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Genetics

Interesting genetics of MS study. I expect Bromley might have something to say about this as I think part of his personal team of world-leading neurologists is involved...



A second major histocompatibility complex susceptibility locus for multiple sclerosis.

Ann Neurol. 2007 Jan 24;
Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne ...
Read more : Genetics | Views : 1084 | Replies : 3 | Forum : General Discussion


TYsabri is back!

I am glad TYSABRI is back! I was on it once in January 2 years ago. I took my husband to NY for his 40th birthday in February and remember waking up that Saturday (2 weeks after my infusion) and turning to my husband and saying "I feel normal" I kept waiting for side effects and they never came. It was pulled off of the market right before my second treatment. I was bummed and ...
Read more : TYsabri is back! | Views : 1832 | Replies : 2 | Forum : Tysabri (Antegren or Natalizumab)


Neural stem cells

Biomed firm commercialises stem-cell sales

A U.S. biomedical company said Thursday it reached an agreement to commercialise the distribution of neural stem cells by the billions.
'We`re going to be able to distribute a cell that has the ability to produce all the different cell types in the nervous system,' Aruna Biomedical Inc. Chief Executive Steven Stice told the Atlanta Journal-Constitution.

Stice developed neural progenitor cell technology at the University of Georgia, where he ...
Read more : Neural stem cells | Views : 1604 | Replies : 3 | Forum : Stem Cells


yucko

oh great. to add to my list of fun things to deal with, now i have a staphylococcus aureus infection. it's hard to research because it's normally hanging out on us anyway, and also because of the food-poisoning and methicillin resistant blabbedy-blah all over google. the connection i've found so far: neutrophil leukocytes. but i don't understand, and i'm tired of trying to figure it all out. is this what has been screwing up my ...
Read more : yucko | Views : 2449 | Replies : 7 | Forum : Daily Life


CHR-1103

Chromos reports preclinical data in support of CHR-1103 as an acute therapy for relapse associated with multiple sclerosis
Brain Pathology paper has implications for treatment of MS.

Chromos Molecular Systems Inc. announced today the publication of a paper entitled "Modulation of Experimental Autoimmune Encephalomyelitis by VLA-2 Blockade" in the peer-reviewed scientific journal, Brain Pathology. This paper, authored in collaboration with Dr. Robert Fujinami of the University of Utah School of Medicine, demonstrates that a monoclonal ...
Read more : CHR-1103 | Views : 1345 | Replies : 3 | Forum : Drug Pipeline


Antibodies to myelin

Antibodies to Myelin Don't Signal MS

By Neil Osterweil, Senior Associate Editor, MedPage Today
Reviewed by Rubeen K. Israni, M.D., Fellow, Renal-Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine
January 24, 2007


Basel, Switzerland, Jan. 24 -- Contrary to a previous report, the presence in the blood of two types of antibodies to myelin is not diagnostic of multiple sclerosis, investigators here reported.

Nor does the presence of the antibodies indicate a risk ...
Read more : Antibodies to myelin | Views : 4416 | Replies : 39 | Forum : General Discussion


RTL 1000

Artielle ImmunoTherapeutics, Inc., and QSV Biologics, Ltd. Sign Contract for cGMP Manufacture of RTL 1000 for Multiple Sclerosis
22 Jan 2007
Announced today the signing of a contract for the process development and cGMP manufacturing of RTL 1000 for multiple sclerosis.

EDMONTON, Canada | Jan 22, 2007 | QSV Biologics, Ltd (QSV), a North American based biologics CMO located in Edmonton, Canada, and Artielle ImmunoTherapeutics, Inc., (Artielle) a privately held autoimmune therapeutics company located in ...
Read more : RTL 1000 | Views : 1624 | Replies : 0 | Forum : Drug Pipeline


Bone Marrow Stem Cells

Stem Cells Cultured From Human Bone Marrow Behave Like Those Derived From Brain Tissue

Stem cells taken from adult human bone marrow have been manipulated by scientists at the Maxine Dunitz Neurosurgical Institute at Cedars-Sinai Medical Center to generate aggregates of cells called spheres that are similar to those derived from neural stem cells of the brain.
In addition, the bone marrow-derived stem cells, which could be differentiated into neurons and other cells making ...
Read more : Bone Marrow Stem Cells | Views : 1252 | Replies : 0 | Forum : Stem Cells


Dating Challenges

hello to all,

while i've posted a few comments, i've probably been more of an observer...i've read a lot of poignant and touching comments by many members and thought i would vent a little bit. i am a thirty-something year old guy who had one significnat attack about 2 years ago. i was pretty sick for about a year, but eventyually slowly recovered. these days, i've been pretty fortunate in that i only have a ...
Read more : Dating Challenges | Views : 1427 | Replies : 4 | Forum : General Discussion


St Jude study

Chopping Off Protein Puts Immune Cells Into High Gear


St. Jude study shows LAG-3 protein on activated T lymphocytes slows replication until ADAM10 and ADAM17 enzymes cleave it off to allow these cells to reproduce rapidly

MEMPHIS, Tenn., Jan. 24 /PRNewswire/ -- The complex task of launching a well-organized, effective immune system attack on specific targets is thrown into high gear when either of two specific enzymes chop a protein called LAG-3 off the immune ...
Read more : St Jude study | Views : 807 | Replies : 0 | Forum : General Discussion


 

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