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Biogen gets in on CDP323

Looks like Biogen is really trying to corner the market on new MS treatments.

UCB and Biogen Idec to Collaborate on Oral Multiple Sclerosis Therapy

MARKET WIRE -- October 02, 2006 -- UCB and Biogen Idec today announced a global collaboration to jointly develop and commercialize CDP323 for the treatment of relapsing-remitting multiple sclerosis (MS) and other potential indications. CDP323 is an orally active small molecule alpha4-integrin inhibitor expected to enter Phase II clinical trials ...
Read more : Biogen gets in on CDP323 | Views : 2718 | Replies : 1 | Forum : Drug Pipeline

Disability, axonal degeneration

I have been reading a little and understanding a little on this axonal degeneration and disability connection. Gary has lots of disability and little brain lesions, so it "fits" his MS. A few years ago they did a spinal MRI and a DR noted in a known area of attacks spinal atrophy. Which basically is shrinkage? I read in Lyon's article on another post about all of this except they were talking about the brain ...
Read more : Disability, axonal degeneration | Views : 3388 | Replies : 20 | Forum : General Discussion


This is a story of a couple of months ago, but is doing the rounds again. It's something cheery for a Monday.


MS treatment 'a miracle'

Rocky Point woman undergoes high-dose regimen at Stony Brook.
Linda Jacobellis had multiple sclerosis, a disease for which there is no cure, for 16 years. Now, she announces, "I no longer have MS." She ascribes her cure, in part, to "a miracle from my mother in heaven." ...
Read more : Cyclophosphamide | Views : 2000 | Replies : 6 | Forum : General Discussion

Genes story

This looks an interesing genes story
Read more : Genes story | Views : 1077 | Replies : 0 | Forum : General Discussion

Spiritual healing, medically verifiable. 170 lectures in U.S

Hi, my name is Neal and I want to share something very special with you. Please read below and before being critical, convince yourselves. Everyone has a duty to do this. What I am sharing you has helped me alot and has been a great gift in my life and thousands of others. But like I said, convince yourself. You can email me at if you have questions. Also, ...


hello all, new to this forum and copaxone and had a question.

was wondering if anyone else has had the same experience or could tell me what happened? :cry:

i have only been doing the shots for 2 weeks now and use the autoinject, and last week when i did my legs all was fine, but this week, the right leg when i gave ...
Read more : WRONG PLACE? | Views : 2331 | Replies : 4 | Forum : Copaxone

Betaferon and the BENEFIT study

Betaferon Demonstrates Robust Reduction in Risk of Developing Multiple Sclerosis Across All Subgroups of Benefit study

BERLIN, September 29, 2006-Schering AG (FSE: SCH, NYSE: SHR), Germany, announced today results from the subgroup analysis of the BENEFIT* study which showed that Betaferon® (interferon beta-1b) 250mcg treatment reduced the risk of developing clinically definite MS (CDMS) consistently across all subgroups regardless of age, gender, steroid treatment or symptoms at onset of disease.1 These data were part of ...
Read more : Betaferon and the BENEFIT study | Views : 887 | Replies : 0 | Forum : General Discussion

swollen lymph nodes

I have been on Rebif for about a month and a half now. I am getting swelling in the lymph nodes and around the front of the ear on the edge of the face. Slightly sore. Is this a common side effect with Rebif?
Read more : swollen lymph nodes | Views : 5209 | Replies : 5 | Forum : Rebif

Calpain inhibitor

I'm not very scientific but I did read that Calpain is a mediator of myelin breakdown so maybe this will be a promising avenue for research.

A novel calpain inhibitor for the treatment of acute experimental autoimmune encephalomyelitis.Hassen GW, Feliberti J, Kesner L, Stracher A, Mokhtarian F.
SUNY Downstate Medical Center, USA.

Aberrant activation of calpain plays a key role in the pathophysiology of several neurodegenerative disorders. Calpain is increasingly expressed in inflammatory cells in ...
Read more : Calpain inhibitor | Views : 1433 | Replies : 2 | Forum : Drug Pipeline

see general

I posted new research related to antibiotics in MS on the general forum here

I wanted people who were not using antibiotics already to see it as it has general interest, but for those already on board with antibiotics I wanted a thread here too. I'm sorry Aaron if I did this poorly, I did my best to do it in such a say everyones needs were met... ...
Read more : see general | Views : 1546 | Replies : 1 | Forum : Antibiotics


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