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Changing natalizumab dosing frequency reduced risk for PML

Changing natalizumab dosing frequency reduced risk for Progressive Multifocal Leukoencephalopathy (PML)

A commonly-prescribed multiple sclerosis (MS) infusion medication linked to a rare but serious side effect is safer to use when dosing intervals are extended, according to a new study led by MS specialists at NYU Langone Health in New York…Read more -


Family Planning among Women with Relapsing MS

Survey Highlights Misconceptions about Family Planning among Women with Relapsing Forms of Multiple Sclerosis

Of 1,000 women diagnosed with relapsing remitting multiple sclerosis (RRMS) in the last five years, 88% were concerned they would not be able to have children, despite studies that show otherwise. This is according to a recent European survey conducted by Teva Pharmaceuticals Europe…Read more -

Read more : Family Planning among Women with Relapsing MS | Views : 404 | Replies : 0 | Forum : General Discussion

STEM Cells treatment for MS

Has anyone tried it? What was the outcome? Pl inform
Read more : STEM Cells treatment for MS | Views : 488 | Replies : 2 | Forum : General Discussion

EBV virus: Astrocytes and microglia (and B-cells) infected.

Epstein-Barr virus is present in the brain of most cases of multiple sclerosis and may engage more than just B cells.


Multiple sclerosis (MS) is a chronic neuroinflammatory condition of the central nervous system (CNS). It is a major cause of neurological disability in young adults, particularly women.

What triggers the destruction of myelin sheaths covering nerve fibres is unknown. Both genetic and infectious agents have been implicated. Of the infectious agents, Epstein-Barr virus ...

There is damage after the lesion

Maybe it is something that we knew, but now there is proof. After the MS lesion appears, the tissue damage continues.

Evidence of progressive tissue loss in the core of chronic MS lesions: A longitudinal DTI study.


Using diffusion tensor imaging (DTI), we examined chronic stable MS lesions, peri-lesional white matter (PLWM) and normal appearing white matter (NAWM) in patients with relapsing-remitting multiple sclerosis (RRMS) for ...
Read more : There is damage after the lesion | Views : 370 | Replies : 0 | Forum : MS Etiology and Pathogenesis

Color vision in multiple sclerosis

Do you remember the reports about improvement after PTA? Not sure about the relationship, but is worth to read about.

Impairment of acquired color vision in multiple sclerosis: an early diagnostic sign linked to the greatness of disease.

To assess the type and degree of both red-green and blue-yellow color vision deficiencies of Calabrian males affected by multiple sclerosis.

MATERIAL: Eighty Calabrian male patients were enrolled (age range ...

Biomarkers: MRZ reaction distinguish MS and other disorders

The MRZ reaction helps to distinguish rheumatologic disorders with central nervous involvement from multiple sclerosis.

Some rheumatologic disorders may initially manifest with central nervous system (CNS) affection, mimicking the clinical, magnetic resonance imaging, and cerebrospinal fluid findings of multiple sclerosis (MS). The MRZ reaction (MRZR), composed of the three respective antibody indices (AIs) against measles, rubella, and varicella zoster virus, has been found positive frequently in MS patients. ...

Long term effects

I was recently approved for this medication. I am also on the much younger spectrum in the population of MS.
Does any one have any long term experience with the medication?

For example:
Can I go into remission? Is this decided on MRIs?
How are organ functions long term?
Long term side effects if I come off the medication?
Read more : Long term effects | Views : 371 | Replies : 0 | Forum : Rituxan (Rituximab)

UNDIAGNOSED?? Be sure to look into dysautonomia/POTS

UNDIAGNOSED??? If you are still undiagnosed and you know something is really wrong, you need to make sure and look into dysautonomia/postural orthostatic tachycardia syndrome (POTS). This basically means that your autonomic nervous system is not functioning properly. Ask your neurologist or cardiologist about a “tilt table test”. The reason why I am saying this is because I spent 4 months trying to figure out what was wrong with me. I saw 10 different doctors ...
Read more : UNDIAGNOSED?? Be sure to look into dysautonomia/POTS | Views : 454 | Replies : 0 | Forum : General Discussion

Reregistered new/old member

Well I forgot my username and password. I had over 500 posts back in 2009-10
On Rebif for 5 years. Went off of it to try tecfidera. That didn’t work for me. Side effects were miserable. Been MS drug free for 4 years. No symptoms...
Last two weeks, my entire body feels like all muscles are locking up. Hard to walk, etc. Is this a normal progression? Every joint aches. Tested positive for ANA? GP ...
Read more : Reregistered new/old member | Views : 562 | Replies : 2 | Forum : General Discussion


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