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Neuronal Damage in Brain Inflammation

Neuronal Damage in Brain Inflammation

Orhan Aktas, MD; Oliver Ullrich, MD; Carmen Infante-Duarte, PhD; Robert Nitsch, MD; Frauke Zipp, MD

Arch Neurol. 2007;64:185-189.


ABSTRACT

In contrast to traditional textbook paradigms, recent studies indicate neuronal damage in classic neuroinflammatory diseases of the brain, such as multiple sclerosis or meningitis. In these cases, immune cells invade the central nervous system compartments, accompanied by a massive breakdown of the blood-brain barrier and typical changes of the cerebrospinal fluid. ...
Read more : Neuronal Damage in Brain Inflammation | Views : 1166 | Replies : 0 | Forum : General Discussion


Temporary Stinging Negation - Massage

We have been on Copaxone for about 6 months. There is about 5 minutes of stinging that follows each injection. While we do clean the site with alcohol we fan it dry for more than a minute and it's not the cause of the stinging.

For Christmas we had massages.

Following the massage, NO STINGING for 2-weeks! Serioulsy. None! Now, we cannot afford to have 26 massages a year, but we tried it one more ...
Read more : Temporary Stinging Negation - Massage | Views : 1786 | Replies : 1 | Forum : Copaxone


Brain research

Another nice illustration of how much we're learning and how our understanding of the brain is evolving.



Brain works more chaotically than previously thought

March 1, 2007 - The brain appears to process information more chaotically than has long been assumed. This is demonstrated by a new study conducted by scientists at the University of Bonn. The passing on of information from neuron to neuron does not, they show, occur exclusively at the synapses, i.e. ...
Read more : Brain research | Views : 740 | Replies : 0 | Forum : General Discussion


Calcium ions and the brain

Interesting research that could have MS implications.



Calcium is spark of life, kiss of death for nerve cells

March 1, 2007 -- Oregon Health & Science University research shows how calcium regulates the recharging of high-frequency auditory nerve cells after they've fired a burst of signals, and it may have implications for neurological disorders.

The study by scientists at OHSU's Vollum Institute and the University of Arkansas for Medical Sciences, which appears in the current ...
Read more : Calcium ions and the brain | Views : 1193 | Replies : 2 | Forum : General Discussion


My possible walk for Myelin repaire Foundation

Hi
Lately I have been feeling like I need to do something in order to make it faster for these researchers to get the money they need to start pumping out the drugs. I wanted to organize a sponsored walk for the myelin Repair foundation. I have actually never done anything like that and don't really know where to start. I did email them a few days ago but have not received a reply. Tried ...
Read more : My possible walk for Myelin repaire Foundation | Views : 2139 | Replies : 8 | Forum : Daily Life


Nogo

Enabling nerve regeneration means evicting the cleanup crew

Macrophages are the immune cells that engulf and destroy the debris of damaged tissue to enable the healing process to begin. Their presence at the scene of damage is critical, but once their task is complete, it is just as critical that macrophages exit rapidly, ending the inflammatory process and making way for regrowth. In fact, the continued presence of macrophages could damage tissue, compromising repair. ...
Read more : Nogo | Views : 1168 | Replies : 4 | Forum : General Discussion


Revimmune

Accentia gets new financing, moves into MS drug market

Accentia Biopharmaceuticals Inc. said it has acquired the rights to a treatment in the late stages of development that is designed to help people with autoimmune diseases, including multiple sclerosis.

The deal calls for Accentia to pay royalties and issue stock warrants once the treatment is approved in the United States, according to a Feb. 28 filing with the Securities and Exchange Commission.

Tampa-based Accentia ...
Read more : Revimmune | Views : 3066 | Replies : 8 | Forum : Drug Pipeline


Google brain!

An interesting, but oddly unnerving, look at the brain--but it may prove useful to researchers,

http://brainmaps.org/

Dom.
Read more : Google brain! | Views : 1125 | Replies : 6 | Forum : General Discussion


Chlorinative stress

This abstract doesn't directly mention MS, but it did come up in a search about MS. I found the mention of desferrioxamine intriguing because this is a substance which chelates both aluminium and iron from the body tissues so that you excrete them in urine and faeces. Wasn't there some research recently which found high levels of aluminium in the urine of people with RRMS, and high levels of iron in the urine of people ...
Read more : Chlorinative stress | Views : 754 | Replies : 0 | Forum : General Discussion


Bullous Pemphigoid

No, I've never heard of it either, but look at the drugs listed in the second link--curious, but I suppose treatments are bound to overlap,

tinyurl

tinyurl2

Dom.
Read more : Bullous Pemphigoid | Views : 996 | Replies : 1 | Forum : General Discussion


 

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