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Progression

We start a discussion on MS being possibly a collection of different diseases and then researchers publish an article suggesting that progression in the various sub-types has common features etc. It also suggests (from my understanding) that there is an underlying mechanism distinct from the immune sytem involvement / damage. As usual no insights into how this underlying mechanism could be halted.

It does pander to my real fear that even if you stopped the ...
Read more : Progression | Views : 6151 | Replies : 53 | Forum : General Discussion


Insurance/Medical Spending Account Question

Has anyone had experience with insurance or medical spending account claims for expenses indirectly related to MS (expenses other than medicines, doctor, hospital, MRI, etc.)? Health club dues for an MS patient, for example. If so, what types of expenses did you have covered and did you need to submit any additional documents, such as a letter of necessity from your doctor?

Thanks.
Read more : Insurance/Medical Spending Account Question | Views : 956 | Replies : 2 | Forum : General Discussion


LDN

Is there any one out there that has secondary progressive MS and finds help from LDN or does it mostly just help people with R&R form of MS.
Read more : LDN | Views : 2685 | Replies : 4 | Forum : Low Dose Naltrexone


FDA Makes Earliest Stages Of Clinical Trials More Efficient

An interesting FDA development that could speed the drug approval process in the US...



FDA Issues Advice to Make Earliest Stages Of Clinical Drug Development More Efficient

January 12, 2006 - The Food and Drug Administration (FDA) today announced steps to advance the earliest phases of clinical research in the development of innovative medical treatments. FDA’s goal is to improve the process for bringing safe and effective drugs for potentially serious and life-threatening diseases, such ...
Read more : FDA Makes Earliest Stages Of Clinical Trials More Efficient | Views : 1529 | Replies : 2 | Forum : Drug Pipeline


No real side effects

I have been on LDN for a few months now, probably around 6 months.

I am on the full 4.5mg/night dose.

I have never suffered from the side effects a lot of people talk about, and also, have not noticed the kick in energy levels either.

My filler is avicel, and its compounded by a reputable pharmacy (I got the name from someone else on this board).

In the begining, when my MS symptoms were ...
Read more : No real side effects | Views : 3110 | Replies : 5 | Forum : Low Dose Naltrexone


A few thoughts for Deb and others.

During recent months I haven't really been looking into the science behind MS. AS I continue to improve on my treatment I have spent less time musing on the whys and wherefores.

However, a conversation with Alasdair Coles and a chance conversation elsewhere got me thinking again. The upshot of the conversation with Alasdair was that MS is actually a group of diseases, not just one. The other conversation forced me to revisit my investigations ...
Read more : A few thoughts for Deb and others. | Views : 3246 | Replies : 15 | Forum : General Discussion


Hormone study

Here is study just released on the blockage of leptin, a hormone. "Shayk" since you are the "hormone" expert on the site, have you came across this particular hormone before?


Blocking Leptin Helps Halt And Heal Multiple Sclerosis
Category: Multiple Sclerosis News
Article Date: 13 Jan 2006 - 11am (UK)


Italian researchers have found that blockade of the hormone leptin, which is primarily produced in fats cells, has beneficial effects on the induction and progression ...
Read more : Hormone study | Views : 1352 | Replies : 3 | Forum : General Discussion


HSCT

Like many I want to halt this curse until some better treatments come along. I share the views of this guy who posted on the BCP site:


HSCT

This procedure is very efficious on early RRMS patients, when inflammation dominates. As the spectrum shifts from inflammatory in nature to progressive, it becomes less effective. It is not at all effective for primary progressive MS. Data suggest inflammation is held in check for at least 5-6 ...
Read more : HSCT | Views : 1301 | Replies : 0 | Forum : Drug Pipeline


I've forgotten I've got MS

MS has many symptoms which are seen in other conditions (tremors - Parkinsons, memory loss - Alzeimers). The following article suggests that demylination may be a feature of Alzeimers.

Ian


Breakdown of Myelin May Lead to Alzheimer's


WEDNESDAY, Jan. 4 (HealthDay News) -- A new study links the age-related breakdown of myelin, the fatty insulation coating brain cell connections, to the onset of Alzheimer's disease.

The report by researchers at the University of California, Los ...
Read more : I've forgotten I've got MS | Views : 1386 | Replies : 2 | Forum : General Discussion


Another cure

If there is a God I would really like to come back as a mouse with EAE in my next life. When the mouse goes to the mouse neurologist the latter can say 'you've got EAE, but don't worry we got 300 cures available (unlike those poor humans with their MS)'. This times it's Italian researchers and something called Leptin. We'll outside my knowledge base, but I wonder if statins have any role in regulating ...
Read more : Another cure | Views : 1612 | Replies : 7 | Forum : General Discussion


 

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