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Ion Channel Knowledgebase

This isn't a breakthrough press release or anything, but I'm glad to read that an "Ion Channel Knowledgebase" exists because it seems there's something funny going on with our ion channels.

Aureus Pharma Licenses AurSCOPE Ion Channel Knowledgebase to Xention

June 29, 2006 -- PRNewswire -- Aureus Pharma a leading provider of knowledge management solutions to accelerate discovery in the life sciences industry, announces that Xention, a drug discovery and development company focusing on ion ...
Read more : Ion Channel Knowledgebase | Views : 960 | Replies : 1 | Forum : General Discussion


Dear all,

I would like to hear from others about how they cope with the losses and uncertainty related to this disease. I was dx two years ago with RR at 39. Completely out of the blue. Walking is now not great and my hobbies have all been lost (running, scuba diving, tennis). I like, all with this disease, have to deal with changing symptoms / daily embarassments etc etc.

In the two years, I ...
Read more : coping | Views : 4768 | Replies : 19 | Forum : Daily Life

ATL1102 Phase II trial starting

Antisense is finally restarting their phase II trial after getting caught in the tysabri whirlwind.

Commencement of dosing of patients in Phase IIa Multiple Sclerosis trial

June 21, 2006 - Press Release from Antisense Therapeutics - Antisense Therapeutics is pleased to report that dosing has commenced in the Phase IIa clinical trial of ATL1102 in patients with relapsing remitting multiple sclerosis (MS).

The study, a multi-centre, randomized, double-blinded, placebo-controlled clinical trial in approximately 80 patients ...
Read more : ATL1102 Phase II trial starting | Views : 2310 | Replies : 2 | Forum : Drug Pipeline

Tysabri in Europe

TYSABRI(R) Receives Approval in European Union for the Treatment of Relapsing Remitting Forms of Multiple Sclerosis

Biogen Idec and Elan Corporation, plc today announced that they received approval from the European Commission to market TYSABRI(R) (natalizumab) as a treatment for relapsing remitting multiple sclerosis (MS) to delay the progression of disability and reduce the frequency of relapses. TYSABRI is indicated as a single disease modifying therapy in highly active relapsing remitting MS for patients with ...
Read more : Tysabri in Europe | Views : 1342 | Replies : 0 | Forum : Tysabri (Antegren or Natalizumab)


Hi everybody, there´s a new forum here and I can share with you my "living problem". My boyfriend and me want to leave together (perhaps for all life : and we are in age to wonder about our together living.

But there´s my disease, you know. And I think I should take into account my perhaps disability in future. I know maybe it never come, but there´s a probability.

Does anybody solve similar problem as ...
Read more : living | Views : 1717 | Replies : 2 | Forum : Daily Life

Cannabinoids for PPMS trial

Cannabinoids for PPMS. I can't tell for sure if it's a large phase IIb, or a phase III study. I guess I'll say it's phase II unless somebody knows otherwise.

CUPID: Welcome to the CUPID study

What is CUPID?
CUPID stands for Cannabinoid Use in Progressive Inflammatory brain Disease. CUPID is a clinical trial which will evaluate whether THC, one of many chemical compounds (cannabinoids) found in the cannabis plant, might slow the development of ...
Read more : Cannabinoids for PPMS trial | Views : 1505 | Replies : 1 | Forum : Drug Pipeline

BBB Permeability?

Just wanted to gather all your knowledge on BBB Permeability reduction, and what we can do now. For example, with suppliments.

The thing that triggered this line of thought was probably the thread which had statins reducing BBB permeability.

Now I (think I) know tysabri works by making the stuff too big to pass through the BBB. And when I did a search on this site, i also came accross the article "Interferon-Beta Treatment ...
Read more : BBB Permeability? | Views : 3120 | Replies : 14 | Forum : General Discussion

Immunology research

Whether you are an auto-immune theory supporter or not, the immune system plays a key role in driving this disease. A new collaborative project has been announced -

New immunology research collaboration established

Singapore's Agency forScience, Technology and Research (A*STAR) and The Australian National University establish immunology research collaboration. A*STAR's Centre for Molecular Medicine (CMM) and the Australian Phenomics Facility based at The Australian National University (APF ANU) have established an immunology research partnership ...
Read more : Immunology research | Views : 897 | Replies : 1 | Forum : General Discussion

what to do

hey there everyone,
i just got done catching up with things on here...i finally went on a vacation...down to key west..had a great time....took care of myself while i was down there so as not to end up seeing someone down there...however i got back on saturday and on monday when i came into work i found out my neurologist had gone on vacation while i was gone and passed away...i mean dang now i ...
Read more : what to do | Views : 920 | Replies : 3 | Forum : General Discussion

Oral fumaric acid esters trial results

Here's the Pubmed entry for the recently completed BG12 study...I think...

Oral fumaric acid esters for the treatment of active multiple sclerosis: an open-label, baseline-controlled pilot study.

Eur J Neurol. 2006 Jun;13(6):604-10.
Schimrigk S, Brune N, Hellwig K, Lukas C, Bellenberg B, Rieks M, Hoffmann V, Pohlau D, Przuntek H.
Department of Neurology, St. Josef Hospital, Ruhr Universitat Bochum, Germany.

An exploratory, prospective, open-label study of fumaric acid esters (FAE, Fumaderm(R)) was conducted in patients ...
Read more : Oral fumaric acid esters trial results | Views : 4216 | Replies : 2 | Forum : Tecfidera (BG-12, dimethyl fumarate)


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