Neuronal Damage in Brain Inflammation
Orhan Aktas, MD; Oliver Ullrich, MD; Carmen Infante-Duarte, PhD; Robert Nitsch, MD; Frauke Zipp, MD
Arch Neurol. 2007;64:185-189.
In contrast to traditional textbook paradigms, recent studies indicate neuronal damage in classic neuroinflammatory diseases of the brain, such as multiple sclerosis or meningitis. In these cases, immune cells invade the central nervous system compartments, accompanied by a massive breakdown of the blood-brain barrier and typical changes of the cerebrospinal fluid. ...