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UK cannabis trial

The UK MS Society is seeking people with progressive MS to join a cannaboid trial.
Read more : UK cannabis trial | Views : 1072 | Replies : 0 | Forum : General Discussion

Conference in Baltimore

Dear all,

A link to Johns Hopkins PROJECT Restore. Also reference to a conference in Baltimore 19-23 July. Whilst it covers rare neurological problems, MS will also be covered.

Read more : Conference in Baltimore | Views : 998 | Replies : 0 | Forum : General Discussion


Parexel Drug Trial Had Shortfalls, U.K. Investigation Says

Parexel International Corp., which ran a clinical trial that left six men with multiple organ failure earlier this year, didn't have a doctor with adequate training and experience screening the patients, the U.K. health regulator said.

Parexel, based in Waltham, Massachusetts, failed to ensure that closely held German biotechnology company TeGenero AG, which developed the medicine, had proper insurance to cover the volunteers, the London-based Medicines ...
Read more : TGN1412 | Views : 1271 | Replies : 0 | Forum : Drug Pipeline

Canadians and Vit D

TORONTO (CP) - Sunlight may be the easiest and most natural way to get a health-enhancing dose of vitamin D, but Canadians should know that a little sun goes a long way, says a Canada-U.S. consensus group formed to determine the risks and benefits of exposure to ultraviolet rays.

In what has turned out to be a delicate balancing act, the group is advising that while too much time in the sun raises the risk ...
Read more : Canadians and Vit D | Views : 6142 | Replies : 42 | Forum : General Discussion



Trials not for MS, but something to keep in mind.


Synta launches human trials for anti-inflammatory drug

Synta Pharmaceuticals Corp. has launched two new midstage human clinical trials to test an anti-inflammatory drug.
The Lexington, Mass.-based private company said it had began dosing patients in two separate Phase II trials regarding the compound apilimod mesylate. One trial will focus on rheumatoid arthritis and the other will target common variable immunodeficiency, a condition ...
Read more : Synta | Views : 1234 | Replies : 0 | Forum : Drug Pipeline

MS Risk Influenced by Childhood Environment

Multiple Sclerosis Risk Influenced by Childhood Environment

TORONTO, ONTARIO--(CCNMatthews - May 24, 2006) -

Study of children and adults sheds new light on mysterious disease

The Multiple Sclerosis Society of Canada announced findings from a Canadian study that shows the risk of MS may be influenced by place of residence during childhood rather than ancestry. The study results were published in a recent edition of Neuroepidemiology.

The study puts into question the belief that MS ...
Read more : MS Risk Influenced by Childhood Environment | Views : 1879 | Replies : 3 | Forum : General Discussion

B cells

I'm glad to see some research from a reputable source on B cells and MS.

B lineage cells in the inflammatory central nervous system environment: Migration, maintenance, local antibody production, and therapeutic modulation.

Ann Neurol. 2006 May 22;59(6):880-892
Meinl E, Krumbholz M, Hohlfeld R.
Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, Martinsried, Munich, Germany.

B cells have long played an enigmatic role in the scenario of multiple sclerosis pathogenesis. This review summarizes recent progress in our ...
Read more : B cells | Views : 1369 | Replies : 1 | Forum : General Discussion

Here we go.....

This is to document my MS adventure....I hope someone finds it useful/interesting (apart from me!)

History: I was diagnosed in January 2006, at the time suffering some fairly severe difficulties walking, bladder disfunction and fatigue. I lost sensation on on side of my body and in one arm Looking back my first symptoms were in October 2004 when I had some hearing problems in one ear and difficulty passing water.

Currently: All my symptoms have ...
Read more : Here we go..... | Views : 2548 | Replies : 5 | Forum : Regimens



I think the following can be moved from Phase I to Phase II.


Cambrex to Produce Serum for Trial

Cambrex to Make Serum for Merrimack Pharmaceuticals Autoimmune Disease Study.

Cambrex Corp. said Tuesday one of its subsidiaries will produce a serum for a Merrimack Pharmaceuticals clinical study on autoimmune disease treatments.

The subsidiary, Cambrex Bio Science Hopkinton Inc., will produce trial quantities of Merrimack's lead drug candidate, MM-093, for the Phase II ...
Read more : Serum | Views : 1393 | Replies : 1 | Forum : Drug Pipeline


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