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More evidence of B cell involvement

Cerebrospinal Fluid B Cells Correlate with Early Brain Inflammation in Multiple Sclerosis 07 July 2008


There is accumulating evidence from immunological, pathological and therapeutic studies that B cells are key components in the pathophysiology of multiple sclerosis (MS).

Methodology/Principal Findings

In this prospective study we have for the first time investigated the differences in the inflammatory response between relapsing and progressive MS by comparing cerebrospinal fluid (CSF) cell profiles from patients at the ...
Read more : More evidence of B cell involvement | Views : 1345 | Replies : 0 | Forum : General Discussion

Copaxone 40mg

Not sure why Teva has issued this given that there appears to be no benefit in 40mg Copaxone over 20mg.

Update on Copaxone FORTE Trial in Multiple Sclerosis 07 July 2008

Teva Pharmaceutical Industries Ltd. announced top-line results from a Phase III study designed to assess the efficacy, safety and tolerability of glatiramer acetate (GA) 40mg as compared to the approved COPAXONE® 20mg in the treatment of relapsing-remitting multiple sclerosis (RRMS).
The 40mg dose ...
Read more : Copaxone 40mg | Views : 2599 | Replies : 3 | Forum : Drug Pipeline

The Multiple Sclerosis Diet Book by Roy L. Swank, MD, PhD

In reading this book again, I found ideas I wanted to post. Assuming it would be listed in the "Reading Nook," I looked here to add comments. If it is here, I can't find it; so I'll make a new entry.

For those folks who have a library of MS-related books, I recommend the first acquired book be Multiple Sclerosis: The History of a Disease by T. Jock Murray, OC, MD.

The second should ...
Read more : The Multiple Sclerosis Diet Book by Roy L. Swank, MD, PhD | Views : 3915 | Replies : 5 | Forum : Reading Nook

Temporary paralysis - ten second flashes

Hi to all,

I have a question. For about a month I'm getting partial temporary paralysis to my left hand and parts of my face - mostly lips, chin and the right eye. It happens every few (15 or so) minutes for about 10 seconds - I can't use my left hand, can't speak, I kind of freeze. After 10 seconds or so I get well again.

It's a strange feeling during the "flash" - ...
Read more : Temporary paralysis - ten second flashes | Views : 4077 | Replies : 13 | Forum : General Discussion

Can I get your opinions please?

Hi everyone,

So I am completely confused and would like some opinions. In March, I got the flu and after the flu was done, I noticed that my left side wasn't working as well as my right. I ended up going to the ER, and was admitted. I had an MRI which showed a lesion on the right side of my brain. My neurologist in the hospital seemed to think this was a viral thing. ...
Read more : Can I get your opinions please? | Views : 3480 | Replies : 17 | Forum : General Discussion

Molecule has potential to regulate immune response <:3

Please note mouse emoticon :!: ... em_id=5651

AUGUSTA, GA - When a mouse's immune system is deciding whether to reject a skin graft, one powerful member of a molecular family designed to provoke such a response can effectively reduce the visibility of the mouse's own cells and help the graft survive, researchers say.

"This is a molecule with huge potential ...
Read more : Molecule has potential to regulate immune response <:3 | Views : 1932 | Replies : 5 | Forum : Drug Pipeline

Even Canadians love Texas

Proof that even Canadians love Tx. This is something that I copy/paste from another website that I stay on (fishing). Poor guy I wish I could help him.

Finally getting a chance to see the other side of the border has been both wonderful, and agrivating at the same time.

Born and raised Canadian, I have lived and worked in western Canada my entire life, in fact until about 2 weeks ago, I had never ...
Read more : Even Canadians love Texas | Views : 1584 | Replies : 3 | Forum : Daily Life

does rrms lead to ppms?

I know this question has been asked before , but being new to the whole ms thing. Do you think that rrms leads to ppms? how many of you started out w/ rrms and then later were told it was ppms? I am only looking for answers as to what to my future holds. I know everyone is different, just looking for the general consensus. Thanks, arti
Robbie did you start out w/ rrms? hope ...
Read more : does rrms lead to ppms? | Views : 2871 | Replies : 16 | Forum : General Discussion

To Copaxone or not to Copaxone

Hi All,

My 33 year old wife is facing a decision on Copaxone and I'd be interested in people's feedback. :)

Bit of background - she had her first Optic Neuritis 11 years ago and subsequently has had one more Optic Neuritis 4 years ago and a Sensory relapse this year - so 3 relapses in 11 years. In all cases she has recovered 99%.

After the ...
Read more : To Copaxone or not to Copaxone | Views : 2433 | Replies : 8 | Forum : General Discussion


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