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2017: Deceptive curcumin offers cautionary tale for chemists

Deceptive curcumin offers cautionary tale for chemists
Spice extract dupes assays and leads some drug hunters astray.

https://www.nature.com/news/deceptive-c ... ts-1.21269

Inside the golden-yellow spice turmeric lurks a chemical deceiver: curcumin, a molecule that is widely touted as having medicinal activity, but which also gives false signals in drug screening tests. For years, chemists have urged caution about curcumin and other compounds that can mislead naive drug hunters.

Now, in ...
Read more : 2017: Deceptive curcumin offers cautionary tale for chemists | Views : 126 | Replies : 0 | Forum : Natural Approach


MS in Canada and the Americas

not hot off the presses, but new to me - interesting

Regional variation of multiple sclerosis prevalence in Canada (2005)
http://journals.sagepub.com/doi/abs/10. ... 05ms1192oa

Abstract
Objective: To describe the regional distribution of multiple sclerosis (MS) prevalence in Canada, controlling for age and sex. Methods: This study used data from the Canadian Community Health Survey, a large general health survey (n=131,535) conducted in 2000/2001. Subjects aged 18 and over were included ...
Read more : MS in Canada and the Americas | Views : 155 | Replies : 0 | Forum : General Discussion


interesting: real time world air quality map

Real Time World Air Quality Index
https://waqi.info/
Read more : interesting: real time world air quality map | Views : 194 | Replies : 3 | Forum : General Discussion


Mapped: the global epidemic of 'lifestyle' disease in charts

worth a look; some quite interesting graphics

Mapped: the global epidemic of 'lifestyle' disease in charts (2018)
https://www.telegraph.co.uk/news/0/mapp ... se-charts/

Non-communicable diseases (NCDs) such as heart disease, cancer and diabetes now account for 90 per cent of deaths each year in the UK.

These so-called 'lifestyle' conditions are a well known problem in the west. Much less understood is that they now account for the majority (53 per cent) ...
Read more : Mapped: the global epidemic of 'lifestyle' disease in charts | Views : 160 | Replies : 0 | Forum : General Discussion


2017 study: Living near major roads not associated with MS

Living near major roads and the incidence of dementia, Parkinson's disease, and multiple sclerosis: a population-based cohort study
https://www.sciencedirect.com/science/a ... 3616323996

Summary
Background
Emerging evidence suggests that living near major roads might adversely affect cognition. However, little is known about its relationship with the incidence of dementia, Parkinson's disease, and multiple sclerosis. We aimed to investigate the association between residential proximity to major roadways and the incidence of these ...
Read more : 2017 study: Living near major roads not associated with MS | Views : 135 | Replies : 0 | Forum : General Discussion


Not enough sunlight?

I guess I am having one of my bad days. Waiting on my son's MRI next week. I know he doesn't have a
diagnosis yet but I feel sure it's MS. Every now and then the thought enters my mind~did I not put him
out in the sun enough? Is this my fault. I read posts where people have never heard of this disease until they
got it. I remember hearing of it, but it ...
Read more : Not enough sunlight? | Views : 202 | Replies : 5 | Forum : General Discussion


Prophylactic treatment against GM-CSF

2018 Sep 14
Ludwig Cancer Research, Brussels Branch, Brussels, Belgium
Prophylactic treatment against GM-CSF, but not IL-17, abolishes relapses in a chronic murine model of multiple sclerosis
https://www.ncbi.nlm.nih.gov/pubmed/30216414

Abstract
The pathogenic role of IL-17 and GM-CSF has been unravelled in experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS). However, in most models, EAE is characterised by a monophasic attack which is not representative of the relapsing ...
Read more : Prophylactic treatment against GM-CSF | Views : 162 | Replies : 0 | Forum : General Discussion


ON or something else?

Hi everyone,

It seems like im in high alert for any new symptoms or changes in my body while I await my mri results that Im panicking over everything I think could be an MS symptoms. For those who have had Optic Neuritis, is a slightly swollen upper eyelid (not right by the lashes but more below the brow) is part of ON? i dont think so but all of a sudden yesterday I had ...
Read more : ON or something else? | Views : 182 | Replies : 5 | Forum : Undiagnosed


Promise for myelin repair in multiple sclerosis

2018 Sep 13
Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
In vivo conversion of astrocytes into oligodendrocyte lineage cells with transcription factor Sox10; Promise for myelin repair in multiple sclerosis
https://www.ncbi.nlm.nih.gov/pubmed/30212518

Abstract
Recent studies demonstrate that astroglial cells can be directly converted into functional neurons or oligodendrocytes. Here, we report that a single transcription factor Sox10 could reprogram astrocytes into oligodendrocyte-like ...
Read more : Promise for myelin repair in multiple sclerosis | Views : 215 | Replies : 0 | Forum : General Discussion


MS or Chronic Somatic Symptom Disorder?

Hello everyone! I have been having a totally loss of body sensation since 2013, it started on my right side and also occasional weakness. Eventually, it spread over to my left side ( I have no loss in temperature, pain, or any motor issues) the feeling has gotten progressively worse over time with periods where the symptoms stay as they are. I have had countless blood tests, lower back ultra sound, brain MRI, nerve conduction ...
Read more : MS or Chronic Somatic Symptom Disorder? | Views : 222 | Replies : 4 | Forum : Undiagnosed


 

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