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Glenmark Pharma gets UK regulatory nod for GRC 4039

Glenmark Pharmaceuticals Ltd on February 21 announced that its candidate for Rheumatoid Arthritis, Inflammation and Multiple Sclerosis - GRC 4039, has entered Phase I trials.

This is with approval from the Medicines and Healthcare Products Regulatory Agency in the U.K. The company intends to develop GRC 4039 for Rheumatoid Arthritis.

Glenmark expects to complete Phase I trials for GRC 4039 by October 2008 and initiate Phase II by January 2009.

Source: The Hindu Business ...
Read more : Glenmark Pharma gets UK regulatory nod for GRC 4039 | Views : 1837 | Replies : 1 | Forum : Drug Pipeline

Pain question

I'm sure I'm being really dense but over the week I have started getting really sharp pain in my arm and leg that come for a couple of minutes then go away. It's happening a number of times throughout the day. Is this an MS thing or is my body just crap?
Read more : Pain question | Views : 4169 | Replies : 20 | Forum : General Discussion

Loobie's family - For real this time!


I joined photobucket and I think I have this figured out.


There's my ugly mug and my beautiful wife and daughter. Donations for plastic surgery are graciously accepted.
Read more : Loobie's family - For real this time! | Views : 2688 | Replies : 12 | Forum : General Discussion

DR15 allele

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I wonder how to test for the above genetic coding. I would guess I have this genetic code.
Read more : DR15 allele | Views : 1344 | Replies : 0 | Forum : General Discussion


I guess this is a vote of confidence for ATL1102 from Teva. The phase 2a trial is scheduled to report results around the middle of this year.

Antisense Therapeutics Ltd Licenses ATL1102 to Teva Pharmaceutical

February 20, 2008 - Antisense Therapeutics announced on February 11, 2008 that the Company had entered into an exclusive, world-wide license agreement with Teva to develop and commercialize ATL1102, a drug discovered by Isis Pharmaceuticals Inc. and licensed to ANP. ...
Read more : ATL1102 | Views : 2030 | Replies : 2 | Forum : Drug Pipeline

Another stem cell research article

Human Stem Cells Produce Healthy Neural Stem Cells In Rats 20 February 2008

Neural cells derived from human embryonic stem cells helped repair stroke-related damage in the brains of rats and led to improvements in their physical abilities after a stroke, in a new study by researchers at the Stanford University School of Medicine.

This study marks the first time researchers have used human embryonic stem cells to generate neural cells that grow well ...
Read more : Another stem cell research article | Views : 1993 | Replies : 1 | Forum : Stem Cells

FDA Proposed Off-Label Marketing Rule Changes

I wonder how/if this would impact MS off-label treatments. I would hope some of the chemotherapy drugs would receive more attention and traction as MS treatments.

FDA on Friday proposed new guidelines that would allow pharmaceutical and medical device companies to market their products for off-label uses, the New York Times reports (Harris, New York Times, 2/16). Currently, physicians can prescribe medications and medical devices for off-label uses, but companies cannot market their products for ...
Read more : FDA Proposed Off-Label Marketing Rule Changes | Views : 1379 | Replies : 0 | Forum : General Discussion


I know the are a few thoughts out there that strictly targeting T-cells is incomplete. I haven't kept up on the Rituxan trials but received an e-mail today from the Myelin Repair Foundation (that' probably not exactly right) and there seem to be some good results.....except for the death thing. So is it time to look forward to the Tovaxin/Rituxan cocktail? Thoughts on the Rituxan trial? Anyone?
Read more : Rituxan | Views : 2324 | Replies : 3 | Forum : Tcelna (Tovaxin)

3 years on ldn

This week marks three-years I have been taking LDN. I took 3mg for most of the time and within the last few months have upped it to 4.5mg. There was no real reason to go to 4.5, I just knew from reading that it was the 'optimal' dosage for females if you could manage it and when I had a few days off in a row I started at 4mg (only side effect was some ...
Read more : 3 years on ldn | Views : 5499 | Replies : 9 | Forum : Low Dose Naltrexone

Rebif & shortness of breath

Well, my longtime drug Copaxone stopped working for me last Spring, and I'm now taking Rebif. Trouble is, now I get short of breath very easily (even 1 flight of stairs.) I'm a very fit 41 year-old, I exercise regularly, and eat well. I've been to a pulmonary specialist and all tests came back normal.

Is there anyone out there who's had a similar experience with Rebif? I'm getting ready to ditch this one too, ...
Read more : Rebif & shortness of breath | Views : 1490 | Replies : 0 | Forum : General Discussion


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