease activity, according to a study published September 12, 2007, in the online edition of Neurology®, the medical journal of the American Academy of Neurology.

The study involved 21 people who had MRI scans of their brains taken before ...
Read more : Natalizumab follow up | Views : 1460 | Replies : 2 | Forum : Drug Pipeline


Cellular marker

I don't remember if this was posted already or not.

Cellular Marker For Multiple Sclerosis Discovered

Source: Helmholtz Association
Date: September 1, 2007

Science Daily — In their search for the cellular and molecular causes of multiple sclerosis, an Italian-German research team has identified a subgroup of protective immune cells (suppressor cells) which are strikingly reduced in number in patients with this nervous system disorder.

These suppressor cells are characterized by a specific surface marker, ...
Read more : Cellular marker | Views : 1007 | Replies : 1 | Forum : General Discussion


Is this optic neuritis?

Hi all-

Lately, I've been feeling a little more "MSish". Some of the stuff is stuff I've had before. But, lately, I also have been feeling an odd sensation around my eyes. It is as if they are a little achy. My vision doesn't seem to get blurry, but I find myself having to make a little extra effort to focus (sorry if that doesn't make sense). FYI...I started a new job recently and my ...
Read more : Is this optic neuritis? | Views : 3188 | Replies : 17 | Forum : General Discussion


Western Blot Results and Treatment MS now Lyme ???

Hi,

I got the results of my Lyme test and started treatment.

IgeneX Western Blot:
IGM - 28 ++, 31 IND, 39 +, 41+, 58 +, 66 +, 83-93 IND.
IGG - 39 IND, 41 +, 45 +.

I started IV antibiotics (Rocethin or Rocephin???), not sure on spelling. Will be doing this 2hrs 4 days a week with evalluation/testing every 4 weeks. Lyme Doctor said with Lyme Disease the rule is for every year ...
Read more : Western Blot Results and Treatment MS now Lyme ??? | Views : 1862 | Replies : 4 | Forum : General Discussion


HE3286

Hollis-Eden reports promising results for multiple sclerosis treatment
14th September 2007

Hollis-Eden Pharmaceuticals has announced new data showing that its pre-clinical drug candidate provides benefit in an animal model of multiple sclerosis.


The company is planning to present the results evaluating HE3286 at the 2nd International Congress on Immune-Mediated Diseases being held in Moscow, Russia. The company is also presenting preclinical data demonstrating that HE3286, along with other novel compounds under investigation - HE3413 and ...
Read more : HE3286 | Views : 1473 | Replies : 2 | Forum : Drug Pipeline


Virtual reality device improves gait in MS

This press-release introduces a new devices to help MS patients improve their gait.

Here you can find the products homepage.
The complete (audio+video) device is available for 1145$.

--Frank
Read more : Virtual reality device improves gait in MS | Views : 1923 | Replies : 2 | Forum : General Discussion


Peptide which can cause autoimmunity

This article doesn't mention MS, and its relevance depends on whether you stand by the "autoimmune" theory or not, but the identification of a key part of the immune response to tissue damage sounds as if it might be important. What triggers it in the first place, and why it remains active for too long, are yet to be answered, but the fact that LL 37 is released by epithelial cells is intriguing:


Public release ...
Read more : Peptide which can cause autoimmunity | Views : 1010 | Replies : 0 | Forum : General Discussion


Genetic Predisposition

I know I brought this subject up about a year ago but there is no doubt that we have all learned a lot in the time since.

The assumption of genetic predisposition is one of the earliest and longest held assumptions in the history of modern MS research.

The assumption of genetic predisposition was/is based on incidence data showing that MS predominantly, at that time almost exclusively, affected light skinned caucasians, seemingly regardless of location ...
Read more : Genetic Predisposition | Views : 1587 | Replies : 5 | Forum : General Discussion


PPMS Seminar from John Hopkins Group

Here's a link to something rare --- a seminar on PPMS.

http://www.msleaders.org/ms-leaders/cme ... essive.asp
Read more : PPMS Seminar from John Hopkins Group | Views : 942 | Replies : 0 | Forum : General Discussion


Scared Daughter

Hi, I'm new here, but not to MS.

My mom was diagnosed when I was 8 years old, and I'm 25 now. She's had relapsing remitting for years, she could walk, but tired easily and required a cane.

She tried Avonex for a while, and it didn't do too much, so she went on Copaxone, and it did wonders, she got much stronger. She still had MS symptoms when the weather got very hot, or ...
Read more : Scared Daughter | Views : 1638 | Replies : 5 | Forum : Introductions


 

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