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I was involved in clinical trial on CNTO1275 (centocor) and I should have had final mri in April of this year, but the doctor said me about premature end of the trial. She didn´t say me the reason and I didn´t ask, because I had too much to solve with the doctor that time. So finally, does anybody know, where to find any results of this trial please? I wasn´t successful in finding it ...
Read more : cnto1275 | Views : 1740 | Replies : 1 | Forum : Drug Pipeline

Anybody else on Firategrast?

I started on a clinical trial 28 May and was wondering if anybody else was taking it?
Read more : Anybody else on Firategrast? | Views : 14375 | Replies : 38 | Forum : Drug Pipeline

Hi everyone - just an intro & quick quuestion

Hi there

I am a bit new to the site, but have been reading all the great info for a while - hope you don't mind if I join in? This site seems to be a fantastic font of information, and I admit to my ignorance! I am fortunate enough to have a husband, and am enjoying raising our two little boys, and am still working full time as I have all my life, though ...
Read more : Hi everyone - just an intro & quick quuestion | Views : 2018 | Replies : 7 | Forum : Introductions

Protein research

Prof Steinman is presenting at the MS Frontiers conference in London this week so may provide more detail on this research.

Stanford researchers clarify protein's role in multiple sclerosis 13 June 2007

A protein found primarily in the lens of the eye could be the critical "tipping point" in the spiral of inflammation and damage that occurs in multiple sclerosis, researchers at the Stanford University School of Medicine report.
This protein - alphaB-crystallin - ...
Read more : Protein research | Views : 950 | Replies : 2 | Forum : General Discussion

Cladribine - one for Lyon


Now that you have ditched that dreadful shiny shirt and have signed up to the hair-transplant, I thought I'd reward you the research results you like to see.

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Read more : Cladribine - one for Lyon | Views : 1146 | Replies : 1 | Forum : General Discussion

Tovaxin News

This recent press release from Opexa suggests that they may be improving their methods of making the vaccine. Hopefully, this will increase the efficacy of the current vaccine and, in the future, help get people into the Phase III study more quickly once it begins.


Opexa Presents Tovaxin™ Research at Federation of Clinical Immunology Societies Annual Meeting
June 11, 2007 07:00 AM Eastern Daylight Time

THE WOODLANDS, Texas--(BUSINESS WIRE)--Opexa Therapeutics, Inc. (NASDAQ:OPXA), a ...
Read more : Tovaxin News | Views : 1928 | Replies : 1 | Forum : Tcelna (Tovaxin)

Histamine research

Central histamine H3 receptor signaling negatively regulates susceptibility to autoimmune inflammatory disease of the CNS. 13 June 2007

Histamine (HA), a biogenic amine with a broad spectrum of activities in both physiological and pathological settings, plays a key regulatory role in experimental allergic encephalomyelitis, the autoimmune model of multiple sclerosis. HA exerts its effect through four G protein-coupled receptors designated HA receptor H1, H2, H3, and H4.
We report here that, compared with wild-type ...
Read more : Histamine research | Views : 2768 | Replies : 20 | Forum : General Discussion

Emotions gone this relapse?

I'm usually v. good at knowing what's a relapse and what's not - after 9 + years with the MonSter I should be!.

I seem to be crying at very small things. In work this has happened a few times recently. Feel very "teary" today and feel like I am raw emotionally. I know a lot's going on for me and DH right now (I am off Copax last 2 months as trying for ...
Read more : Emotions gone this relapse? | Views : 2023 | Replies : 12 | Forum : General Discussion

Experiences on supplementing homones?


After reading various studies, indication a link between hormone levels and the dissease course of MS decided to get my hormon levels tested.

My results are:
Estradiol: 14,9pg/ml Norm: 11,6 - 41,2
Testosteron: 5,4ng/ml Norm: 4,0 - 9,0
DHEA-S: 206,0mcg/ml Opt: 250 - 400

My GP said, if I wanted to he would subscribe testosteron and estradiol gels to get my values to the upper norm levels.
I'm not sure yet, but basicly ...
Read more : Experiences on supplementing homones? | Views : 1563 | Replies : 3 | Forum : Natural Approach

Hormone Study - understanding/translation problem


could someome please help me to understand the results of that study, I think I have problems with the translation:

Link PubMed

RESULTS: Serum testosterone was significantly lower in women with MS than in controls. The lowest levels were found in women with a greater number of gadolinium enhancing lesions. A positive correlation was observed between testosterone concentrations and both tissue damage on MRI and clinical disability.
In men, there was a positive ...
Read more : Hormone Study - understanding/translation problem | Views : 1508 | Replies : 8 | Forum : General Discussion


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