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Rituxan® Phase II Data in Patients with RRMS

Rituxan® Phase II Data in Patients with Relapsing-Remitting Multiple Sclerosis Presented at the American Academy of Neurology

Rituxan® Significantly Reduced Signs Of Disease Activity As Measured By MRI and Relapse


BOSTON--(BUSINESS WIRE)--Genentech, Inc. (NYSE:DNA) and Biogen Idec, Inc. (Nasdaq:BIIB) announced that positive data from a Phase II clinical study of Rituxan® (rituximab) in patients with relapsing-remitting multiple sclerosis (RRMS) were presented today at the American Academy of Neurology annual meeting held in Boston. Rituxan is ...
Read more : Rituxan® Phase II Data in Patients with RRMS | Views : 1165 | Replies : 2 | Forum : Drug Pipeline




Professor Scolding

Dear all,

Professor Neil Scolding is one of the UK's leading lights in stem cell research for MS (using an individual's own stem cells). There was some talk about him starting some early trials this year and he is being funded by the UK MS Society in this area. Here is an article about his work:

Stem cell treatment may ease MS suffering

Irish Times - May. 01, 2007


The suffering of multiple sclerosis ...
Read more : Professor Scolding | Views : 1902 | Replies : 1 | Forum : Stem Cells


CERE-120 in Parkinson's

I know it doesn't mention MS but I think it's very encouraging that gene therapy is helping a neurdegenerative disease like Parkinson's. It could help us one day too.



Gene Therapy
Ceregene Presents Long Term Follow-Up Data From Phase 1 Trial of CERE-120 Demonstrating Improved Motor Function in Parkinson's Patients

April 30th, 2007

(NewsRx.com) -- Ceregene, Inc., a biopharmaceutical company, today presented long term follow-up data from a Phase 1 clinical trial of CERE-120, a ...
Read more : CERE-120 in Parkinson's | Views : 1067 | Replies : 0 | Forum : Drug Pipeline


4.5mg of LDN

I am on day three of my new LDN regiment/treatment and have been feeling pretty bad.:cry: The symptoms don't seem to be new but they are much more intense. They include sleeplessness, vertigo/dizzyness, heavyness and weakness in my legs, some foggyness and stiffness. I'm not at the point where I can attribute this only to three doses of LDN. There has been a lot ...
Read more : 4.5mg of LDN | Views : 2577 | Replies : 2 | Forum : Low Dose Naltrexone


ABX treatments and vitamin D

Are those of you on ABX treatments for MS also taking vitamin D?
And, if so, what's been your experience in healing?
Carol
Read more : ABX treatments and vitamin D | Views : 2585 | Replies : 10 | Forum : Antibiotics


Minocycline trial results

Looks good, but comes with the usual proviso, "further investigation" required.



The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study.

Mult Scler. 2007 May;13(4):517-26. Epub 2007 Feb 9.
Zabad RK, Metz LM, Todoruk TR, Zhang Y, Mitchell JR, Yeung M, Patry DG,
Bell RB, Yong VW.
Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.

Minocycline has immunomodulatory and neuroprotective activities in vitro and in an ...
Read more : Minocycline trial results | Views : 4044 | Replies : 13 | Forum : Drug Pipeline


EBV / women / smoking / genes

This research tries to tie in various MS risk factors.

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Read more : EBV / women / smoking / genes | Views : 1079 | Replies : 1 | Forum : General Discussion


Australian Neurologists knowledge of

I saw a second neurologist here in Australia today. He is running Phase III trials for both FTY720 & BG12. I was suprised when he told me he had not herd of Tovaxin at all. This is the second neurologist in Sydney that I have seen that has not herd of it. The first is my main neurologist who, from what I understaand, is one of the most respected MS neurologists in Australia.

I really ...
Read more : Australian Neurologists knowledge of | Views : 2806 | Replies : 11 | Forum : Tcelna (Tovaxin)


Micro-RNA miR-155 and immune system regulation

Here's an interesting arctile on immune system regulation from the New York Times.

NHE


Studies Reveal an Immune System Regulator
By Nicholas Wade, April 27, 2007

Scientists working independently in Cambridge, England, and Cambridge, Mass., have discovered an unexpected regulatory network that affects the entire immune system.

The regulatory network may provide new clues to both the working of the body’s immune defenses and the generation of a class of cancers known as lymphomas, which ...
Read more : Micro-RNA miR-155 and immune system regulation | Views : 933 | Replies : 1 | Forum : General Discussion


 

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