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Ok...........the following pertains to Huntington's disease, but it also provides a short explanation with regard to apoptosis (which as we all know, we want to inhibit apoptosis in MS). And we all know how integral that Ca2 influx plays in axonal degeneration in MS, also.

Read the highlighted portions below and you will see how what they are saying also relates to apoptosis in MS.

(Hey...........blame Robin for getting me started here today. ...
Read more : Apoptosis | Views : 2252 | Replies : 16 | Forum : General Discussion

ROBIN: Let's get "technical". Get this!

Robin, (and others), is something interesting. For those who know and followed my, Robin and Wesley's highly technical discussions in 2004 and 2005, you all will probably understand this. If not, you might not understand.

For once, though, I'm not going to go into overdrive with my usual explanations, etc.

I just know that Robin may find this particularly interesting. Especially when he sees the word "microglia". :wink: ...
Read more : ROBIN: Let's get "technical". Get this! | Views : 933 | Replies : 2 | Forum : General Discussion

Come back Deb all is forgiven

This forum used to be a very good place to visit and objectively discuss current MS research. Unfortunately that is no longer the case.

These days each news item is used to either complain at the lack of progress in finding a cure for MS or to promote the ABX regimen. I'm happy for those that are following the regimen and are getting good results but there are others getting good results from different treatments ...
Read more : Come back Deb all is forgiven | Views : 1497 | Replies : 9 | Forum : General Discussion

A new angle: using RNA

This sounds like a different way of treating MS that has potential.

A Novel Method of Modifying Immune Responses By Vaccination With Lipiodol-siRNA Mixtures.

J Transl Med. 2006 Jan 3;4(1):2
Ichim TE, Popov IA, Riordan NH, Izadi H, Zhong Z, Yijian L, Sher S, Oleinik EK.

ABSTRACT: The dendritic cell (DC) possesses the ability to stimulate both T helper 1 (Th1) and Th2 responses depending on activation stimuli. Although it is ...
Read more : A new angle: using RNA | Views : 1119 | Replies : 0 | Forum : Drug Pipeline

Stem cells for immunosuppression and neuroprotection

I hope they can quickly push stem cell treatments along the road to clinical trials...

Stem cells in inflammatory demyelinating disorders: a dual role for immunosuppression and neuroprotection.

Expert Opin Biol Ther. 2006 Jan;6(1):17-22.
Uccelli A, Zappia E, Benvenuto F, Frassoni F, Mancardi G.
Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via De Toni 5, 16132 Genoa, Italy.

In recent years much excitement has been generated over ...
Read more : Stem cells for immunosuppression and neuroprotection | Views : 1189 | Replies : 0 | Forum : Stem Cells

Infectious cause

Dear all,

As most of you know I'm not a believer in the auto-immune theory of MS. I have no medical training etc but rely on basic observation. Inflammation is the body's response to something e.g. if you cut your finger it becomes inflammed as the immune system targets any foreign invaders. My gut feeling tells me that the same must be true with MS. Something is happening in the CNS and the immune system ...
Read more : Infectious cause | Views : 3233 | Replies : 29 | Forum : General Discussion

Insurance Company Denial

Atlantic Blue Cross has denied my claim for LDN. I submitted a special authorization form (after it was denied the first time) that the neurologist filled out, and they still won't allow me to put my prescription costs for LDN through for reimbursement. It reads "Established payment criteria indicates that Revia is not reimbursed for treatment of MS".

There are so many things wrong with this. First of all, shouldn't the medical "professionals" decide what ...
Read more : Insurance Company Denial | Views : 2145 | Replies : 2 | Forum : Low Dose Naltrexone

Try Again

I wish i could just try everything out there that might help, but unfortunately all the new and maybe promising treatments have to go through the government testing which takes a long time ,probably longer than alot of us have before the claws of ms really take hold.I would say from all you read it looks promising for future msers but i guess people back in the 70's and 80's said the same thing. Somtimes ...
Read more : Try Again | Views : 1809 | Replies : 0 | Forum : Low Dose Naltrexone

Stem Cell Treatments and MS

Hi all,

We at the MSRC are putting together an expanded section on Stem Cell Treatments, and as part of that, and for New Pathways Magazine, I am looking for people who are considering having, or have had SCT for their MS to provide personal feedback on the various companies and their experiences, whether it helped or not, how you were treated (hopefully you get the picture).

I already have some personal stories at ...
Read more : Stem Cell Treatments and MS | Views : 1486 | Replies : 0 | Forum : Stem Cells


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