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Statin research...again

With all this statin research going on, I hope we get some clinical trial results some time this year.



Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: Relevance to multiple sclerosis.

Ann Neurol. 2006 May 25;
Ifergan I, Wosik K, Cayrol R, Kebir H, Auger C, Bernard M, Bouthillier A, Moumdjian R, Duquette P, Prat A.
Neuroimmunology Laboratory, Center for Research on Brain Diseases, Centre Hospitalier de l'Universite de Montreal (CHUM) Research Center, ...
Read more : Statin research...again | Views : 3373 | Replies : 2 | Forum : Statins


Potassium channels

Potassium channels keep popping up as an area to watch lately...



Potassium channels K(v)1.3 and K(v)1.5 are expressed on blood-derived dendritic cells in the central nervous system.

Ann Neurol. 2006 May 25;
Mullen KM, Rozycka M, Rus H, Hu L, Cudrici C, Zafranskaia E, Pennington MW, Johns DC, Judge SI, Calabresi PA.
Department of Neurology, Johns Hopkins University, Baltimore, MD.

OBJECTIVE: Potassium (K(+)) channels on immune cells have gained attention recently as promising targets of ...
Read more : Potassium channels | Views : 1223 | Replies : 2 | Forum : General Discussion


Axonal injury

The researchers have been busy this month. Another paper on what might cause axonal injury. Again, probably good news in that it might be another target for future treatment.

http://www.msif.org/en/research/researc ... xonal.html
Read more : Axonal injury | Views : 802 | Replies : 0 | Forum : General Discussion


Emerging therapeutic targets

Another paper suggesting that this complex disease is starting to be better understood.

http://www.msif.org/en/research/researc ... erape.html
Read more : Emerging therapeutic targets | Views : 819 | Replies : 0 | Forum : General Discussion


Neuro-protection

Looks like some progress is being made. The author is from the Institute of Neurology and highly regarded in this field.

http://www.msif.org/en/research/researc ... and_c.html
Read more : Neuro-protection | Views : 795 | Replies : 1 | Forum : General Discussion








Bladder dysfunction - any suggestions for improving?

Hi there,

I was just wondering if anyone has any suggestions for improving bladder dysfunction in MS? I've done a search in the forums but have only found passing references. I know it's not really something anyone likes to talk about, but it's certainly a problem for me, so I guess others are dealing with it too.

I am 34 and have been doing intermittent self-catherisation for about 18months and take 2.5mg of Ditropan twice ...
Read more : Bladder dysfunction - any suggestions for improving? | Views : 2586 | Replies : 13 | Forum : General Discussion


NAC reaction? Hope so...

Hi, since starting NAC I have lost senstation in one hand/arm. I had the same thing (with the other one!) when I had a serious "attack" in January, which has since gone back to normal.

I stared taking NAC in preparation for the ABX regime about 3 weeks ago (600Mg morning/night, 1200Mg after a week) and noticed this started a couple of days after.

I remember reading somewhere about bacterial die off causing these sort ...
Read more : NAC reaction? Hope so... | Views : 3731 | Replies : 5 | Forum : Antibiotics


 

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