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Puberty age and MS risk

This could go a long way to explaining why MS incidence is rising among women faster than men:

Age of puberty and the risk of multiple sclerosis: a population based study.

Eur J Neurol. 2008 Dec 23.
Ramagopalan SV, Valdar W, Criscuoli M, Deluca GC, Dyment DA, Orton SM, Yee IM, Ebers GC, Sadovnick AD; for the Canadian Collaborative Study Group*.
Wellcome Trust Centre for Human Genetics, and Department of Clinical Neurology, University of Oxford, ...
Read more : Puberty age and MS risk | Views : 1287 | Replies : 2 | Forum : General Discussion


Old leprosy drug effective against autoimmune diseases
Washington, Feb 1 (ANI): A century-old drug used to treat leprosy has shown promise in treating multiple sclerosis and other autoimmune diseases, say researchers.

The old drug called clofazimine, made in the 1890s originally failed to treat tuberculosis but has worked well as an antileprosy medicine.

"We never expected that an old antibiotic would hit this target that has been implicated in multiple sclerosis, psoriasis and type ...
Read more : Clofazimine | Views : 1697 | Replies : 0 | Forum : Drug Pipeline

Why autoimmune?

Hi all.

I have the feeling that I am missing something fundamental. Why is MS autoimmune? What is the evidence?

I disagree with this dogma, but I have been looking for studies in PubMed proving this hypothesis. But it is always considered as a fact without citation. What I have found so far is that SOMETIMES there are lymphocytes, either B or T, at the site of the lesion. How can this be enough?

Let ...
Read more : Why autoimmune? | Views : 3479 | Replies : 26 | Forum : General Discussion

Overlap of Multiple sclerosis and lyme disease

Interesting lecture about the overlap in multiple sclerosis and borrelia by Steven Phillips, M.D.:

also many other interesting presentations regarding this by other researchers and doctors:
Read more : Overlap of Multiple sclerosis and lyme disease | Views : 2510 | Replies : 0 | Forum : Antibiotics

Food Sensitivity

Gotta love my wife for finding this one...

Wow 8O
Read more : Food Sensitivity | Views : 1908 | Replies : 3 | Forum : General Discussion


I just wanted to ask if anyone has already tried homeopathy along with tysabri and if there were some reactions / results / feelings /whatever?
I'm on my 7th shot and I had quite a bad last month, difficulty walking and some urinary problems but it might be the winter season or something since it wasn't so bad before. however, my neuro says my last MRI which I did 1 month ago are excellent ...
Read more : homeopathy | Views : 2092 | Replies : 3 | Forum : Tysabri (Antegren or Natalizumab)


I am opening this thread to discuss possible connections between the material on the CCVI thread in the general discussion forum and CPn.

Rather than quote all the material for that 16 page forum thread, I'll assume readers have read the discussion over there, found here

1. Zamboni did blinded research on large numbers of patients in three studies that shows venous abnormalities in 100% of MS ...
Read more : CCVI / CPn | Views : 10474 | Replies : 33 | Forum : Antibiotics

Doxy plus interferon

Here's a BBC story on how doxycycline improved outcomes when, used alongside interferon in patients how had been poor responders to the interferon alone

Notice no body said word one about resistance .......... :wink:
The researchers believe that doxycycline, a member of the tetracycline family of antibiotics, may block an enzyme which destroys nerve cells, thus protecting the brain and ...
Read more : Doxy plus interferon | Views : 3301 | Replies : 11 | Forum : Antibiotics

MBP8298 no use for RRMS

Dirucotide (MBP8298) Phase II Study fails to meet primary endpoints in Multiple Sclerosis patients 30 January 2009

BioMS Medical Corp. announced that the MINDSET-01 study, an exploratory phase II clinical trial evaluating dirucotide in patients with relapsing-remitting multiple Sclerosis or MS failed to meet primary endpoints, annualized relapse rate or associated secondary MRI endpoints.

Further, the company said Dirucotide did meet mean change from baseline in the Expanded Disability Status Scale and the Multiple ...
Read more : MBP8298 no use for RRMS | Views : 1857 | Replies : 1 | Forum : Drug Pipeline

Promising stem cells trial results (in humans)

I posted this in the stem cell section, but thought it would be of general interest.

Read more : Promising stem cells trial results (in humans) | Views : 1652 | Replies : 2 | Forum : General Discussion


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