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Positive stem cells for a change

A story from my local newspaper. Professor Scolding is my neurologist and all round good egg. At my last appointment with him he intimated that he hopes to be starting human trials within a year.

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Hey Ian, if you start machine gunning MS researchers could you leave the Prof til last? I actually believe that he may be one of our best hopes for full restitution from MS ...
Read more : Positive stem cells for a change | Views : 1641 | Replies : 7 | Forum : General Discussion

Biogen deal for PML

from the Boston Globe

Alnylam, Biogen to partner on brain disease treatment
Alnylam Pharmaceuticals Inc. of Cambridge said it will collaborate with Biogen Idec Inc. to develop a treatment for a rare brain disease found in three patients taking Biogen Idec's multiple sclerosis drug Tysabri. Alnylam said Biogen Idec, also of Cambridge, would fund research to find a treatment for the disease, progressive multifocal encephalopathy. Alnylam will receive $5 million upfront and could earn up ...
Read more : Biogen deal for PML | Views : 5062 | Replies : 24 | Forum : Tysabri (Antegren or Natalizumab)

Prozac (fluoxetine) & neurogenesis ?

I followed an old article found here, that i raised a question on in the thread, and kept on hitting research that found that Prozac and related drugs caused new neurons to be made. I am guessing with prozacs proliferation, that some people here could have been on it at some time.

My question is, did you notice anything?

Although most if not all talk is on the hippocampus specifically.
Dr Anthony Hannan ...
Read more : Prozac (fluoxetine) & neurogenesis ? | Views : 3395 | Replies : 4 | Forum : Regimens

Desipramine & levetiracetam, anyone?

A few months back now, a member here (OddDuck) wrote an article regarding these two drugs. Has anyone tried either of these two drugs? in particular the Desipramine?

You can find the article i am speaking of at
Read more : Desipramine & levetiracetam, anyone? | Views : 2260 | Replies : 2 | Forum : Regimens

Oral Cladribine

Serono's Oral Cladribine for the Treatment of Multiple Sclerosis Awarded Fast Track Status by FDA

Serono announced today that oral cladribine has been designated a Fast Track product by the US Food and Drug Administration (FDA). This designation covers patients with relapsing forms of multiple sclerosis.
Serono's proprietary oral formulation of cladribine for the treatment of multiple sclerosis is currently being evaluated in a multi-center, multi-national Phase III study, CLARITY (CLAdRIbine Tablets Treating MS ...
Read more : Oral Cladribine | Views : 2114 | Replies : 9 | Forum : Drug Pipeline

Nicotiamide - B3 - may help MS...

Jeez, I hope this is true... Seems legit...
Read more : Nicotiamide - B3 - may help MS... | Views : 3731 | Replies : 21 | Forum : General Discussion

I need opinions!

Truthful, heartfelt, from your gut opinions.

Tovaxin trial: Would you/wouldn't you? why/why not?

I've been contacted. I qualify. They want me.

I'm not sure if I'm prepared to be a guinea pig...

I'm also not sure if I'm prepared to live with not giving it a try...

Thanks for your input. :)
Read more : I need opinions! | Views : 1580 | Replies : 3 | Forum : General Discussion

Double dosing

If a drug doesn't work that well - the solution is to double the dose! But this doesn't apply to Copaxone.
Read more : Double dosing | Views : 1483 | Replies : 4 | Forum : General Discussion

FTY720 Hype

Although I long for the day when I can pop a pill to treat my so called MS, what is the real benefit? I hate injections, so yes, this is a benefit, no more injections, but here are some things to think about:

1. MRI enhancing lesion reduction -- This doesn't correspond to disease activity, why do they insist on using this as a valid metric of effectiveness???

2. "The annualized relapse rate was reduced ...
Read more : FTY720 Hype | Views : 1527 | Replies : 6 | Forum : General Discussion

Exercise and MS

Apparently exercise is good for people with MS! Would have never guessed that. Lucky there were four researchers to conduct a study.
Read more : Exercise and MS | Views : 1536 | Replies : 4 | Forum : General Discussion


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