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TNF-alpha and INF-gamme increases after Tysabri treatment

After 6 month open lable trial with Tysabri, patients expressed higher levels of TNF-alpha and INF-gamma in peripheral blood.

Abstract

--Frank


MBP 8298

The following article includes some possible dates when MBP 8298 will be launched.

Eli Lilly has been cleared to license BioMS Medical's multiple sclerosis drug MBP8298.

The US Federal Trade Commission has cleared the global licensing and development agreement that grants Eli Lilly exclusive worldwide rights to BioMS Medical's lead multiple sclerosis compound, MBP8298. This represents a major step forward for Lilly, as the company looks to diversify its traditionally psychiatry-focused CNS offerings by expanding ...
Read more : MBP 8298 | Views : 1948 | Replies : 4 | Forum : Drug Pipeline


Contribution of relapses to disability

A big question in MS is the connection (if any) between relapses and disability (long term). Trials involving drugs which are very effective at stopping / reducing relapses (Campath, Mitoxantrone etc) should provide answers as to whether substantially reducing relapses has long term benefits (such as substantially slowing down disability / stopping the progression of disability). The following research examines the relationship of relapses and disability.

Ian

http://www.msif.org/en/research/ms_rese ... _disa.html ...
Read more : Contribution of relapses to disability | Views : 1160 | Replies : 0 | Forum : General Discussion


WalkAide on Good Morning America

Check out the following link for a story about a fellow MSer and her experience with the WalkAide

http://abcnews.go.com/GMA/OnCall/story? ... 183&page=1

I continue to have a very positive experience with my WalkAide - glad that I spent the money. Hopefully, the insurance companies will decide to start some type of coverage for the device.

For those who are interested, you can go to a Hanger Prosthetic Clinic and try ...
Read more : WalkAide on Good Morning America | Views : 6213 | Replies : 8 | Forum : Medical Devices


123

123
Read more : 123 | Views : 1661 | Replies : 1 | Forum : Revimmune (cyclophosphamide or cytoxan)


Hidden Clothes

Image
Read more : Hidden Clothes | Views : 1727 | Replies : 0 | Forum : Humor


4-AP (Fampridine-SR) passes FDA heart test

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Acorda Therapeutics (nasdaq: ACOR - news - people ) said its multiple sclerosis drug Fampridine-SR does not raise the risk of heart-related side effects anymore than a placebo in a so-called QT cardiac safety study required by the U.S. Food and Drug Administration. Acorda shares were up 20.1%, or $4.38, at $26.16, in afternoon trading.
Read more : 4-AP (Fampridine-SR) passes FDA heart test | Views : 1473 | Replies : 0 | Forum : Drug Pipeline


Newly Diagnosed and Untreated? We'd like you to give blood.

Accelerated Cure Project for MS is seeking out individuals who meet
the following criteria in order to fulfill a sample and data request
from researchers at NASA.

The researchers at NASA will be using repository samples to perform
pathogen and gene expression analyses in an effort to provide insight
into one of the potential causes of MS.

There are no drugs involved, only a blood draw and extensive
interview.

Criteria:

* Diagnosed MS within the ...
Read more : Newly Diagnosed and Untreated? We'd like you to give blood. | Views : 3650 | Replies : 17 | Forum : General Discussion


Lyon - video

Bob,

I'm glad to see that my threats to ban you from this site have resulted in a dramatic reduction in the number of your postings (reduction of c.30% - the equivalent of a CRAB drug).

I attach a video for you to watch. I don't have 12 minutes to spare so would be grateful for your summary of the main points. So when you get home tonights, no porn videos, no Dukes of Hazzard ...
Read more : Lyon - video | Views : 2095 | Replies : 13 | Forum : General Discussion


Injection location and side effects

Anyone find a correlation between the injection location and intensity of side effects?

I am definitely starting to see a pattern. When I inject in my stomach, the next day isn't so bad. But when I inject in my leg, it's horrible - every time.

I'm now at the point where I only inject my leg once a week, on Friday night, because otherwise I wouldn't make it to work the next morning. My poor ...
Read more : Injection location and side effects | Views : 2440 | Replies : 2 | Forum : Rebif


 

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