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I'm noticing a lot of research abstracts mentioning p53 lately. I don't have a clue what it is, but if you look through old posts at ThisIsMS, you'll see some threads from OddDuck and BioDocFL talking a bit about it. I also just saw this abstract from last year from Vanderbilt and one of the oft-referenced researchers around here, Sriram.

Defective ATM-p53-mediated apoptotic pathway in multiple sclerosis.

Ann Neurol. 2005 Oct;58(4):577-84.
Deng X, Ljunggren-Rose A, ...
Read more : p53 | Views : 1285 | Replies : 3 | Forum : General Discussion

More on EBV

We haven't had nearly enough posts on EBV in the last couple of weeks. I hope this article hasn't already been posted.

Epstein-Barr virus may increase risk of multiple sclerosis

Researchers have found that patients with multiple sclerosis carry a population of immune cells that overreact to Epstein-Barr virus.
The virus, which causes mononucleosis and may contribute to some cancers, has long been suspected to play a role in multiple sclerosis. However, the mechanism linking ...
Read more : More on EBV | Views : 1062 | Replies : 3 | Forum : General Discussion


Dear all,

A bit more news on CHR 1103 - it's in pre-clinical but has put together an impressive advisroy board.


Chromos announces independent Multiple Sclerosis Advisory Board

Chromos Molecular Systems Inc. has formed a Multiple Sclerosis (MS) Advisory Board to guide the Company's development of a promising novel treatment for MS. Comprised of nationally and internationally recognised physicians, clinicians and scientists in the MS field, the MS Advisory Board will serve as ...
Read more : CHR-1103 | Views : 1270 | Replies : 1 | Forum : Drug Pipeline

New animal model

A Beautiful New Model For MS
05 Sep 2006

Multiple sclerosis (MS) is a disease that affects the cells of the brain and spinal cord. MS can cause various symptoms, including depression, pain, and impaired mobility. Although it is clear that MS is caused by cells of the immune system inappropriately attacking the cells of the brain and spinal cord, much remains unknown about the disease. For example, what triggers the immune cells to attack; ...
Read more : New animal model | Views : 1665 | Replies : 4 | Forum : General Discussion

TENS machine

Hello out there fellow MSers! Has anyone heard of or tried using a TENS machine to rebuild a muscle or muscle group? The central nervous system is affected, often the peripheral nerves are preserved. A Tens machine should function and help build muscle strength it seems. I am thinking of trying it. So, your experience would be greatly appreciated, thanks. Carolew :?
Read more : TENS machine | Views : 7948 | Replies : 19 | Forum : General Discussion

Statins etc

The UK MS Society provides information on leading UK MS researchers. Attached is the current profile on their website, which is of interest because it mentions statins and also his view that combo treatments are probably the way forward. Although for the life of me I can't imagine anything more boring than studying the blood brain barrier for 16 years (more than some 'life sentences' for murder!). I bet he has some riveting conversations over ...
Read more : Statins etc | Views : 857 | Replies : 1 | Forum : General Discussion

Neuroprotectants 2005-2020

Drugs from Astrazeneca/Renovis and Sanofi-Aventis Have the Potential to Revolutionize the Treatment of Several Neurologic Indications

Tuesday September 5, 8:00 am ET

New Drug Launches Will Propel Neuroprotectant Sales to Nearly $3 Billion in 2020, According to a New Report from Decision Resources

WALTHAM, Mass., Sept. 5 /PRNewswire/ -- Decision Resources, Inc., one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that neuroprotectants, including drugs from AstraZeneca/Renovis and Sanofi-Aventis, ...
Read more : Neuroprotectants 2005-2020 | Views : 1149 | Replies : 2 | Forum : Drug Pipeline


My doctor wants me to start Novantrone. I am a little leary about this. It has some pretty sacry side feects. My doctor old me that he had some patients try LSN and none of them found it to be helpful. Anyone that has tried or is on Novantrone, I would apprecaite comments.
Read more : novantrone | Views : 3276 | Replies : 2 | Forum : Low Dose Naltrexone

Medicare part B

I have read all posts and have not found the answer to my question. Maybe, somebody here knows.

Medicare part "B" will cover Ty. How much of the 2,8?? will they pay? The infusion center will also charge. Is that covered?

Read more : Medicare part B | Views : 1872 | Replies : 4 | Forum : Tysabri (Antegren or Natalizumab)


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