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MRI Accuracy

This is a very interesting study that questions the accuracy of MRIs in diagnosing MS. Isn't one of the measures in the clinical trials of all these MS drugs the number of lesions that appear on an MRI??!! Hmmm...



Study Questions The Accuracy Of MRI In Diagnosis Of MS After First Neurologic Event

The accuracy of magnetic resonance imaging might not be great enough to confirm a diagnosis of MS, based ...
Read more : MRI Accuracy | Views : 1168 | Replies : 1 | Forum : General Discussion


It might as well be written in Chinese, but it looks as if another company is looking at possbible therapies for MS and other neurological diseases - which must be good.
Read more : KineMed | Views : 1275 | Replies : 1 | Forum : Drug Pipeline

Conditions under which Tysabri will come back to market

I posted this in another thread just now, but figured it might need it's own thread. This is a March 27th update regarding the return of Tysabri:


"....Its key recommendations for approval include:

• Tysabri be made available only to patients who have enrolled along with their physicians in a mandatory registry program;

• Tysabri be made available only to patients diagnosed with relapsing MS;

• ...

Completed Phase II trial of oral IFN-alpha

Interesting that this talks about a completed phase II trial of an oral treatment. I hope if they do another trial it will be phase III.

Ingested (oral) IFN-alpha represses TNF-alpha mRNA in relapsing-remitting multiple sclerosis.

J Interferon Cytokine Res. 2006 Mar;26(3):150-5.
Brod SA, Nguyen M, Hood Z, Shipley GL.
Department of Neurology, University of Texas-Houston, Health Science Center (UTHHSC), Houston, TX 77030, USA.

In a phase II trial ...
Read more : Completed Phase II trial of oral IFN-alpha | Views : 1586 | Replies : 2 | Forum : Drug Pipeline

Light sensitivity?

For the past couple of years I've noticed that I'm becoming increasingly more sensitive to bright lights usually while I'm driving at night. Since this typically occurs on the days that I take Avonex, which I've been on for just about 6 years, I've attributed it to a side effect of the medication. However, I also have light sensitivity problems on other nights during the week as well. It just seems to be worse on ...
Read more : Light sensitivity? | Views : 2828 | Replies : 1 | Forum : Avonex

Treatments for Neuropathic Pain

Just wondering what some MSers experiences with AED's used for neuropathic pain has been? Seems that the new medicine by Pfizer that is recommended for use in neuropathic pain makes my vertigo and balance worse. Any others that have had similar experiences? And regarding neuropathic pain,, what are some of the meds or things that seem to provide benefit without making one have that "disconnected from the body feeling" or is this just a trade-off ...
Read more : Treatments for Neuropathic Pain | Views : 2104 | Replies : 6 | Forum : General Discussion

echinacea for ms!?!

i think i'm going to guinea pig myself and try it! if the auto-immune theory is disputed, and if the home page article says more natural killer cells are good, then hell yea! i'd say that speaks to the good ol' virus theory, wot wot? i'm throwing immune system caution to the wind and takin me some echinacea.

Biogerontology. 2005;6(3):157-63.
Enhancement of natural killer cells and increased survival of aging mice fed daily Echinacea root ...
Read more : echinacea for ms!?! | Views : 1767 | Replies : 8 | Forum : General Discussion

Understanding MS 101: Doctor Talk and People Talk

In trying to explore various issues relating to supplements, I realized that I needed a more detailed understanding of just how exactly MS works and demyelination comes to be. So this is a thread that is strictly for trying to understand what is known and unknown about how the disease process happens. I realize that a lot of you understand all this, but for me (and I figure there are a few more others like ...
Read more : Understanding MS 101: Doctor Talk and People Talk | Views : 11995 | Replies : 19 | Forum : General Discussion

More research

The NMSS has announced even more funding for MS research. You can't say they aren't trying!

Read more : More research | Views : 917 | Replies : 0 | Forum : General Discussion

Any SP MSer's take Tysabri?

Did anyone take Tysabri that was SP? And did it improve you any? I thought I had read about some that did.
Read more : Any SP MSer's take Tysabri? | Views : 2658 | Replies : 10 | Forum : Tysabri (Antegren or Natalizumab)


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