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Human Epigenome Project

Another international genetics effort brewing that has implications for MS research.

Forget mutations: geneticists are hunting for subtler changes to DNA.

December 16, 2005 - Nature - Geneticists are brewing plans for a collective effort, loosely patterned on the Human Genome Project, that would map subtle changes in DNA. Some say that these changes are just as important to our understanding of disease as straight mutations.

As many as half of the genetic alterations that ...
Read more : Human Epigenome Project | Views : 1055 | Replies : 1 | Forum : General Discussion

"Coming out" at work

We're running a poll over at Accelerated Cure Project about people's experiences of coming out or not about your MS in the work environment. The comments section has prompted some interesting stories. If you're interested in weighing in or just seeing the results, you can check it out here:
Read more : "Coming out" at work | Views : 817 | Replies : 0 | Forum : General Discussion

Please read this very carefully.

Please read this very carefully. (Copied from CPn Help)

I mentioned in my first blog at CPn Help
that there was much I didn't remember about the early days of my treatment. I have never been a terribly good record keeper, but I did start out keeping a journal. For a few days I even added to this daily, but soon I could go for a couple of weeks without adding anything. This period rapidly ...
Read more : Please read this very carefully. | Views : 1669 | Replies : 0 | Forum : Antibiotics

Stem cells for drug delivery?

A different way that stem cells could prove useful in neurodegenerative disorders.

Engineered stem cells show promise for sneaking drugs into the brain

December 15, 2005 - Eurekalert - One of the great challenges for treating Parkinson's diseases and other neurodegenerative disorders is getting medicine to the right place in the brain.

The brain is a complex organ with many different types of cells and structures, and it is fortified with a protective barrier erected ...
Read more : Stem cells for drug delivery? | Views : 1238 | Replies : 0 | Forum : Stem Cells

Hepatitis B vaccination and MS

Interesting hypothesis...

Multiple sclerosis and hepatitis B vaccination: Adding the credibility of molecular biology to an unusual level of clinical and epidemiological evidence.

Med Hypotheses. 2006;66(1):84-6. Epub 2005 Sep 19.
Comenge Y, Girard M.
23 rue du Commerce, 75015-Paris, France.

In spite of a huge number of reports of severe hazards after injection of hepatitis B vaccine (HBV), the issue is regularly raised that no mechanism is available for the development of central demyelinating disorders ...
Read more : Hepatitis B vaccination and MS | Views : 1325 | Replies : 5 | Forum : General Discussion

LDN and weightloss

Has anyone experienced weightloss while taking LDN? Normally one wouldn't mind losing a few pounds, I just don't want to miss an underlying problem. Thanks
Read more : LDN and weightloss | Views : 3885 | Replies : 3 | Forum : Low Dose Naltrexone


If there was a Father Christmas (Santa Claus to Americans) I would ask for some neuro-protection.

A report has been published about neuro-protection. I haven't got the report but the following article provides a summary of the key points. Hopefully, some of the drugs being examined will come good.

Read more : Neuro-protection | Views : 1312 | Replies : 8 | Forum : General Discussion

Skeptical but not a skeptic

Hello all,
This is my first post here, although I admit to lurking about for some time. The forum is outstanding and I have gained so much valuable information from everyone. Thank You!!

My husband was diagnosed in May, 2004--Since that time he has been on Avonex (Tysabri, briefly) and doing quite well. Well enough to finally have returned to his job as an airline pilot. He is also on a myriad of supplements-fish oil, ...
Read more : Skeptical but not a skeptic | Views : 3936 | Replies : 16 | Forum : Antibiotics

Stem cells to make mice better models?

Interesting article in light of the EAE discussion that goes on around here regularly -- make the mice a little more human and maybe their disease will be more like ours...

Trace of Human Stem Cells Put in Unborn Mice Brains

THE ASSOCIATED PRESS - December 13, 2005 - Scientists announced on Monday that they had created mice with small amounts of human brain cells in an effort to make realistic models of neurological disorders ...
Read more : Stem cells to make mice better models? | Views : 839 | Replies : 0 | Forum : General Discussion

a general MRI question

In what I will try to call "typical" MS, for which I know there is no typical... is it "typical" for MS MRI lesions to persist forever, or are they known to appear and disappear?

Read more : a general MRI question | Views : 1143 | Replies : 1 | Forum : General Discussion


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