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NEjM article: Patients at risk for PML

N ENGL J MED 10.1056/NEJMe058123
new england journal
Patients at Risk
Jeffrey M. Drazen, M.D.
In clinical trials, the term “patients at risk” refers
to the altruistic people who volunteer to participate
in studies of novel treatments. In this issue of
three reports
provide details about
patients who were participating in trials involving
experimental treatment with natalizumab for either
multiple sclerosis or Crohn’s disease and who
were ...
Read more : NEjM article: Patients at risk for PML | Views : 1074 | Replies : 0 | Forum : General Discussion

Copaxone reduces relapase rates more than interferons

Since this is talking about all CRABs, I put it under "General Discussion"...

Copaxone(R) produced significantly greater reduction in relapse rate compared to beta interferon therapies

Robust treatment effects similar to pivotal trials demonstrate value of retrospective database comparison studies in mirroring clinical practice

June 9 -- CNW Telbec -- Results from a still on-going independent study published in the European Journal of Neurology demonstrate COPAXONE(R) (glatiramer acetate injection) is associated with lower relapse rates ...
Read more : Copaxone reduces relapase rates more than interferons | Views : 1700 | Replies : 5 | Forum : General Discussion

Hello new to this great information board!

My name is Kim I have had M.S for 14 years and still going.....I live in Arkansas moved from Michigan...No kids not married....One of my friends from another board I love suggested this one, very impressed lots of great info and support on here!
Another great place I love is
Hugs, Kimmie
Read more : Hello new to this great information board! | Views : 1594 | Replies : 2 | Forum : Introductions

Husband dx with Primary Progressive MS


My husband has recently been dx with PPMS. He started with a limp about 2 yrs ago. I only really noticed it becoming more frequent last July. I kept asking him about it and he said it was nothing. He is 46 y/o and I figured a big boy so I didn't do anything about it. Well, 2 months ago I asked him about again and why he wasn't exercising. He said when he ...
Read more : Husband dx with Primary Progressive MS | Views : 1809 | Replies : 6 | Forum : General Discussion

Positive results two Phase I/II clinical trials for Tovaxin

Positive interim results of two Phase I/II clinical trials for Tovaxin are released.

Hi, I am Tim,

Here is just a little of my story. So much has happened that I could write a book about my last two years. The vaccine appears to have arrested my disease and has done the same for the other people in the study.

I have two small websites that show a timeline of events. The first one ...
Read more : Positive results two Phase I/II clinical trials for Tovaxin | Views : 2139 | Replies : 2 | Forum : Drug Pipeline

FDA - New Drug Protocol

There's a good story on NPR's Morning Edition today about the FDA's procedure for follow up on newly approved drugs. There is a scientific review commitee (convening today) created to evaluate how this method can be improved.

Currently the FDA has 2 methods of follow up in place for fast track drugs:
1) Spontaneous Adverse Reaction Reporting System - almost totally ineffective because busy physicians, pharmacists, etc. do not take the initiative to report what ...
Read more : FDA - New Drug Protocol | Views : 1466 | Replies : 1 | Forum : Tysabri (Antegren or Natalizumab)


Anyone heard anything about this?
Read more : Tovaxin | Views : 1250 | Replies : 1 | Forum : General Discussion

Personal life ... if any ???

Hi everyone,
I start by saying how grateful I am to this site and its people. That's the main help that I'm getting from.
The question that's eating me away from inside though is how you go about your personal life ? Not all of us got the wretched diagnosis having a partner or being in a marriage. Don't even dare mean that it's any easier to deal with...
Sure it's a whole baggage of ...
Read more : Personal life ... if any ??? | Views : 1566 | Replies : 3 | Forum : General Discussion



I will be moving with my husband to Waynesville, North Carolina, in July :D Is anyone able to recommend a neurologist, family practitioner and an asthma doc in the area please. I'm happy with the ones I currently see but it is going to be too far to travel once we move.

Read more : SEEKING A NEUROLOGIST | Views : 1101 | Replies : 0 | Forum : General Discussion

Another conference

Dear all,

For information - another international ms conference is taking place at the end of the month in lovely Valencia, Spain (see link attached). Many of the participants presented at the UK MS Society research conference which was held at the end of May in beautiful Edinburgh, Scotland. Really looking forward to hearing the outcome of both and will post if I see anything. In my next life, I hope I come back as ...
Read more : Another conference | Views : 1252 | Replies : 1 | Forum : General Discussion


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