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Avonex plus Doxycycline trial preliminary results

An abstract from the AAN meeting about the combination trial of doxycycline and Avonex. The preliminary, small sample results look promising.



Combination Therapy with Intramuscular Interferon Beta-1a and Oral Doxycycline in Patients with Multiple Sclerosis: An Open-Label Trial

Alireza Minagar, J. Steven Alexander, Rhonda Brooks, Roger E. Kelley, Robert N. Schwendimann, Eduardo Gonzalez-Toledo, Dana Merrill Bryan, Shreveport, LA

OBJECTIVE: To determine the safety, tolerability, and efficacy of doxycycline combined with intramuscular (IM) interferon beta-1a (IFNb-1a) ...
Read more : Avonex plus Doxycycline trial preliminary results | Views : 4784 | Replies : 23 | Forum : Drug Pipeline


Interesting use of technology from the AAN Meeting

This abstract talks about using chip arrays to look at CSF. It seems that technology like this should enable a more thorough analysis of what's really going on at a protein-level...I think...



Identification of CSF Proteome Modifications in Multiple Sclerosis Using a Protein Chip Array Technology

Arnaud Lacour, Lille, Nord, France, Didier Lefranc, Jerome De Seze, Brigitte Onraed, Sylvain Dubucquoi, Gilbert Briand, Lionel Prin, Patrick Vermersch, Lille, France

OBJECTIVE: The aim of this study ...
Read more : Interesting use of technology from the AAN Meeting | Views : 935 | Replies : 0 | Forum : General Discussion






Stem cell treatment in Holland

Read more : Stem cell treatment in Holland | Views : 1390 | Replies : 0 | Forum : Stem Cells


Testosterone

Dear all,

I am off to Mauritius on Wednesday so will not be logging on again until after Easter (admit it you're all jealous).

The research is coming in thick and fast so I'll be interested to see what else has arrived when I return.

But here's one for my best friend Sharon - she's big on hormones and it looks like she's be barking up the right tree. As usual a small trial, but ...
Read more : Testosterone | Views : 1286 | Replies : 6 | Forum : General Discussion


Sixteen-Year Follow-up Study

First Avonex, then Rebif now Betaseron... next we need some "new" info on Copaxone.


Sixteen-Year Follow-up Study Reinforces Betaseron(R) Long-Term Efficacy, Safety and Tolerability in Multiple Sclerosis
Efficacy in relapse rate reduction beyond five years shown for the first time


Berlex announced today that Betaseron® (interferon beta 1b) remained consistently safe, effective and well tolerated over the long term, according to results of the Betaseron 16-Year Long-Term Follow-up (16-Year LTF) Study presented at the 58th ...
Read more : Sixteen-Year Follow-up Study | Views : 4520 | Replies : 4 | Forum : Betaseron


BHT-3009 Meeting/Info Results

There's some great info about the drug below.


Bayhill Therapeutics, Inc. Research on Multiple Sclerosis Chosen as One of the Meeting's Scientific Program Highlights at the 58th Annual Meeting of the American Academy of Neurology
4/4/2006 8:41:00 AM EST

Bayhill Therapeutics will make two presentations today at the 58th Annual Meeting of the American Academy of Neurology in San Diego in connection with development of the company's lead drug candidate, BHT-3009, for the treatment of ...
Read more : BHT-3009 Meeting/Info Results | Views : 1271 | Replies : 0 | Forum : Drug Pipeline


Better Rebif

A new and improved Rebif. Can't really see if it actually does anything better for the disease.

It's funny that as new therapies are on the horizon that Biogen published info yesterday that Avonex after first CIS substantially delayed dx of MS and now Serono has come up with a better Rebif.

The only interesting part of the article was "Serono also is taking a leading role in developing an understanding of the role of ...
Read more : Better Rebif | Views : 1416 | Replies : 1 | Forum : Drug Pipeline


Bladder

Not an MS stem cell story but big news today about the use of stem cells to create a bladder. It's good to know that lots of work is going on behind the scens which should, one day, hopefully be of use with this disease (to repair nerve fibres, or myelin. Or to grow another CNS).

Ian

http://news.bbc.co.uk/1/hi/health/4871540.stm
Read more : Bladder | Views : 1307 | Replies : 0 | Forum : Stem Cells


 

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