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Cerebral circulation time in MS is double that of normals

Full paper in pdf form.

Blinded study. Cerebral circulation and hypoxia in MS is not correlated with EDSS, disability, lesions or inflammation. It appears to precede all of this---

http://www.plosone.org/article/fetchObj ... tation=PDF

as Dr. Zamboni tweeted---now we need to understand how the venous system might be impacting this slowed cerebral blood flow in MS.


cheer


Cerebral circulation time in MS is double that of normals

New, blinded research shows cerebral circulation in pwMS takes twice as long as in normals, and this slowed blood flow does not correlate with EDSS or disability, or lesions and inflammation.

full paper in pdf form
http://www.plosone.org/article/fetchObj ... tation=PDF

The present study reported a significant CCT (cerebral circulation time) increase in MS patients compared to control subjects, indicating a consistent condition of cerebral hypoperfusion. Increase of CCT, and the ...
Read more : Cerebral circulation time in MS is double that of normals | Views : 312 | Replies : 3 | Forum : General Discussion


Opinions on NDC-1308?

This is exciting stuff I've read. Any opinions on this drug?
Read more : Opinions on NDC-1308? | Views : 182 | Replies : 0 | Forum : Drug Pipeline


Starting Tecfidera Soon

Hey everyone I'm a new MS diagnosed 23 year old choosing to have tecfidera ordered as my first medication. Do any of you have any advice for me? Is this a good option for my first medication? I appreciate the support.
Read more : Starting Tecfidera Soon | Views : 361 | Replies : 2 | Forum : Tecfidera (BG-12, dimethyl fumarate)




Walkaide for sale, $2000.

Along with a previous Bioness H20, I have acquired a Walkaide from a past family member.

It was purchased for around $5000.

It's in perfect condition with minimal usage according to the Walkaide clinician I talked to.

Model #: 20-1000.

Includes: Medium sized cuff, 10x packages of standard 1.25 electrodes (4 in each package) all accessories, ect, ect.

To have the device properly fitted you must visit a WalkAide retailer.

If interested email: ...
Read more : Walkaide for sale, $2000. | Views : 240 | Replies : 0 | Forum : Shopping


Low CD8+ T cell counts found with MS drug Tecfidera

A recent study found that patients taking dimethyl fumarate (Tecfidera) had low counts of CD8+ T cells, though their overall levels of lymphocytes were within the normal range. The findings suggest that doctors may want to monitor specific lymphocyte levels in addition to doing full blood cell counts.

In November 2014, Biogen Idec confirmed its first case of progressive multifocal leukoencephalopathy (PML), a rare brain infection, in a patient taking dimethyl fumarate (Tecfidera), and complications ...


Any thoughts...

Hi all,
Has anyone have any thoughts on the following...

I have been diagnosed 15 years, tried all sorts of things and consider myself to be fairly knowledgeable on many subjects related to MS. My most problematic symptom is gait/leg mobility, I can walk, slowly, for about 1/2 mile before things get too much of an effort and my legs stiffen so much that I need to stop - muscle fatigue plays a big part ...
Read more : Any thoughts... | Views : 232 | Replies : 1 | Forum : General Discussion




New treatment for MS fatigue suggested

The Multiple Sclerosis Journal has published the results of a study by researchers from Israel who measured the effect of vitamin D analogue, Alfacalcidol, on MS-related fatigue.<br><br>

Fatigue is one of the most common and disabling symptoms of multiple sclerosis, occurring in up to 90 per cent of people with MS.... Read more - http://www.ms-uk.org/mssymptomsresearch
Read more : New treatment for MS fatigue suggested | Views : 302 | Replies : 0 | Forum : General Discussion


 

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