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Symadex Reverses EAE

Lucky mice... again.

Xanthus' Symadex Can Reverse Disease in Preclinical Multiple Sclerosis Animal Model
Thursday September 28, 9:30 am ET
- Results Presented at the 22nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis -

CAMBRIDGE, Mass., Sept. 28 /PRNewswire/ -- Xanthus Pharmaceuticals, Inc., a privately-held drug development company, today presented data that Symadex(TM) reverses the clinical and pathological signs of chronic disease in an animal model for multiple sclerosis (MS). ...
Read more : Symadex Reverses EAE | Views : 1504 | Replies : 2 | Forum : Drug Pipeline

FTY720 Phase II data

Phase II data looks impressive. Probably 3 years from coming to market (my guess).

The following also looks interesting, but there is no data on EDSS (yet).

In addition to its anti-inflammatory effects, preclinical data suggest that FTY720 may have the potential to reduce neurodegeneration and enhance repair of the central nervous system (CNS) affected by MS.

Read more : FTY720 Phase II data | Views : 1688 | Replies : 3 | Forum : Drug Pipeline

new rebif

Shame they couldn't have improved its efficacy! The bottom line is it still only reduces relapses by around 30%, but it's easier to take.


One-year Data From Phase III Trial Show That New Formulation of Rebif(r) Offers Substantial Improvement in Tolerability and Immunogenicity Profiles

Data Presented at 22nd ECTRIMS Congress in Madrid.

Serono announced today data from an ongoing two-year (96 weeks) Phase IIIb trial show that the new formulation of Rebif® (interferon beta-1a) ...
Read more : new rebif | Views : 1183 | Replies : 0 | Forum : Drug Pipeline

well i finally did it

well i finally did it there everyone..i finally snapped on my new neurologist this week..he sat there looked thru all my stuff and basically told me there was nothing he could do for me and that i just need to live witht he symptoms for to go back and see my regular family dr if anything changes.....i sat there and couldnt believe it.....he sat there and told me that since nothing was coming up ...
Read more : well i finally did it | Views : 2825 | Replies : 20 | Forum : General Discussion

Tysabri and Diabetes

Does anyone know if being a diabetic (either pill and diet modification or diet modification only) will hinder someone from getting Tysabri? I have a friend at a @#$%^&*()^% DR today and I know that DR will probably say you can't take it because of his blood sugar. He has been borderline diabetic for a couple of years and steroids has really pushed it over the edge.
Read more : Tysabri and Diabetes | Views : 2379 | Replies : 4 | Forum : Tysabri (Antegren or Natalizumab)

Bubonic plague

This should cheer everyone up who is following the Cpn theory. In this week's New Scientist (23 September 2006) there is an article, "If it stops plague, will it stop hospital superbugs?" which describes "relatives of the plague, such as chlamydia" sharing the same mechanisms which evade the innate immune system. Nice to know our disease may be related to the Black Death.

The article fortunately has researchers modifying the plague bacteria, Yersinia pestis, which ...
Read more : Bubonic plague | Views : 1694 | Replies : 1 | Forum : Antibiotics


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