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Oral Agents

New Oral Agents for Multiple Sclerosis, Including Novartis/Mitsubishi Pharma's Novel Drug, Will Capture 25% of Market Share by 2020
28 March 2007

Concerns Over Safety and Efficacy Will Prevent Emergence of a Blockbuster Drug Through 2020, According to a New Report from Decision Resources.

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that emerging oral therapies for multiple sclerosis, including a new drug from Novartis/Mitsubishi ...
Read more : Oral Agents | Views : 3694 | Replies : 18 | Forum : Drug Pipeline


Is Diabetes a Neurological Disease?

Lynda Carol, this one is for you.


http://medgadget.com/archives/2006/12/a ... ht_cu.html


Monday, December 18, 2006
Diabetes, A Neurological Disorder?


Remember how peptic ulcer disease was put on its head, when it was shown to have an infectious etiology, with the
discovery of H. pylori? Today we are dealing with diabetes research that is opening completely new frontiers.
In a finding that may revolutionize diabetes treatment, scientists from The Hospital for ...
Read more : Is Diabetes a Neurological Disease? | Views : 1221 | Replies : 4 | Forum : General Discussion


Regeneration project

Read more : Regeneration project | Views : 855 | Replies : 0 | Forum : General Discussion


How myelin gets mistaken

The following link to a PubMed abstract contains the usual impenetrable jargon. Here is my attempt at translation:

Two of the amino acids on a ligand, (docking molecule), of myelin basic protein are in the wrong position. They are necessary to bind with receptors on the surface of T-cells so that the myelin is not mistaken as "foreign".
Because they do not engage correctly with the T-cell, the myelin basic protein is misrecognised.
Here is ...
Read more : How myelin gets mistaken | Views : 1013 | Replies : 2 | Forum : General Discussion




Pulse steroids or estriol?

Hi all

My wife has RRMS cannot take interferons (persistent elevated liver enzymes) or Copaxone (allergic reaction after 2 months) anymore. Her neurologist, who is great, is recommending pulse steroids every 3 months.

We have agreed to this, and she is due to start another round in a few weeks, however reading up about the new estriol trial is making us wonder whether 8mg of estriol per day would be better.

Regular pulse steroids have ...
Read more : Pulse steroids or estriol? | Views : 4706 | Replies : 23 | Forum : General Discussion


Blue Brain

This project isn't immediately related to MS, but it's about eventually gaining a complete understanding of the brain.



Growing a Brain in Switzerland

Feb 16, 2007 - Der Spiegel - A network of artificial nerves is growing in a Swiss supercomputer -- meant to simulate a natural brain, cell-for-cell. The researchers at work on "Blue Brain" promise new insights into the sources of human consciousness.

The machine is beautiful as it wakes up -- nerve ...
Read more : Blue Brain | Views : 833 | Replies : 0 | Forum : General Discussion


first blood work. MRTC

Hi all,
I had my initial blood work done yesterday. Standard tests, questions and so on. I wanted to put in my 2 cents on the mrtc issue. I spoke in length about it with the clinic Neuro. I have heard a lot of theories about why folks test negative. First, my clinic has had only one negative mrtc out of six and that one had a questionable diagnosis. Only one small lesion on the ...
Read more : first blood work. MRTC | Views : 13466 | Replies : 75 | Forum : Tcelna (Tovaxin)


Gene research

Gene Behind Autoimmune Diseases Identified by Researchers 27 March 2007

A report in the March 22 issue of the New England Journal of Medicine reveals that a pinpointed region of chromosome 17, a gene named NALP1, could be a new target of treatment for autoimmune diseases. This is a particularly exciting discovery because NALP1, a gene known to control part of the immune system that serves to alert the body to viral and bacterial ...
Read more : Gene research | Views : 1698 | Replies : 13 | Forum : General Discussion


Q&A on Tysabri and Campath 1-H

Dear all,

I recently posted a presentation by Dr Coles on Tysabri and Campath. This week, Dr Coles is answering questions about Tysabri and Campath on the UK MS Society website. Tysabri is not yet approved in the UK and Campath is in trial.

Ian

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Read more : Q&A on Tysabri and Campath 1-H | Views : 1397 | Replies : 8 | Forum : General Discussion


 

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