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upcoming challenge! eek!

okay, well i've slowly built up my walking over the last six months. i still find that my lower back and butt gets tingly when i walk, even for just a few minutes - particularly on paved surfaces. and i don't tend to walk for more than an hour or two at once even when i'm on a nice soft trail. these days, i can climb out of pretty deep ravines without my legs getting ...
Read more : upcoming challenge! eek! | Views : 2111 | Replies : 7 | Forum : Daily Life


Dignan's famous

Surfing on the web I came across the list that Dignan created - I think in Arabic.

You should be getting royalites Dignan.

Ian

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Read more : Dignan's famous | Views : 1664 | Replies : 4 | Forum : Drug Pipeline


pirfenidone

Treatment for MS - Hope

For years, Sarah Moore endured slurred speech, difficulty moving and constant exhaustion after being diagnosed with multiple sclerosis in 1975.
Desperate for any way to stop the disease's progression, the former teacher was the first user of Deskar, an investigational drug developed by Dallas pharmacologist Solomon B. Margolin and tested by neurologist Dr. Jonathan E. Walker, medical director at Neuroscience Centers in Dallas.

Now Moore, who had to use a ...
Read more : pirfenidone | Views : 1175 | Replies : 1 | Forum : General Discussion


Cladribine

I recently received the following invite to apply to take part in a clinical trial and was wondering if anyone had either heard of it or had any views on it.

The CLARITY Study


It’s about the freedom to choose the treatment that works best for you. That’s why researchers are studying an oral form of an investigational medicine (a tablet) to determine whether it is safe and effective in treating relapsing-remitting multiple sclerosis.

The ...
Read more : Cladribine | Views : 1366 | Replies : 3 | Forum : General Discussion


Physical Rehabilitation and MS

I know I have probably whined too much on this site about the state of MS drug development and the usefullness of existing drugs. I'll probably continue to complain about all that. In the meantime, however, I have been seeing a few interesting articles about physical rehabilitation in MS patients. I became interested about exercise when I saw on TV a few months ago a show about a man in his 60s with Parkinson's disease ...
Read more : Physical Rehabilitation and MS | Views : 1642 | Replies : 8 | Forum : General Discussion


simple question

Why don't they prescribe anti-inflammatories like naprosyn or ibuprophen to us? They use steroids to stop the inflammation if we have an attack. They like the anti-inflammatory effect of many new drugs. They are trying to stop the damage of the inflammation of the myelin....
We use anti-inflammatories when people have migraines so they do reach the brain.
I may have missed the explanation before I joined this forum. I will ask my neuro on ...
Read more : simple question | Views : 1244 | Replies : 4 | Forum : General Discussion


Proteomics

Interesting article from the economist that isn't specifically about MS, but about neurodegenerative diseases in general.



From The Economist:

July 6, 2006 -- After the genome, the proteome! That was the cry when the scientific bigwigs running the Human Genome Project were asked what came next. Proteomics—identifying the structure and abundance of all of the proteins in an organism, as genomics sought to identify all of the genes—is a harder and more open-ended task. But, ...
Read more : Proteomics | Views : 735 | Replies : 0 | Forum : General Discussion


...and now...the hair loss...

Well...I guess I can not deny it anymore...I am loosing my hair. I think it is because of the Avonex but my Dr. wants to run some tests. I am not sure what to hope for. Do I want it to be Avonex which I THINK is helping me or do I want it to be something else???? What would I pick? This is going to be really vain but I love my hair. I ...
Read more : ...and now...the hair loss... | Views : 7130 | Replies : 26 | Forum : Daily Life


Th17 (3rd subtype of white blood cell)

This is a very interesting discovery

"For decades, Th1 and Th2 were the twin middlemen of the human immune system. Scientists knew that these two subtypes of white blood cells activated and directed other immune cells in fighting viral, bacterial and fungal infections, and even some cancers.

Thus, the processes surrounding Th1 and Th2 were attractive targets for researchers working on new treatments.

But as it turns out, the twins may be triplets, a development ...
Read more : Th17 (3rd subtype of white blood cell) | Views : 1645 | Replies : 10 | Forum : General Discussion


Tetramers

Seattle in demand on even a molecular level - Tetramers

Widely sought tetramers help diagnose disease.

Thanks to Dr. Jerry Nepom and his gang of scientists at a research facility few people might know by name, Seattle provides much of the world with a spiderlike molecule that has become one of the research community's hottest new tools.

Tetramers are artificial molecules with four arms that can seek out and latch on to specific targets in ...
Read more : Tetramers | Views : 753 | Replies : 0 | Forum : General Discussion


 

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