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How long does Copaxone take to work?

My neuro, who originally diagnosed me PPMS (Dec 2005), now thinks I may be having an relapse... So, I've just done a round of coticosteroids and have be advised to consider a CRAB drug.

I suggested Copaxone, but the neuro felt that this drug takes too long to begin working. He mentioned that it can take 6 months too reach full effect. Has anyone heard of Copaxone taking this long to take effect?

By the ...
Read more : How long does Copaxone take to work? | Views : 9938 | Replies : 8 | Forum : Copaxone


I have been nauses for over a week now. Any suggestions till I get to my neuro Tuesday?
Read more : nausea | Views : 987 | Replies : 2 | Forum : General Discussion

Parasitic infection is found to benefit MS patients

I hope this was the right forum to place that hopeful news in.

I found it especially interesting when taking the following news in regard, where people in italy using BCG vaccination to generate immunetolerance - maybe its the same mechanism of action.


Parasitic infection is found to benefit MS patients

Patients with multiple sclerosis who also happen to have an intestinal parasite appear to have ...
Read more : Parasitic infection is found to benefit MS patients | Views : 5712 | Replies : 27 | Forum : General Discussion

Could I now be SPMS??

Hi everyone :) I have had MS for 13 years, so I am not new to the disease.

However, I am concerned that ever since my last relapse this past April, I have not been the same. Mosty it was my leg/foot was affected (had to get AFO) and that did come back.

However, I did develope daily tremors, spasms, pain, fatigue issues that remain to this ...
Read more : Could I now be SPMS?? | Views : 2992 | Replies : 14 | Forum : Daily Life

Cannabinor Phase 2a trial

Pharmos Announces Clinical Data from Phase 2a Trial of Cannabinor for Capsaicin-induced Pain

Safe and Well Tolerated with No Serious Adverse Effects

ISELIN, N.J., Jan. 19 /PRNewswire-FirstCall/ -. Pharmos Corp. today announced preliminary results from its Phase 2a study evaluating intravenous (i.v.) cannabinor, a CB2-selective synthetic cannabinoid compound, in a capsaicin-induced pain model. The drug candidate did not meet the primary endpoint defined by analgesic effects compared to placebo, but confirmed safety and tolerability observed ...
Read more : Cannabinor Phase 2a trial | Views : 800 | Replies : 0 | Forum : General Discussion

Imaging compounds

Bayer Schering To Develop Imaging Compounds To Detect Neurodegenerative Diseases

Bayer Schering Pharma AG has signed a license and option agreement with Taisho Pharmaceutical Co., Ltd., Nihon Nohyaku Co., Ltd., and the National Institute of Radiological Sciences, Japan, to develop novel imaging compounds for the detection of neurodegenerative diseases.
The diseases include Alzheimer's disease, Parkinson's disease and other disorders also associated with neuroinflammation such as multiple sclerosis.

Under the terms of the agreement Bayer Schering ...
Read more : Imaging compounds | Views : 1110 | Replies : 1 | Forum : General Discussion

Two papers on Vit D

1,25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis.

Muthian G, Raikwar HP, Rajasingh J, Bright JJ.
Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Experimental allergic encephalomyelitis (EAE) is a Th1 cell-mediated autoimmune disease model of multiple sclerosis (MS). Vitamin D deficiency is commonly observed in MS patients and vitamin D supplements reduce the clinical symptoms of EAE and MS. Earlier studies have shown that ...
Read more : Two papers on Vit D | Views : 2172 | Replies : 15 | Forum : General Discussion

MBP8298 starting phase III SPMS trial in US

The more the merrier...

BioMS gets FDA approval to start Phase 3 MS trial

Jan 19, 2007 - Reuters - BioMS Medical Corp. said on Friday it has received U.S. Food and Drug Administration approval to begin a Phase 3 trial of its multiple sclerosis treatment.

The two-year trial will involve about 500 patients in 50 centers across the United States, chief executive Kevin Giese told Reuters.

Giese said the trial of its treatment for ...
Read more : MBP8298 starting phase III SPMS trial in US | Views : 1481 | Replies : 2 | Forum : Drug Pipeline


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